Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Huabao, Xiong"'
Autor:
Aijun Yang, Xiaoli Kong, Qin Wang, Runqing Miao, Haixiang Ma, Anzhuo Chu, Zhengtong Wang, Jiaqing Lu, Bo Liu, Bingcheng Mu, Runhan Guo, Jiayi Li, Xiaoxiao Gongye, Huabao Xiong, Tao Zhong
Publikováno v:
Genes and Diseases, Vol 12, Iss 1, Pp 101290- (2025)
Externí odkaz:
https://doaj.org/article/bad9da4488504d069f584848f03386ab
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Fatty acid metabolism, particularly fatty acid synthesis, is a very important cellular physiological process in which nutrients are used for energy storage and biofilm synthesis. As a key enzyme in the fatty acid metabolism, fatty acid synth
Externí odkaz:
https://doaj.org/article/a0fad61222e546b0b497c2844dbd5919
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-8 (2023)
Abstract Psoriasis is one of the most common inflammatory diseases, characterized by scaly erythematous plaques on the skin. The accumulated evidence on immunopathology of psoriasis suggests that inflammatory reaction is primarily mediated by T helpe
Externí odkaz:
https://doaj.org/article/ac0ab64d5393455896a0a1fedadd1382
Autor:
Changying Wang, Hongyan Cheng, Fenglian Yan, Hui Zhang, Junfeng Zhang, Chunxia Li, Mingsheng Zhao, Dongmei Shi, Huabao Xiong
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTUrinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) can lead to severe kidney injury. However, the molecular mechanisms underlying the pathological process of kidney injury are still incompletely understood. In the
Externí odkaz:
https://doaj.org/article/4960f7cbd2734af5bbaf899e4c749c4f
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Macrophages are highly heterogeneous and plastic, and have two main polarized phenotypes that are determined by their microenvironment, namely pro- and anti-inflammatory macrophages. Activation of pro-inflammatory macrophages is closely associated wi
Externí odkaz:
https://doaj.org/article/886b6e370d05489393ce3fa48ddb0562
Autor:
Lauren A. Peters, Joshua R. Friedman, Aleksandar Stojmirovic, Jacob Hagen, Sander Houten, Tetyana Dodatko, Mariana P. Amaro, Paula Restrepo, Zhi Chai, J. Rodrigo Mora, Holly A. Raymond, Mark Curran, Radu Dobrin, Anuk Das, Huabao Xiong, Eric E. Schadt, Carmen Argmann, Bojan Losic
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Longitudinal changes in gene expression, splicing patterns and adaptive immune repertoire in murine models of colitis are examined and associated with histologic inflammation in mice and in patients with inflammatory bowel disease.
Externí odkaz:
https://doaj.org/article/95a2a99b4f784d3c91deb9675e5c43a3
Autor:
Rou Zhao, Baoyu He, Qingli Bie, Jinghe Cao, Haoran Lu, Zhixin Zhang, Jing Liang, Li Wei, Huabao Xiong, Bin Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Cancer stem cells (CSCs) are regarded as the "seed cells" for tumorigenesis, metastasis, recurrence and drug resistance. However, specific surface markers of CSCs of different origins have not been documented. Methods Single-cell
Externí odkaz:
https://doaj.org/article/06d233450a3d4706b9e87c289fb0891c
Autor:
Junfeng Zhang, Yunsheng Zhang, Zhiya Yang, Dalei Cheng, Hui Zhang, Li Wei, Chen Liu, Fenglian Yan, Chunxia Li, Guanjun Dong, Changying Wang, Dongmei Shi, Huabao Xiong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Although psoriasis is classified as a T cell-mediated inflammatory disease, the contribution of myeloid cells to the pathogenesis of psoriasis is not fully understood. In the present study, we demonstrated that the expression of the anti-inflammatory
Externí odkaz:
https://doaj.org/article/eab6689b9b844dc89d5c7f4824e1a7b3
Autor:
Di Wang, Yunkai Lin, Feihong Xu, Hui Zhang, Xiaoyan Zhu, Zhen Liu, Yuan Hu, Guanjun Dong, Bingqi Sun, Yanhong Yu, Guoren Ma, Zhigang Tang, Diana Legarda, Adrian Ting, Yuan Liu, Jia Hou, Liwei Dong, Huabao Xiong
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104278- (2022)
Summary: Background: To determine whether SIRPα can be a diagnostic marker of pulmonary tuberculosis (PTB) and the molecular mechanism of SIRPα regulating macrophages to kill Mycobacterium tuberculosis (MTB). Methods: Meta-analysis combined with su
Externí odkaz:
https://doaj.org/article/80e092b23e7b4a6d9b1eddd3a4cd08cf
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Immunoglobulin E (IgE) elevation is a hallmark of allergic conditions such as atopic dermatitis (AD). The pathogenesis of AD is typically associated with high levels of IL-4 and IL-13 produced by activated T helper 2 (Th2) cells. Psoriasis, on the ot
Externí odkaz:
https://doaj.org/article/b76a7a5a41974b05adc6a4da5d72aeae