Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Hua-Ying Fan"'
Autor:
Ming-Yan Yang, Ze-Yu Song, Hai-Lin Gan, Mei-Hua Zheng, Qian Liu, Xiang-Ting Meng, Tao Pan, Zhen-Yuan Li, Ruo-Xuan Peng, Ke Liu, Hua-Ying Fan
Publikováno v:
BMC Pharmacology and Toxicology, Vol 23, Iss 1, Pp 1-11 (2022)
Abstract Background Toxicological problem associated with herbal medicine is a significant public health problem. Hence, it is necessary to elaborate on the safety of herbal medicine. Salvianolic acid A (SAA) is a major active compound isolated from
Externí odkaz:
https://doaj.org/article/de5355d8a3ec4921b2345811f5009807
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13991- (2023)
Objective: To perform a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate acupuncture's clinical effect on insulin resistance (IR) in women with polycystic ovary syndrome (PCOS). Methods: PubMed, Cochrane Library,
Externí odkaz:
https://doaj.org/article/4d150717f49e4dd28b146c5efa2046ad
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 361 (2022)
Oxidative stress contributes to numerous diseases, including cancer. CSB is an ATP-dependent chromatin remodeler critical for oxidative stress relief. PARP1 is the major sensor for DNA breaks and fundamental for efficient single-strand break repair.
Externí odkaz:
https://doaj.org/article/ac970be1fe67407a9cbba0e58aad435c
Autor:
Robert J Lake, Erica L Boetefuer, Pei-Fang Tsai, Jieun Jeong, Inchan Choi, Kyoung-Jae Won, Hua-Ying Fan
Publikováno v:
PLoS Genetics, Vol 10, Iss 4, p e1004284 (2014)
Cockayne syndrome is an inherited premature aging disease associated with numerous developmental and neurological defects, and mutations in the gene encoding the CSB protein account for the majority of Cockayne syndrome cases. Accumulating evidence s
Externí odkaz:
https://doaj.org/article/8028cbe89872461cbdfdf92577e401f7
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004204 (2014)
Mechanisms that maintain transcriptional memory through cell division are important to maintain cell identity, and sequence-specific transcription factors that remain associated with mitotic chromatin are emerging as key players in transcriptional me
Externí odkaz:
https://doaj.org/article/1b344b75b1a9471dbfe5fa29f1b2199b
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e110124 (2014)
Danshensu, a type of dihydroxyphenyl lactic acid, is one of the most abundant active phenolic acids in the dried root of Salvia miltiorrhizae (Lamiaceae)--widely used traditional Chinese medicine. The effects of danshensu on platelet aggregation and
Externí odkaz:
https://doaj.org/article/bcc93bed50c34805b22ed0d30cf181a0
Publikováno v:
PLoS Genetics, Vol 9, Iss 4, p e1003407 (2013)
The Cockayne syndrome complementation group B (CSB) protein is essential for transcription-coupled DNA repair, and mutations in CSB are associated with Cockayne syndrome--a devastating disease with complex clinical features, including the appearance
Externí odkaz:
https://doaj.org/article/1f991fce1d0949a1b2766e056b69ec3a
Autor:
Deborah F Kelly, Robert J Lake, Teije C Middelkoop, Hua-Ying Fan, Spyros Artavanis-Tsakonas, Thomas Walz
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10532 (2010)
The Notch receptor links cell fate decisions of one cell to that of the immediate cellular neighbor. In humans, malfunction of Notch signaling results in diseases and congenital disorders. Structural information is essential for gaining insight into
Externí odkaz:
https://doaj.org/article/6628aab852a842ee8e23212563010ba8
Autor:
Marc Lavigne, Ragnhild Eskeland, Saliha Azebi, Violaine Saint-André, Suk Min Jang, Eric Batsché, Hua-Ying Fan, Robert E Kingston, Axel Imhof, Christian Muchardt
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000769 (2009)
The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. These proteins contain two related domains known as the chromo- and the chromoshadow-domain. The chromo-domain binds histone H3 tails methylated on lysine
Externí odkaz:
https://doaj.org/article/7b7d538d14c34f8483cc97b765d7c9dd
Publikováno v:
PLoS Genetics, Vol 4, Iss 3, p e1000031 (2008)
Cockayne syndrome (CS) is a devastating progeria most often caused by mutations in the CSB gene encoding a SWI/SNF family chromatin remodeling protein. Although all CSB mutations that cause CS are recessive, the complete absence of CSB protein does n
Externí odkaz:
https://doaj.org/article/35a6c90c3e694185b36ddc02b7bcf841