Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Huaijun Chen"'
Autor:
Chaoran Xu, Qia Zhang, Yi Zhang, Huaijun Chen, Tianchi Tang, Junjie Wang, Siqi Xia, Gao Chen, Jianmin Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Skull bone marrow is thought to be an immune tissue closely associated with the central nervous system (CNS). Recent studies have focused on the role of skull bone marrow in central nervous system disorders. In this study, we performed singl
Externí odkaz:
https://doaj.org/article/ff941c64f1fb4367b8fcd939d2d324b4
Autor:
Huaijun Chen, Chaoran Xu, Hanhai Zeng, Zhihua Zhang, Ning Wang, Yinghan Guo, Yonghe Zheng, Siqi Xia, Hang Zhou, Xiaobo Yu, Xiongjie Fu, Tianchi Tang, Xinyan Wu, Zihang Chen, Yucong Peng, Jing Cai, Jianru Li, Feng Yan, Chi Gu, Gao Chen, Jingyin Chen
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-17 (2023)
Abstract Background Subarachnoid hemorrhage (SAH) is an uncommon type of potentially fatal stroke. The pathophysiological mechanisms of brain injury remain unclear, which hinders the development of drugs for SAH. We aimed to investigate the pathophys
Externí odkaz:
https://doaj.org/article/4e90c1634dec43a8a8d3328197469c1d
Autor:
Junjie Cheng, Hanhai Zeng, Huaijun Chen, Linfeng Fan, Chaoran Xu, Huaping Huang, Tianchi Tang, Min Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Thrombocytopenia, characterized by a decrease in platelet count, is commonly observed in sepsis and COVID-19. In sepsis, thrombocytopenia can result from various mechanisms, including impaired platelet production in the bone marrow, accelerated plate
Externí odkaz:
https://doaj.org/article/36b5dffab3c141e1998a9562709b8d41
Autor:
Guangyu Ying, Wen Fang, Hanhai Zeng, Hongwen Ding, Huaijun Chen, Zhiqi Jiang, Lili Chen, Qiaoling Hu, Yongjian Zhu, Gao Chen
Publikováno v:
Materials & Design, Vol 227, Iss , Pp 111730- (2023)
Dural defects and subsequent leakage of cerebrospinal fluid (CSF) after neurosurgery are often associated with serious complications or even death. The associated surgical suture or sealant repair is often followed by pinhole leakage or a loose seal.
Externí odkaz:
https://doaj.org/article/cc98a301363644b38d6b7f845e14c074
Autor:
Hanhai Zeng, Huaijun Chen, Min Li, Jianfeng Zhuang, Yucong Peng, Hang Zhou, Chaoran Xu, Qian Yu, Xiongjie Fu, Shenglong Cao, Jing Cai, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Neuroinflammation and oxidative stress plays an important role in the pathogenesis of early brain injury (EBI) after subarachnoid hemorrhage (SAH). This study is the first to show that activation of autophagy protein nuclear recep
Externí odkaz:
https://doaj.org/article/d4653c589f4c45d483ca0e80f81a2ac4
Autor:
Yonghe Zheng, Linfeng Fan, Siqi Xia, Qiguo Yang, Zhihua Zhang, Huaijun Chen, Hanhai Zeng, Xiongjie Fu, Yucong Peng, Chaoran Xu, Kaibo Yu, Fuyi Liu, Shenglong Cao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
AimThe complement cascade is activated and may play an important pathophysiologic role in brain injury after experimental intracerebral hemorrhage (ICH). However, the exact mechanism of specific complement components has not been well studied. This s
Externí odkaz:
https://doaj.org/article/6897474fe4d94742b36631ad3305e98e
Autor:
Yinghan Guo, Jiang Liu, Hanhai Zeng, Lingxin Cai, Tingting Wang, Xinyan Wu, Kaibo Yu, Yonghe Zheng, Huaijun Chen, Yucong Peng, Xiaobo Yu, Feng Yan, Shenglong Cao, Gao Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe relationship between neutrophil to lymphocyte ratio (NLR) and poor outcome of aneurysmal subarachnoid hemorrhage (aSAH) is controversial. We aim to evaluate the relationship between NLR on admission and the poor outcome after aSAH.Metho
Externí odkaz:
https://doaj.org/article/6609dfd1bb5d45eaae73743f949c9b87
Autor:
Yucong Peng, Jianfeng Zhuang, Guangyu Ying, Hanhai Zeng, Hang Zhou, Yang Cao, Huaijun Chen, Chaoran Xu, Xiongjie Fu, Hangzhe Xu, Jianru Li, Shenglong Cao, Jingyin Chen, Chi Gu, Feng Yan, Gao Chen
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-20 (2020)
Abstract Background Neuroinflammation is closely associated with the poor prognosis in subarachnoid hemorrhage (SAH) patients. This study was aimed to determine the role of stimulator of IFN genes (STING), an essential regulator to innate immunity, i
Externí odkaz:
https://doaj.org/article/c0dc07953fd740abb1e2fad8df00e887
Autor:
Weiwei Sun, Jinglan Ma, Han Zhao, Chipeng Xiao, Hao Zhong, Hanzhi Ling, Zhen Xie, Qingqing Tian, Huaijun Chen, Tingting Zhang, Mu Chen, Shengwei Jin, Jianguang Wang
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-14 (2020)
Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and joint stiffness, finally leading to tissue destruction. Connective tissue growth factor (CTGF) is a critical factor in RA progression, whi
Externí odkaz:
https://doaj.org/article/988e786f52e34186bb1e87caac437152
Autor:
Hanhai Zeng, Kaibo Yu, Junyou Wang, Jingya Ye, Huaijun Chen, Chaoran Xu, Ting Chen, Feng Yan, Gao Chen, Chi Gu
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2586 (2023)
Hydrocephalus has been observed in rats with spontaneous hypertension (SHRs). It has been demonstrated that activation of the oxidative stress related protein retinoic acid receptor alpha (RARα) has neuroprotective impacts. Our investigation aims to
Externí odkaz:
https://doaj.org/article/6fa9faa2efc743f59d83bff6bd7714d8