Výsledky vyhledávání - "Hua-Zhou Ying"

Discovery of Novel Succinate Dehydrogenase Inhibitors by the Integration of in Silico Library Design and Pharmacophore Mapping

Autor: Hua-Zhou Ying, Ting-Ting Yao, Shao-Wei Fang, Jin-Hao Zhao, Li Zhongshan, Jing-Li Cheng, Douxin Xiao, Xiao-Wu Dong, Yongjun Du

Publikováno v: Journal of agricultural and food chemistry. 65(15)

Succinate dehydrogenase (SDH) has been demonstrated as a promising target for fungicide discovery. Crystal structure data have indicated that the carboxyl “core” of current SDH inhibitors contributed largely to their binding affinity. Thus, ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d68329474b5b326ac1acb8e0ad76a87
https://pubmed.ncbi.nlm.nih.gov/28358187

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(±)-(3aRS,4SR)-9-Chloro-2-(2-chloro-4-nitrophenyl)-4-(4-chlorophenyl)-3a,4-diethoxy-6,8-dimethoxychromano[4,3-d]-Δ1,9b-1,2,3-thiadiazoline

Autor: Hua-Zhou Ying, Yong-Zhou Hu

Publikováno v: Acta Crystallographica Section E Structure Reports Online. 61:o416-o418

The title compound, C27H24Cl3N3O7S, contains a thiadiazoline ring which is almost planar. The two ethoxy groups bonded at the 3a- and 4-positions are in a trans configuration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4719e9b59d06ef8b24502f25e0714164
https://doi.org/10.1107/s1600536805001807

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Akademický článek

(±)-(3a RS,4 SR)-9-Chloro-3a,4-diethoxy-6,8-dimethoxy-2-(2-chloro-4-nitrophenyl)-4-(4-chlorophenyl)chromano[4,3- d]-Δ^1,9^b-1,2,3-thiadiazoline.

Autor: Yong-Zhou Hu¹ huyz@zjuem.zju.edu.cn, Hua-Zhou Ying¹

Publikováno v: Acta Crystallographica: Section E. Feb2005, Vol. 61 Issue 2, po416-o418. 3p. 3 Diagrams, 2 Charts.

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