Zobrazeno 1 - 10
of 352
pro vyhledávání: '"Huahao Shen"'
Autor:
Chen Zhu, Qingyu Weng, Shenwei Gao, Fei Li, Zhouyang Li, Yinfang Wu, Yanping Wu, Miao Li, Yun Zhao, Yinling Han, Weina Lu, Zhongnan Qin, Fangyi Yu, Jiafei Lou, Songmin Ying, Huahao Shen, Zhihua Chen, Wen Li
Publikováno v:
Cell Death and Disease, Vol 15, Iss 8, Pp 1-10 (2024)
Abstract Eosinophils, traditionally associated with allergic phenomena, play a pivotal role in inflammatory responses. Despite accumulating evidence suggesting their pro-inflammatory function upon activation, the underlying mechanisms governing eosin
Externí odkaz:
https://doaj.org/article/0d83f4a82daa466f887f27690bc4d5e3
Autor:
Min Zhang, Lixia Xia, Wenbei Peng, Guogang Xie, Fei Li, Chao Zhang, Madiha Zahra Syeda, Yue Hu, Fen Lan, Fugui Yan, Zhangchu Jin, Xufei Du, Yinling Han, Baihui Lv, Yuejue Wang, Miao Li, Xia Fei, Yun Zhao, Kaijun Chen, Yan Chen, Wen Li, Zhihua Chen, Qiong Zhou, Songmin Ying, Huahao Shen
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract Malignant pleural effusion (MPE) is a common occurrence in advanced cancer and is often linked with a poor prognosis. Eosinophils were reported to involve in the development of MPE. However, the role of eosinophils in MPE remains unclear. To
Externí odkaz:
https://doaj.org/article/a0026bea35e34a13bd62f03864bcb03c
Autor:
Shiyi Yang, Kaijun Chen, Jinkang Yu, Zhangchu Jin, Min Zhang, Zhouyang Li, Yang Yu, Nanxia Xuan, Baoping Tian, Na Li, Zhengtong Mao, Wenbing Wang, Tianpeng Chen, Yinfang Wu, Yun Zhao, Xia Fei, Songmin Ying, Wen Li, Fugui Yan, Xingxian Zhang, Gensheng Zhang, Huahao Shen, Zhihua Chen
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111024- (2024)
Summary: Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a severe inflammatory condition that remains refractory; however, its molecular mechanisms are largely unknown. Previous studies have shown numerous compounds containing 4
Externí odkaz:
https://doaj.org/article/52c0939c0cb640ce8900b60d6e12ccc6
Autor:
Zhangchu Jin, Zhehua Shao, Shiyi Yang, Anyi Guo, Yinling Han, Yinfang Wu, Yun Zhao, Yanping Wu, Jiaxin Shen, Min Zhang, Xueqin Zhan, Wenqi Diao, Songmin Ying, Chao Zhang, Wen Li, Huahao Shen, Zhihua Chen, Fugui Yan
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-12 (2023)
Abstract Increased levels of cytosolic DNA in lung tissues play an important role in acute lung injury. However, the detailed mechanisms involved remain elusive. Here, we found that cyclic GMP-AMP synthase (cGAS, a cytosolic DNA sensor) expression wa
Externí odkaz:
https://doaj.org/article/9d8fdb23e2c54d8892c764508dbbb9a1
Autor:
Jieping Lei, Ke Huang, Sinan Wu, Jianying Xu, Yongjian Xu, Jianping Zhao, Xiangyan Zhang, Chunxue Bai, Yuanlin Song, Jian Kang, Pixin Ran, Yumin Zhou, Huahao Shen, Fuqiandg Wen, Kewu Huang, Yahong Chen, Wanzhen Yao, Tieying Sun, Yingxiang Lin, Jianguo Zhu, Guangliang Shan, Ting Yang, Chen Wang
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 45, Iss , Pp 101021- (2024)
Summary: Background: The prevalence, epidemiological and clinical heterogeneities, and impact profiles of individuals with preserved ratio impaired spirometry (PRISm), pre-COPD, young COPD, and mild COPD in general Chinese population were not known y
Externí odkaz:
https://doaj.org/article/915971297a7f412f85eeb49b24e17715
Autor:
Jinxuan Li, Jianying Xu, Lan Yang, Yongjian Xu, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Kewu Huang, Wanzhen Yao, Tieying Sun, Guangliang Shan, Ting Yang, Yingxiang Lin, Jianguo Zhu, Ruiying Wang, Zhihong Shi, Jianping Zhao, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Gang Hou, Yumin Zhou, Wen Li, Liren Ding, Hao Wang, Yahong Chen, Yanfei Guo, Fei Xiao, Yong Lu, Xiaoxia Peng, Biao Zhang, Zuomin Wang, Hong Zhang, Xiaoning Bu, Xiaolei Zhang, Li An, Shu Zhang, Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Lirong Liang, Bin Cao, Huaping Dai, Kian Fan Chung, Zhengming Chen, Jiang He, Sinan Wu, Dan Xiao, Chen Wang
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, p e53170 (2024)
BackgroundMaternal smoking during pregnancy (MSDP) is a known risk factor for offspring developing chronic obstructive pulmonary disease (COPD), but the underlying mechanism remains unclear. ObjectiveThis study aimed to explore whether the increased
Externí odkaz:
https://doaj.org/article/d9594d6c71da4b9da4fce65adf9b1d74
Autor:
Haide Chen, Xiunan Fang, Jikai Shao, Qi Zhang, Liwei Xu, Jiaye Chen, Yuqing Mei, Mengmeng Jiang, Yuting Wang, Zhouyang Li, Zihang Chen, Yang Chen, Chengxuan Yu, Lifeng Ma, Peijing Zhang, Tianyu Zhang, Yuan Liao, Yuexiao Lv, Xueyi Wang, Lei Yang, Yuting Fu, Daobao Chen, Liming Jiang, Feng Yan, Wei Lu, Gao Chen, Huahao Shen, Jingjing Wang, Changchun Wang, Tingbo Liang, Xiaoping Han, Yongcheng Wang, Guoji Guo
Publikováno v:
Advanced Science, Vol 11, Iss 5, Pp n/a-n/a (2024)
Abstract Tumor heterogeneity and its drivers impair tumor progression and cancer therapy. Single‐cell RNA sequencing is used to investigate the heterogeneity of tumor ecosystems. However, most methods of scRNA‐seq amplify the termini of polyadeny
Externí odkaz:
https://doaj.org/article/01953b985e0544b0bfd027fd4e59e028
Autor:
Dingyi Wang, Guohui Fan, Sinan Wu, Ting Yang, Jianying Xu, Lan Yang, Jianping Zhao, Xiangyan Zhang, Chunxue Bai, Jian Kang, Pixin Ran, Huahao Shen, Fuqiang Wen, Kewu Huang, Yahong Chen, Tieying Sun, Guangliang Shan, Yingxiang Lin, Guodong Xu, Ruiying Wang, Zhihong Shi, Yongjian Xu, Xianwei Ye, Yuanlin Song, Qiuyue Wang, Yumin Zhou, Wen Li, Liren Ding, Chun Wan, Wanzhen Yao, Yanfei Guo, Fei Xiao, Yong Lu, Xiaoxia Peng, Biao Zhang, Dan Xiao, Zuomin Wang, Xiaoning Bu, Hong Zhang, Xiaolei Zhang, Li An, Shu Zhang, Jianguo Zhu, Zhixin Cao, Qingyuan Zhan, Yuanhua Yang, Lirong Liang, Huaping Dai, Bin Cao, Jiang He, Chen Wang, for the China Pulmonary Health (CPH) Study Group
Publikováno v:
COPD, Vol 19, Iss 1, Pp 118-124 (2022)
Objective We aimed to establish an easy-to-use screening questionnaire with risk factors and suspected symptoms of COPD for primary health care settings. Methods Based on a nationwide epidemiological study of pulmonary health among adults in mainland
Externí odkaz:
https://doaj.org/article/3e212c5158fe4d829f9c9dc79b91c44a
Autor:
Jianmeng Zhou, Fang Yi, Feng Wu, Pusheng Xu, Meihua Chen, Huahao Shen, Lin Lin, Yunhui Zhang, Suyun Li, Changgui Wu, Yadong Yuan, Gang Wang, Xianwei Ye, Ping Zhang, Huaping Tang, Qianli Ma, Lanqing Huang, Zhongmin Qiu, Haiyan Deng, Chen Qiu, Guochao Shi, Jiayu Pan, Wei Luo, Kian Fan Chung, Nanshan Zhong, Kefang Lai, the CPA Cohort Study Group
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Asthma is a heterogeneous disease with variable symptoms, which presents with cough either as the sole or predominant symptom with or without wheezing. We compared the clinical and pathophysiological characteristics of cough predo
Externí odkaz:
https://doaj.org/article/157856e373694389b853033176ff2885
Autor:
Xia Fei, Jiaqi Huang, Fei Li, Yuejue Wang, Zhehua Shao, Lingling Dong, Yinfang Wu, Boran Li, Xue Zhang, Baihui Lv, Yun Zhao, Qingyu Weng, Kaijun Chen, Min Zhang, Shiyi Yang, Chao Zhang, Wen Li, Songmin Ying, Qiming Sun, Zhihua Chen, Huahao Shen
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112586- (2023)
Summary: The nuclear factor κB (NF-κB) pathway plays essential roles in innate and adaptive immunity, but little is known how NF-κB signaling is compartmentalized and spatiotemporally activated in the cytoplasm. Here, we show that the lipogenesis
Externí odkaz:
https://doaj.org/article/775d7d7ab197426da8526461943f4206