Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Huaixin Zheng"'
Autor:
Saima Rehman, Anna Katarina Antonovic, Ian E. McIntire, Huaixin Zheng, Leanne Cleaver, Maria Baczynska, Carlton O. Adams, Theo Portlock, Katherine Richardson, Rosie Shaw, Alain Oregioni, Giulia Mastroianni, Sara B-M. Whittaker, Geoff Kelly, Christian D. Lorenz, Arianna Fornili, Nicholas P. Cianciotto, James A. Garnett
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Bacterial adhesion is a fundamental process which enables colonisation of niche environments and is key for infection. However, in Legionella pneumophila, the causative agent of Legionnaires’ disease, these processes are not well understoo
Externí odkaz:
https://doaj.org/article/dc482835699a4915aefeb24d5457763d
Autor:
Yashu Wang, Qianru Li, Jiayu Zhang, Pingping Liu, Huaixin Zheng, Lijuan Chen, Zhen Wang, Chen Tan, Min Zhang, Hongxia Zhang, Wenqing Miao, Yuke Wang, Xiaoyan Xuan, Guoqiang Yi, Peng Wang
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTInflammatory bowel disease (IBD) represents a prominent chronic immune-mediated inflammatory disorder, yet its etiology remains poorly comprehended, encompassing intricate interactions between genetics, immunity, and the gut microbiome. This
Externí odkaz:
https://doaj.org/article/ed230e11a1ff40af830744e7ed63fa90
Autor:
Jie Qin, Xingchen Qiu, Guangming Gong, Yinan Guo, Lei Lei, Huaixin Zheng, Peng Wang, Xiaoyan Xuan
Publikováno v:
Intensive Care Research, Vol 3, Iss 1, Pp 30-37 (2022)
Abstract Background Acute spontaneous intracerebral hemorrhage (sICH) is a morbid and deadly form of stroke. The lymphocyte-to-monocyte ratio (LMR) and systemic immune-inflammation index (SII) are two novel markers of systemic inflammation. We aimed
Externí odkaz:
https://doaj.org/article/5bb71e27dabd46c7929ca2a643c5d059
Autor:
Marte I Flydal, Christa H Chatfield, Huaixin Zheng, Felizza F Gunderson, Oscar Aubi, Nicholas P Cianciotto, Aurora Martinez
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46209 (2012)
Legionella pneumophila is a pathogenic bacterium that can cause Legionnaires' disease and other non-pneumonic infections in humans. This bacterium produces a pyomelanin pigment, a potential virulence factor with ferric reductase activity. In this wor
Externí odkaz:
https://doaj.org/article/50fa7691edb441d3bf9c67a3d710f60b
Autor:
Pingping Liu, Peng Wang, Yashu Wang, Jiayu Zhang, Qianru Li, Ying Du, Xiaoyan Xuan, Huaixin Zheng
Publikováno v:
Bioscience Reports
Colorectal cancer (CRC) has been one of the most common malignancies worldwide, which tends to get worse for the growth and aging of the population and westernized lifestyle. However, there is no effective treatment due to the complexity of its etiol
Publikováno v:
Infection and Immunity. 87
It was previously determined that the type II secretion system (T2SS) promotes the ability of Legionella pneumophila to grow in coculture with amoebae. Here, we discerned the stage of intracellular infection that is potentiated by comparing the wild-
Autor:
Richard C, White, Hilary K, Truchan, Huaixin, Zheng, Jessica Y, Tyson, Nicholas P, Cianciotto
Publikováno v:
Infection and immunity. 87(11)
It was previously determined that the type II secretion system (T2SS) promotes the ability of Legionella pneumophila to grow in coculture with amoebae. Here, we discerned the stage of intracellular infection that is potentiated by comparing the wild-
Autor:
Joseph P. Vogel, Nicholas P. Cianciotto, Ki Woo Kim, Mohammed Kaplan, Huaixin Zheng, Grant J. Jensen, Debnath Ghosal
The type II secretion system (T2SS) is a multi-protein envelope-spanning assembly that translocates a wide range of virulence factors, enzymes and effectors through the outer membrane (OM) of many Gram-negative bacteria. Here, using electron cryotomo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aac4204029e1498b84ddf82d15c65a59
https://doi.org/10.1101/525063
https://doi.org/10.1101/525063
Autor:
Ian E. McIntire, Ki Woo Kim, Grant J. Jensen, Nicholas P. Cianciotto, Alberto E. Lopez, Hilary K. Truchan, Huaixin Zheng, Joseph P. Vogel, Mohammed Kaplan, Debnath Ghosal
Publikováno v:
Nature microbiology. 4(12)
The type II secretion system (T2SS) is a multiprotein envelope-spanning assembly that translocates a wide range of virulence factors, enzymes and effectors through the outer membrane of many Gram-negative bacteria1-3. Here, using electron cryotomogra
Iron Limitation Triggers Early Egress by the Intracellular Bacterial Pathogen Legionella pneumophila
Autor:
Soma Ghosh, Ralph R. Isberg, Tamara J. O’Connor, Susan M. VanRheenen, Huaixin Zheng, Nicholas P. Cianciotto
Publikováno v:
Infection and Immunity. 84:2185-2197
Legionella pneumophila is an intracellular bacterial pathogen that replicates in alveolar macrophages, causing a severe form of pneumonia. Intracellular growth of the bacterium depends on its ability to sequester iron from the host cell. In the L. pn