Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hua-Tai Xu"'
Publikováno v:
eLife, Vol 12 (2024)
In the process of synaptic formation, neurons must not only adhere to specific principles when selecting synaptic partners but also possess mechanisms to avoid undesirable connections. Yet, the strategies employed to prevent unwarranted associations
Externí odkaz:
https://doaj.org/article/336a92e6804e4ba999325b179e293725
Autor:
Zhuolei Jiao, Taosha Gao, Xiaofei Wang, Wen Zhang, Nasim Biglari, Emma E Boxer, Lukas Steuernagel, Xiaojing Ding, Zixian Yu, Mingjuan Li, Mingkun Hao, Hua Zhou, Xuanzi Cao, Shuaishuai Li, Tao Jiang, Jiamei Qi, Xueyan Jia, Zhao Feng, Biyu Ren, Yu Chen, Xiaoxue Shi, Dan Wang, Xinran Wang, Luyao Han, Yikai Liang, Congcong Wang, E Li, Yue Hu, Zi Tao, Humingzhu Li, Yu Xiang, Min Xu, Hung-Chun Chang, Yifeng Zhang, Hua-tai Xu, Jun Yan, Anan Li, Qingming Luo, Ron Stoop, Scott Sternson, Jens C. Bruning, Mu-ming Poo, David J Anderson, Hui Gong, Yangang Sun, Xiao-Hong Xu
The hypothalamus plays a vital role in coordinating essential neuroendocrine, autonomic, and somatomotor responses for survival and reproduction. While previous studies have explored population-level projections of hypothalamic neurons, the specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34b3b166afcd00b1ee7c6a49be980f7b
https://doi.org/10.1101/2023.05.25.542241
https://doi.org/10.1101/2023.05.25.542241
Publikováno v:
SSRN Electronic Journal.
During the process of synaptic formation, neurons require not only certain principles for selecting partners to form synapses but also additional mechanisms to avoid undesired cells. However, the means to get around unwanted partners remains largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46ee901b4c7d2bd41a3e2e47b4ce826d
https://doi.org/10.1101/2021.11.03.467093
https://doi.org/10.1101/2021.11.03.467093
Publikováno v:
Current Biology. 32:3137-3145.e3
Dissecting neural connectivity patterns within local brain regions is an essential step to understanding the function of the brain.
Autor:
Yu Wei, Junming Zhang, Linyu Shi, Xinde Hu, Xiaowen Shen, Ni Gao, Cheng Tang, Junlai Liu, Hui Yang, Haibo Zhou, Wenqin Ying, Fei Liu, Changyang Zhou, Pengyu Huang, Xu Zhang, Zhiping Rao, Xuan Yao, Hua-Tai Xu, Yidi Sun, Changlin Li, He Li, Leping Cheng
Publikováno v:
Nature Neuroscience. 21:440-446
Despite rapid progresses in the genome-editing field, in vivo simultaneous overexpression of multiple genes remains challenging. We generated a transgenic mouse using an improved dCas9 system that enables simultaneous and precise in vivo transcriptio
Autor:
Hua-Tai Xu, Mingzhe Liu, Zhaorong Chen, Yifeng Zhang, Haishan Yao, Yingsi Zhou, B. D. Wang, Jinlin Su, Yidi Sun, Linyu Shi, He Li, Qingquan Xiao, Cheng Tang, Haibo Zhou, Fei Liu, Sanlan Li, Wenyan Wu, Xinde Hu, Canbin Feng, Linhan Wang, Hui Yang, Changyang Zhou
Publikováno v:
Cell. 181(3)
Summary Conversion of glial cells into functional neurons represents a potential therapeutic approach for replenishing neuronal loss associated with neurodegenerative diseases and brain injury. Previous attempts in this area using expression of trans
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
U0126 (1,4-diamino-2,3-dicyano-1,4-bis (2-aminophenylthio) butadiene), a widely used mitogen-activated protein kinase kinase (MEK) inhibitor, was found to accelerate voltage-gated K+ channel (KV) inactivation in heterologous cells expressing several
Publikováno v:
Nature Neuroscience. 10:549-551
Determining the degree of synapse formation and elimination is essential for understanding the structural basis of brain plasticity and pathology. We show that in vivo imaging of dendritic spine dynamics through an open-skull glass window, but not a