Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Huaiwei Ding"'
Autor:
Mingyue Liu, Chang Xu, Xiaochun Qin, Wenwu Liu, Deping Li, Hui Jia, Xudong Gao, Yuting Wu, Qiong Wu, Xiangbo Xu, Bo Xing, Xiaowen Jiang, Hongyuan Lu, Yingshi Zhang, Huaiwei Ding, Qingchun Zhao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Multidrug resistance (MDR) is considered as a primary hindrance for paclitaxel failure in non-small cell lung cancer (NSCLC) patients, in which P-glycoprotein (P-gp) is overexpressed and the PI3K/Akt signaling pathway is dysregulated. Previously, we
Externí odkaz:
https://doaj.org/article/73be0a8b86824748b5d564e77d5adb45
Autor:
Qiu Wang, Mengchi Sun, Chang Li, Dan Li, Zimeng Yang, Qikun Jiang, Zhonggui He, Huaiwei Ding, Jin Sun
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 2, Pp 203-212 (2021)
The therapeutic strategy that gives consideration to the combination of photodynamic therapy and chemotherapy, has emerged as a potential development of effective anti-cancer medicine. Nevertheless, co-delivery of photosensitizers (PSs) and chemother
Externí odkaz:
https://doaj.org/article/d891d5347da64088b945917ff8fc9f00
Autor:
Xiaochun Qin, Mingyue Liu, Chang Xu, Bo Xing, Xiangbo Xu, Yuting Wu, Huaiwei Ding, Qingchun Zhao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The PI3K/AKT pathway plays a central role in human cancers, aberrant activation of this pathway is associated with tumorigenesis, cancer progression and angiogenesis. Based on the importance of the PI3K/AKT pathway in malignancies, we developed a 4-a
Externí odkaz:
https://doaj.org/article/277cfddfa972461d9b442d5937f77803
Autor:
Xiaochun Qin, Mingyue Liu, Yuting Wu, Shu Wang, Siheng Lian, Hui Jia, Qiong Wu, Huaiwei Ding, Qingchun Zhao
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 9, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/21cb541f36864d17bed03e910e24f1a7
Publikováno v:
Catalysts, Vol 10, Iss 11, p 1339 (2020)
The construction of a C-S bond is a powerful strategy for the synthesis of sulfur containing compounds including sulfides, sulfoxides, and sulfones. Recent methodological developments have revealed lots of novel protocols for C-S bond formation, prov
Externí odkaz:
https://doaj.org/article/af206802051d4751ba0cff693df4d8dd
Autor:
Huaiwei Ding, Zhe Chen, Cunlong Zhang, Tian Xin, Yini Wang, Hongrui Song, Yuyang Jiang, Yuzong Chen, Yongnan Xu, Chunyan Tan
Publikováno v:
Molecules, Vol 17, Iss 4, Pp 4703-4716 (2012)
A series of novel compounds bearing imidazo[2,1-b]thiazole scaffolds were designed and synthesized based on the optimization of the virtual screening hit compound N-(6-morpholinopyridin-3-yl)-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide (5a), and
Externí odkaz:
https://doaj.org/article/4983bfc8003c4f48a193910e18585d16
Autor:
Chunyan Tan, Yuzong Chen, Yongnan Xu, Yuyang Jiang, Hongrui Song, Yini Wang, Cunlong Zhang, Tian Xin, Zhe Chen, Huaiwei Ding
Publikováno v:
Molecules, Vol 17, Iss 4, Pp 4703-4716 (2012)
A series of novel compounds bearing imidazo[2,1-b]thiazole scaffolds were designed and synthesized based on the optimization of the virtual screening hit compound N-(6-morpholinopyridin-3-yl)-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide (5a), and
Externí odkaz:
https://doaj.org/article/828f8cdbdce14c7db25ddabf1c06513a
Autor:
Huaiwei Ding, Kai Chen, Bingke Song, Chenglong Deng, Wei Li, Li Niu, Mengxuan Bai, Hongrui Song, Lijuan Zhang
Publikováno v:
Molecules, Vol 23, Iss 1, p 85 (2017)
Two series of benzamides compounds bearing piperidine groups were synthesized and the Gli-luc luciferase activity was screened by Gys-luc luciferase gene detection method. Compound 5q showed promising inhibition of hedgehog (Hh) signaling pathway. To
Externí odkaz:
https://doaj.org/article/2ee7894d254f42f588fd3a757bd11e93
Autor:
Chengze Zhu, Mingyue Liu, Yue Yuan, Huanhua Chen, Limeng Wu, Zizheng Cong, Qingchun Zhao, Huaiwei Ding
Publikováno v:
Bioorganicmedicinal chemistry letters. 72
Epigenetics regulate the gene expression and chromatin organization associated with the development and occurrence of cancer. Histone deacetylase inhibitors (HDACis) have been proved to be an effective epigenetic targeting drug for cancer treatment.
Autor:
Qingchun Zhao, Yaoguang Huang, Wenwu Liu, Shuoqi Huang, Deping Li, Huaiwei Ding, Xiaowen Jiang, Mingyue Liu, Xin Liu, Chengze Zhu, Limeng Wu, Huanhua Chen, Zihua Xu
Publikováno v:
SSRN Electronic Journal.