Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hua Hua Tong"'
Autor:
Hua Hua Tong, Garrett Lambert, Yong Xing Li, Joshua M Thurman, Gregory L Stahl, Kelsey Douthitt, Caitlin Clancy, Yujuan He, Andrew S Bowman
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95160 (2014)
There is considerable evidence that influenza A virus (IAV) promotes adherence, colonization, and superinfection by S. pneumoniae (Spn) and contributes to the pathogenesis of otitis media (OM). The complement system is a critical innate immune defens
Externí odkaz:
https://doaj.org/article/12e288f32b2443a889194c0c041d79a3
Publikováno v:
International Journal of Pediatric Otorhinolaryngology. 72:1183-1191
We have previously demonstrated that the disruptions of nontypeable Haemophilus influenzae (NTHi) lipooligosaccharide (LOS) htrB and rfaD genes may play a role in the pathogenesis of otitis media (OM). The purpose of this study was to determine wheth
Publikováno v:
FEMS Microbiology Letters. 253:151-154
Sortase A (SrtA) is required to anchor neuraminidase, beta-galactosidase, and possibly other LPXTG motif proteins to the pneumococcal cell surface. We examined the role of SrtA in Streptococcus pneumoniae nasopharyngeal (NP) colonization in the chinc
Publikováno v:
Microbial Pathogenesis. 31:309-317
Six different lectin probes were used to examine alterations of the cell surface carbohydrates in the chinchilla eustachian tube (ET) lumen subsequent to the intranasal (i.n.) challenge with the Streptococcus pneumoniae parent strain, D39, or its iso
Publikováno v:
Microbial Pathogenesis. 26:111-119
The adherence of Streptococcus pneumoniae (Spn) otitis media-associated serotypes 3, 6A and 14 to ciliated chinchilla respiratory epithelium was investigated using a whole organ perfusion technique. We demonstrated that Spn adhere to chinchilla trach
Publikováno v:
Environmental and Molecular Mutagenesis. 29:168-179
O6-Alkylguanine-DNA alkyltransferase (AGT) is responsible for repairing the O6-alkylguanine lesion in DNA. There is wide variation in the levels of AGT between organ and cell types, which appears to correlate with cell and tissue type sensitivity to
Publikováno v:
Microbial pathogenesis. 37(4)
Influenza A virus infection plays a significant role in the pathogenesis of Streptococcus pneumoniae-induced acute otitis media in children. An understanding of how influenza A virus modulates host cellular responses is critically important in effort
Publikováno v:
Acta oto-laryngologica. 122(4)
The trachea whole organ perfusion technique was used to study the effect of the disruption of the Streptococcus pneumoniae neuraminidase nanA gene on bacterial adherence and alteration of the carbohydrate surface structures of respiratory epithelial
Publikováno v:
Acta oto-laryngologica. 121(1)
Hypersecretion of mucin is a common feature of chronic and mucoid otitis media which may play an important role in hearing loss. The mechanisms controlling mucin secretion in the middle ear are not completely understood. Our reverse transcriptase-pol
Publikováno v:
The Annals of otology, rhinology, and laryngology. 109(11)
Considerable evidence has implicated respiratory tract virus potentiation of bacterial adherence, colonization, and superinfection as a significant factor contributing to the pathogenesis of otitis media (OM). Influenza A and B viruses, adenovirus, a