Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Huahua Wan"'
Autor:
Etsuro Nanishi, Marisa E. McGrath, Timothy R. O’Meara, Soumik Barman, Jingyou Yu, Huahua Wan, Carly A. Dillen, Manisha Menon, Hyuk-Soo Seo, Kijun Song, Andrew Z. Xu, Luke Sebastian, Byron Brook, Anna-Nicole Bosco, Francesco Borriello, Robert K. Ernst, Dan H. Barouch, Sirano Dhe-Paganon, Ofer Levy, Matthew B. Frieman, David J. Dowling
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-8 (2022)
A longitudinal study in mice reveals that a booster dose of mRNA vaccine BNT162b2 enhances humoral and cell-mediated responses and provides sterilizing immunity against Omicron-induced lung infection in aged animals.
Externí odkaz:
https://doaj.org/article/d52fa0bab2ac445194fcb3f7a844d6ba
Autor:
Shant H. Mahrokhian, Lisa H. Tostanoski, Catherine Jacob-Dolan, Roland C. Zahn, Frank Wegmann, Katherine McMahan, Jingyou Yu, Makda S. Gebre, Esther A. Bondzie, Huahua Wan, Olivia Powers, Tianyi Ye, Julia Barrett, Hanneke Schuitemaker, Dan H. Barouch
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Emerging SARS-CoV-2 variants with the potential to escape binding and neutralizing antibody responses pose a threat to vaccine efficacy. We recently reported expansion of broadly neutralizing activity of vaccine-elicited antibodies in humans
Externí odkaz:
https://doaj.org/article/e81f9a919d68445d8accd817d3d2a103
Autor:
Eric J. Nilles, Cecilia Then Paulino, Michael de St. Aubin, Angela Cadavid Restrepo, Helen Mayfield, Devan Dumas, Emilie Finch, Salome Garnier, Marie Caroline Etienne, Louisa Iselin, William Duke, Petr Jarolim, Timothy Oasan, Jingyou Yu, Huahua Wan, Farah Peña, Naomi Iihoshi, Gabriela Abdalla, Beatriz Lopez, Lucia de la Cruz, Bernarda Henríquez, Andres Espinosa-Bode, Yosanly Cornelio Puello, Kara Durski, Margaret Baldwin, Amado Alejandro Baez, Roland C. Merchant, Dan H. Barouch, Ronald Skewes-Ramm, Emily Zielinski Gutiérrez, Adam Kucharski, Colleen L. Lau
Publikováno v:
The Lancet Regional Health. Americas, Vol 16, Iss , Pp 100390- (2022)
Summary: Background: Population-level SARS-CoV-2 immunological protection is poorly understood but can guide vaccination and non-pharmaceutical intervention priorities. Our objective was to characterise cumulative infections and immunological protect
Externí odkaz:
https://doaj.org/article/1d7e657e248442058cf6a5f2683a817c
Autor:
Samuel J. Vidal, Elena Bekerman, Derek Hansen, Bing Lu, Kelly Wang, Judy Mwangi, William Rowe, Federico Campigotto, Jim Zheng, Darryl Kato, Abishek Chandrashekar, Julia Barrett, Shivani Patel, Huahua Wan, Tochi Anioke, Noe B. Mercado, Joseph P. Nkolola, Melissa J. Ferguson, William J. Rinaldi, Christian Callebaut, Wade Blair, Tomas Cihlar, Romas Geleziunas, Stephen R. Yant, Dan H. Barouch
Publikováno v:
Nature
Because no currently available vaccine can prevent HIV infection, pre-exposure prophylaxis (PrEP) with antiretrovirals (ARVs) is an important tool for combating the HIV pandemic1,2. Long-acting ARVs promise to build on the success of current PrEP str
Autor:
Joseph P. Nkolola, Jingyou Yu, Huahua Wan, Aiquan Chang, Katherine McMahan, Tochi Anioke, Catherine Jacob-Dolan, Olivia Powers, Tianyi Ye, Abishek Chandrashekar, Daniel Sellers, Julia Barrett, Yueh-Ming Loo, Mark T. Esser, Robert H. Carnahan, James E. Crowe, Dan H. Barouch
Publikováno v:
Science Translational Medicine. 14
Human monoclonal antibodies (mAbs) that target the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) offer a promising approach for the prevention and treatment of coronavirus disease 2019 (COVID-19). Given suboptimal
Autor:
Lisa H. Tostanoski, David R. Martinez, Laurent Pessaint, Deandre Bueno-Wilkerson, Felix Nampanya, Jinyan Liu, Abishek Chandrashekar, Daniel Valentin, Frank Wegmann, Katherine McMahan, Anthony L. Cook, Mark G. Lewis, Hanne Leth Andersen, Noe B. Mercado, Victoria M. Giffin, Ralph S. Baric, Renita Brown, Huahua Wan, Sarah Gardner, Caroline Atyeo, Roland Zahn, Galit Alter, Daniel Sellers, Amanda J. Martinot, Zack Flinchbaugh, Tochi Anioke, Shivani A. Patel, Aiquan Chang, Jingyou Yu, Tammy Hayes, Dan H. Barouch, Hanneke Schuitemaker, Owen Sanborn, David L. Hope, Joseph P. Nkolola, Catherine Jacob-Dolan, Esther A. Bondzie, Katherine Bauer, Elyse Teow
Publikováno v:
Nature
The emergence of SARS-CoV-2 variants that partially evade neutralizing antibodies poses a threat to the efficacy of current COVID-19 vaccines1,2. The Ad26.COV2.S vaccine expresses a stabilized spike protein from the WA1/2020 strain of SARS-CoV-2, and
Autor:
David Dowling, Etsuro Nanishi, Marisa McGrath, Timothy O'Meara, Soumik Barman, Jingyou Yu, Huahua Wan, Carly Dillen, Manisha Menon, Hyuk-Soo Seo, Kijun Song, Andrew Xu, Luke Sebastian, Byron Brook, Anna-Nicole Bosco, Francesco Borriello, Robert Ernst, Dan Barouch, Sirano Dhe-Paganon, Ofer Levy, Matthew Frieman
The SARS-CoV-2 Omicron variant evades vaccine-induced immunity. While a booster dose of ancestral mRNA vaccines effectively elicits neutralizing antibodies against variants, its efficacy against Omicron in older adults, who are at the greatest risk o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::798bc2d02fadfe0138011c28693463ce
https://doi.org/10.21203/rs.3.rs-1486748/v1
https://doi.org/10.21203/rs.3.rs-1486748/v1
Autor:
Xuan He, Malika Aid, Abishek Chandrashekar, Jingyou Yu, Katherine McMahan, Frank Wegmann, Catherine Jacob-Dolan, Jenny S. Maron, Caroline Atyeo, Huahua Wan, Daniel Sellers, Jinyan Liu, Michelle Lifton, Sarah Gardner, Esther A. Bondzie, Julia Barrett, Kunza Ahmad, Tochi Anioke, Jake Yalley-Ogunro, Jeanne Muench, Adrienne Goode, Hanne Andersen, Mark G. Lewis, Galit Alter, Hanneke Schuitemaker, Roland Zahn, Dan H. Barouch
Publikováno v:
Science Translational Medicine. 14
Ad26.COV2.S has demonstrated durability and clinical efficacy against symptomatic COVID-19 in humans. In this study, we report the correlates of durability of humoral and cellular immune responses in 20 rhesus macaques immunized with single-shot Ad26
Autor:
Jingyou Yu, Ai-ris Y. Collier, Marjorie Rowe, Fatima Mardas, John D. Ventura, Huahua Wan, Jessica Miller, Olivia Powers, Benjamin Chung, Mazuba Siamatu, Nicole P. Hachmann, Nehalee Surve, Felix Nampanya, Abishek Chandrashekar, Dan H. Barouch
Publikováno v:
medRxiv
The SARS-CoV-2 Omicron variant (B.1.1.529) has three major lineages BA.1, BA.2, and BA.31. BA.1 rapidly became dominant and has demonstrated substantial escape from neutralizing antibodies (NAbs) induced by vaccination2-4. BA.2 has recently increased
Autor:
Abishek Chandrashekar, Jingyou Yu, Katherine McMahan, Catherine Jacob-Dolan, Jinyan Liu, Xuan He, David Hope, Tochi Anioke, Julia Barrett, Benjamin Chung, Nicole P. Hachmann, Michelle Lifton, Jessica Miller, Olivia Powers, Michaela Sciacca, Daniel Sellers, Mazuba Siamatu, Nehalee Surve, Haley VanWyk, Huahua Wan, Cindy Wu, Laurent Pessaint, Daniel Valentin, Alex Van Ry, Jeanne Muench, Mona Boursiquot, Anthony Cook, Jason Velasco, Elyse Teow, Adrianus C.M. Boon, Mehul S. Suthar, Neharika Jain, Amanda J. Martinot, Mark G. Lewis, Hanne Andersen, Dan H. Barouch
Publikováno v:
bioRxiv
BackgroundThe rapid spread of the SARS-CoV-2 Omicron (B.1.1.529) variant, including in highly vaccinated populations, has raised important questions about the efficacy of current vaccines. Immune correlates of vaccine protection against Omicron are n