Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Huaijin Zhou"'
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96203 (2014)
Macrophages and neutrophils generate a potent burst of reactive oxygen and nitrogen species as a key aspect of the antimicrobial response. While most successful pathogens, including the fungus Candida albicans, encode enzymes for the detoxification o
Externí odkaz:
https://doaj.org/article/ee33c24799444d598463e15b432650f3
Autor:
Slavena Vylkova, Aaron J. Carman, Heather A. Danhof, John R. Collette, Huaijin Zhou, Michael C. Lorenz
Publikováno v:
mBio, Vol 2, Iss 3 (2011)
ABSTRACT pH homeostasis is critical for all organisms; in the fungal pathogen Candida albicans, pH adaptation is critical for virulence in distinct host niches. We demonstrate that beyond adaptation, C. albicans actively neutralizes the environment f
Externí odkaz:
https://doaj.org/article/b5f598c3325045c9894e49f3763a387a
Publikováno v:
Journal of Bacteriology. 187:629-638
The MinD ATPase is critical to the oscillation of the Min proteins, which limits formation of the Z ring to midcell. In the presence of ATP, MinD binds to the membrane and recruits MinC, forming a complex that can destabilize the cytokinetic Z ring.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc22d816d64ac0ee4a775bb0ae1e227
https://doi.org/10.1128/jb.187.2.629-638.2005
https://doi.org/10.1128/jb.187.2.629-638.2005
Autor:
Joe Lutkenhaus, Huaijin Zhou
Publikováno v:
Journal of Bacteriology. 185:4326-4335
MinD binds to phospholipid vesicles in the presence of ATP and is released by MinE, which stimulates the MinD ATPase. Membrane binding requires a short conserved C-terminal region, which has the potential to form an amphipathic helix. This finding ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1acd920a0fe8b4baa54a327f7d5bda
https://doi.org/10.1128/jb.185.15.4326-4335.2003
https://doi.org/10.1128/jb.185.15.4326-4335.2003
Autor:
Michael C. Lorenz, Huaijin Zhou
Publikováno v:
Microbiology (Reading, England). 154(Pt 2)
Carbon starvation is a significant stress encountered by the opportunistic fungal pathogen Candida albicans, and mutations in several pathways required to assimilate non-fermentable carbon sources attenuate virulence. These pathways -- beta-oxidation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f0b219d1ec310506a19b741422a64e0
https://pubmed.ncbi.nlm.nih.gov/18227254
https://pubmed.ncbi.nlm.nih.gov/18227254
Autor:
Hadley Myers, Wiriya Chiranand, Michael C. Gustin, Michael C. Lorenz, Ian McLeod, Luis A. Vega, Huaijin Zhou, Jed J. Lynn, John R. Yates
Publikováno v:
Eukaryotic cell. 7(2)
This work has identified regulatory elements in the major fungal pathogen Candida albicans that enable response to nitrosative stress. Nitric oxide (NO) is generated by macrophages of the host immune system and commensal bacteria, and the ability to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06635a18dc18422035c139d73d346cc2
https://pubmed.ncbi.nlm.nih.gov/18083829
https://pubmed.ncbi.nlm.nih.gov/18083829
Autor:
Joe Lutkenhaus, Huaijin Zhou
The min locus encodes a negative regulatory system that limits formation of the cytokinetic Z ring to midcell by preventing its formation near the poles. Of the three Min proteins, MinC is the inhibitor and prevents Z-ring formation by interacting di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d970cbed64f5b1ebda57dbf2b8ed1e9
https://europepmc.org/articles/PMC1070367/
https://europepmc.org/articles/PMC1070367/
Autor:
Joe Lutkenhaus, Huaijin Zhou
Publikováno v:
Journal of bacteriology. 186(5)
MinD and MinC cooperate to form an efficient inhibitor of Z-ring formation that is spatially regulated by MinE. MinD activates MinC by recruiting it to the membrane and targeting it to a septal component. To better understand this activation, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf3df5d26ebee9f845b7d8d77680ebb
https://pubmed.ncbi.nlm.nih.gov/14973039
https://pubmed.ncbi.nlm.nih.gov/14973039
Autor:
Huaijin Zhou1,2, Lorenz, Michael C.1,2 Michael.Lorenz@uth.tmc.edu
Publikováno v:
Microbiology (13500872). Feb2008, Vol. 154 Issue 2, p500-509. 10p. 10 Black and White Photographs, 3 Diagrams, 2 Charts, 1 Graph.
Autor:
Huaijin Zhou1, Lutkenhaus, Joe1 jlutkenh@kumc.edu
Publikováno v:
Journal of Bacteriology. Apr2005, Vol. 187 Issue 8, p2846-2857. 12p. 3 Color Photographs, 44 Black and White Photographs, 1 Diagram, 2 Charts.