Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Hua-an Tseng"'
Autor:
Sanaya N. Shroff, Eric Lowet, Sudiksha Sridhar, Howard J. Gritton, Mohammed Abumuaileq, Hua-An Tseng, Cyrus Cheung, Samuel L. Zhou, Krishnakanth Kondabolu, Xue Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Rhythmic neural network activity has been broadly linked to behavior. However, it is unclear how membrane potentials of individual neurons track behavioral rhythms, even though many neurons exhibit pace-making properties in isolated brain ci
Externí odkaz:
https://doaj.org/article/ccfc97b3d7934471b978e4eb372e7ff0
Autor:
Rebecca A. Mount, Mohamed Athif, Margaret O’Connor, Amith Saligrama, Hua-an Tseng, Sudiksha Sridhar, Chengqian Zhou, Emma Bortz, Erynne San Antonio, Mark A. Kramer, Heng-Ye Man, Xue Han
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Mutations in autism spectrum disorder (ASD) risk genes disrupt neural network dynamics that ultimately lead to abnormal behavior. To understand how ASD-risk genes influence neural circuit computation during behavior, we analyzed the hippocampal netwo
Externí odkaz:
https://doaj.org/article/65d61882ea574b178f3ca2025495a3f0
Autor:
Eric Lowet, Daniel J. Sheehan, Ulises Chialva, Rodrigo De Oliveira Pena, Rebecca A. Mount, Sheng Xiao, Samuel L. Zhou, Hua-an Tseng, Howard Gritton, Sanaya Shroff, Krishnakanth Kondabolu, Cyrus Cheung, Yangyang Wang, Kiryl D. Piatkevich, Edward S. Boyden, Jerome Mertz, Michael E. Hasselmo, Horacio G. Rotstein, Xue Han
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112906- (2023)
Summary: Hippocampal CA1 neurons generate single spikes and stereotyped bursts of spikes. However, it is unclear how individual neurons dynamically switch between these output modes and whether these two spiking outputs relay distinct information. We
Externí odkaz:
https://doaj.org/article/b5652001c01443b4ab56188e0408577e
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 297- (2023)
Externí odkaz:
https://doaj.org/article/87b49b64665f4c4bac3058ff27b85bda
Autor:
Ying Jiang, Hyeon Jeong Lee, Lu Lan, Hua-an Tseng, Chen Yang, Heng-Ye Man, Xue Han, Ji-Xin Cheng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Low-intensity ultrasound can be used for neuromodulation in vivo, but it has poor spatial confinement and can result in unwanted cochlear pathway activation. Here the authors use the optoacoustic effect to generate spatially confined ultrasound waves
Externí odkaz:
https://doaj.org/article/dd56232a95df4f95bdb7bdd299d54472
Autor:
Sheng Xiao, Eric Lowet, Howard J. Gritton, Pierre Fabris, Yangyang Wang, Jack Sherman, Rebecca A. Mount, Hua-an Tseng, Heng-Ye Man, Christoph Straub, Kiryl D. Piatkevich, Edward S. Boyden, Jerome Mertz, Xue Han
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103263- (2021)
Summary: Recent improvements in genetically encoded voltage indicators enabled optical imaging of action potentials and subthreshold transmembrane voltage in vivo. To perform high-speed voltage imaging of many neurons simultaneously over a large anat
Externí odkaz:
https://doaj.org/article/f4c5cb22516847659db00337a7b75365
Autor:
Hua-an Tseng, Jack Sherman, Emma Bortz, Ali Mohammed, Howard J. Gritton, Seth Bensussen, Rockwell P. Tang, Dana Zemel, Thomas Szabo, Xue Han
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102955- (2021)
Summary: Ultrasound modulates brain activity. However, it remains unclear how ultrasound affects individual neurons in the brain, where neural circuit architecture is intact and different brain regions exhibit distinct tissue properties. Using a high
Externí odkaz:
https://doaj.org/article/dc312c54269f4294b3e38edd4e8a91fb
Autor:
Hua-an Tseng, Xue Han
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Prefrontal cortex (PFC) are broadly linked to various aspects of behavior. During sensory discrimination, PFC neurons can encode a range of task related information, including the identity of sensory stimuli and related behavioral outcome. However, i
Externí odkaz:
https://doaj.org/article/808a9c26a13c4cdf9aa4cd99745a9c11
Autor:
Sanaya N. Shroff, Shoshana L. Das, Hua-an Tseng, Jad Noueihed, Fernando Fernandez, John A. White, Christopher S. Chen, Xue Han
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: Precise measurement of action potentials (APs) is needed to observe electrical activity and cellular communication within cardiac tissue. Voltage-sensitive dyes (VSDs) are traditionally used to measure cardiac APs; however, they require acut
Externí odkaz:
https://doaj.org/article/80eb3f956de6450181eedcf9ffb18acc
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 294-303 (2018)
Summary: More specific and broadly applicable viral gene-targeting tools for labeling neuron subtypes are needed to advance neuroscience research, especially in rodent transgenic disease models and genetically intractable species. Here, we develop a
Externí odkaz:
https://doaj.org/article/1aceda2a21504bdeb83a737c8993930e