Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hua-Hao Chiu"'
Autor:
Hua-Hao Chiu, Jen-Shin Song, Wan-Ping Hsieh, Ming-Shiu Hung, Cheng-Ming Chu, Kak-Shan Shia, Yen-Shih Tung, Chun-Ping Chang, Yu-Sheng Chao, Shi-Liang Tseng, Chien-Huang Wu, Yinchiu Lin, Wan-Ling Chung, Chia-Liang Tai, Chun-Wei Kuo
Publikováno v:
Journal of Medicinal Chemistry. 51:5397-5412
Replacing the conventional pyrazole 5-aryl substituent of 1 (SR141716A) with the 2-thienyl moiety appended with an appropriate alkynyl unit, a novel class of 5-(5-alkynyl-2-thienyl)pyrazole derivatives, behaving as highly potent CB1 receptor antagoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b64e510b20574a19246cd45c653dbca
https://doi.org/10.1021/jm800066v
https://doi.org/10.1021/jm800066v
Autor:
Chao Yu-Sheng, Min-Tsang Hsieh, Chia Chien Hsieh, Kak Shan Shia, Chun Wei Kuo, Hui Chuan Wu, Wan Ping Hsieh, Chia Liang Tai, Ming Shiu Hung, Jing Po Tsao, Jen Shin Song, Shi Liang Tseng, Vijay D. Pawar, Hua Hao Chiu
Publikováno v:
Org. Biomol. Chem.. 6:447-450
A novel class of (5-(pent-1-enyl)thiophen-2-yl)pyrazole antagonists was discovered, many of which exhibited potent CB1 activity and good CB1/2 selectivity, suggesting that along with a 1,3-transposition of the carbonyl of the pyrazole 3-carboxamide,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9987dad5bd20a2eca00a967c3c825a42
https://doi.org/10.1039/b716434c
https://doi.org/10.1039/b716434c
Autor:
Shi-Liang, Tseng, Ming-Shiu, Hung, Chun-Ping, Chang, Jen-Shin, Song, Chia-Liang, Tai, Hua-Hao, Chiu, Wan-Ping, Hsieh, Yinchiu, Lin, Wan-Ling, Chung, Chun-Wei, Kuo, Chien-Huang, Wu, Cheng-Ming, Chu, Yen-Shih, Tung, Yu-Sheng, Chao, Kak-Shan, Shia
Publikováno v:
Journal of medicinal chemistry. 51(17)
Replacing the conventional pyrazole 5-aryl substituent of 1 (SR141716A) with the 2-thienyl moiety appended with an appropriate alkynyl unit, a novel class of 5-(5-alkynyl-2-thienyl)pyrazole derivatives, behaving as highly potent CB1 receptor antagoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33b31c9727608011e806ce56cb11373f
https://pubmed.ncbi.nlm.nih.gov/18712856
https://pubmed.ncbi.nlm.nih.gov/18712856
Autor:
Pei Jer Chen, Cheng Wen Lin, Chien-Chen Lai, Chang Hai Tsai, Kuan Hsun Lin, Lei Wan, Hua Hao Chiu, Fuu Jen Tsai
Publikováno v:
Febs Letters
Severe acute respiratory syndrome (SARS) has been globally reported. A novel coronavirus (CoV), SARS-CoV, was identified as the etiological agent of the disease. SARS-CoV 3C-like protease (3CLpro) mediates the proteolytic processing of replicase poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5d6950ddbb8eae0627614ccaedfd9f
https://pubmed.ncbi.nlm.nih.gov/15358553
https://pubmed.ncbi.nlm.nih.gov/15358553
Autor:
Ming-Shiu Hung, Yu-Sheng Chao, T D Suja, Jen-Shin Song, Min-Tsang Hsieh, Cheng-Ming Chu, Chun-Wei Kuo, Kak-Shan Shia, Hua-Hao Chiu
Publikováno v:
Organic & Biomolecular Chemistry. 6:3399
Based on the bioisosteric replacement of the pyrazole C3-carboxamide of rimonabant with a 5-alkyl oxadiazole ring, a novel class of oxadiazole derivatives with promising biological activity towards CB1 receptors was discovered. Among them, compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32f2f196839d104aee9d0d840c92b18
https://doi.org/10.1039/b807648k
https://doi.org/10.1039/b807648k