Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Huaiyi Yang"'
Publikováno v:
Mycology, Vol 14, Iss 4, Pp 358-370 (2023)
ABSTRACTOur previous study revealed 11’-deoxyverticillin A (C42), a natural product isolated from the Ophiocordyceps-associated fungus Clonostachys rogersoniana and a member of the epipolythiodioxopiperazines (ETPs), induced both apoptosis and auto
Externí odkaz:
https://doaj.org/article/7fd9d4fefeae41d292714c4ef4d539e5
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)
Fatty acid alkyl esters have broad applications in biofuels, lubricant formulas, paints, coatings, and cosmetics. Traditionally, these esters are mostly produced through unsustainable and energy-intensive processes. In contrast, microbial production
Externí odkaz:
https://doaj.org/article/8e6e851d00f74a0eb7e195152d360156
Publikováno v:
Cellular and Molecular Biology. 68:68-73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66a82c2d37e5ab685ea41511ce2b24ba
https://doi.org/10.14715/cmb/2022.68.12.13
https://doi.org/10.14715/cmb/2022.68.12.13
The mechanism of the positive regulation of autophagy by mammalian target of rapamycin (mTOR) remains largely unknown. In the present study, we observed that inhibition of mTOR either genetically or pharmacologically suppressed basal and H2O2-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::160a931b05bd211dd874cec4755e2599
https://doi.org/10.21203/rs.3.rs-2866876/v1
https://doi.org/10.21203/rs.3.rs-2866876/v1
Autor:
Bin Huang, Tingwen Fan, Kaiyue Wang, Haicang Zhang, Chungong Yu, Shuyu Nie, Yangshuo Qi, Wei-Mou Zheng, Jian Han, Zheng Fan, Shiwei Sun, Sheng Ye, Huaiyi Yang, Dongbo Bu
Publikováno v:
Bioinformatics. 39
Motivation Computational protein sequence design has been widely applied in rational protein engineering and increasing the design accuracy and efficiency is highly desired. Results Here, we present ProDESIGN-LE, an accurate and efficient approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4011a096a996d7c81e85ec9fafd42944
https://doi.org/10.1093/bioinformatics/btad122
https://doi.org/10.1093/bioinformatics/btad122
Publikováno v:
Cell Biology International. 46:311-322
Akt is usually considered to be a negative regulator of both autophagy and adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) signaling. In the present study, we found that SC66, a pyridine-based allosteric Akt inhibitor, suppressed bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444948972b8062e5e7db69c4fec6301d
https://doi.org/10.1002/cbin.11732
https://doi.org/10.1002/cbin.11732
Autor:
Huaiyi Yang, Wang Yl, Zhijun Xi, Yanjie Wei, Gang Wang, Quan Gao, Yuqing Huo, Xuejun Jiang, Bolin Hou, Caining Zhang
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
Sunitinib (ST), a multitargeted receptor tyrosine kinase inhibitor, has been demonstrated to be effective for the treatment of renal carcinoma. It has been reported that ST is involved in the mediation of autophagy; however, its regulatory role in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18ba6c1184f60f6108c33efcf980bae
http://link.springer.com/article/10.1038/s41598-019-47597-4
http://link.springer.com/article/10.1038/s41598-019-47597-4
Nuclear-localized mitochondria were discovered over sixty years ago1; however, the function of these organelles in the initiation of nuclear formation and development remains unknown. Here, we showed that mitochondria fragmented into dense particles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d28f922750cb696c060982af8b2eb798
https://doi.org/10.1101/2020.11.06.372144
https://doi.org/10.1101/2020.11.06.372144
Publikováno v:
Chemistry & Biodiversity. 17
Chloropupukeananin (RN56-6) and Pestalofone C (RN56-49), isolated from the culture of the plant endophytic fungus Pestalotiopsis fici, have been shown cytotoxic, anti-HIV, and antimicrobial activities. However, the underlying mechanism of their regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d454dd41c63eefe70a75eebb61dd66d
https://doi.org/10.1002/cbdv.201900583
https://doi.org/10.1002/cbdv.201900583
Autor:
Guohua Yu, Liming Jiang, Yuanyuan Xu, Hongwei Guo, Huiyan Liu, Yi Zhang, Huaiyi Yang, Chonggang Yuan, Jiyan Ma
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48146 (2012)
Prion protein (PrP) is well studied for its pathogenic role in prion disease, but its potential contribution to other pathological processes is less understood. PrP is expressed in a variety of cancers and at least in pancreatic and breast cancers, i
Externí odkaz:
https://doaj.org/article/71d9b0a782d14669acb7fe38c93b7051