Zobrazeno 1 - 10
of 1 105
pro vyhledávání: '"Hua Gan"'
Autor:
Lu Zhang, Maoqing Tian, Meng Zhang, Chen Li, Xiaofei Wang, Yuyu Long, Yujuan Wang, Jijia Hu, Cheng Chen, Xinghua Chen, Wei Liang, Guohua Ding, Hua Gan, Lunzhi Liu, Huiming Wang
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Renal tubular epithelial cells (TECs) undergo an energy‐related metabolic shift from fatty acid oxidation to glycolysis during chronic kidney disease (CKD) progression. However, the mechanisms underlying this burst of glycolysis remain unc
Externí odkaz:
https://doaj.org/article/4faac6f41a284d149ea4b02b75e24f68
Autor:
Wenzhi Hao, Qingyu Ma, Lu Wang, Naijun Yuan, Hua Gan, Liangliang He, Xiaojuan Li, Junqing Huang, Jiaxu Chen
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-25 (2024)
Abstract Background Remodeling eubiosis of the gut microenvironment may contribute to preventing the occurrence and development of depression. Mounting experimental evidence has shown that complement C3 signaling is associated with the pathogenesis o
Externí odkaz:
https://doaj.org/article/fe8c6c6ae0f84bfcac52e1a5db989919
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Dyslipidemia is the most prevalent independent risk factor for patients with chronic kidney disease (CKD). Lipid-induced NLRP3 inflammasome activation in kidney-resident cells exacerbates renal injury by causing sterile inflammation. Nuclear factor e
Externí odkaz:
https://doaj.org/article/fb1aca208c624d1d9d1bdfbddf16780e
Publikováno v:
Pharmacological Research, Vol 202, Iss , Pp 107112- (2024)
Depression is a common disease that affects physical and mental health and imposes a considerable burden on afflicted individuals and their families worldwide. Depression is associated with a high rate of disability and suicide. It causes a severe de
Externí odkaz:
https://doaj.org/article/6ef6d638917646e3878bc45715af0354
Publikováno v:
Renal Failure, Vol 45, Iss 2 (2023)
Objective This study investigated the role of the P2Y12 receptor in autogenous arteriovenous fistula (AVF) failure resulting from stenosis.Methods Stenotic venous tissues and blood samples were obtained from patients with end-stage renal disease (ESR
Externí odkaz:
https://doaj.org/article/78f1a7faf75b4cf1bc31fba3cc2a9984
Publikováno v:
Renal Failure, Vol 45, Iss 1 (2023)
AbstractObjectives Recent evidence suggested that long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) play critical roles in the pathogenesis of vascular calcification (VC). In this study, we tried to explore the expression and role of a lncRNA, i.
Externí odkaz:
https://doaj.org/article/12411836febc44b6a7cdd3d357aec627
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundPhysicians usually consider that sodium bicarbonate (SB) infusion can be used for metabolic acidosis; however, there is little evidence available to assess its effect on hospital mortality in large AKI cohorts. Here, we investigated the eff
Externí odkaz:
https://doaj.org/article/57bab8e5291e41c0962b72b287688413
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Objective: To provide insights into the diagnosis and therapy of SA-AKI via ferroptosis genes.Methods: Based on three datasets (GSE57065, GSE30718, and GSE53771), we used weighted co-expression network analysis to identify the key regulators of SA-AK
Externí odkaz:
https://doaj.org/article/1e09949f4cd048a695bf57e9dd02ab0b
Autor:
Xinyi Yu, Liqun Chen, Ke Wu, Shujuan Yan, Ruyi Zhang, Chen Zhao, Zongyue Zeng, Yi Shu, Shifeng Huang, Jiayan Lei, Xiaojuan Ji, Chengfu Yuan, Linghuan Zhang, Yixiao Feng, Wei Liu, Bo Huang, Bo Zhang, Wenping Luo, Xi Wang, Bo Liu, Rex C. Haydon, Hue H. Luu, Tong-Chuan He, Hua Gan
Publikováno v:
Genes and Diseases, Vol 10, Iss 2, Pp 630-631 (2023)
Externí odkaz:
https://doaj.org/article/b38baf437754418e91eb252e0744061e
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 18 (2022)
Background Clinically, myocardial fibrosis is one of the most common complications caused by chronic kidney disease (CKD). However, the potential mechanisms of CKD‐induced myocardial fibrosis have not been clarified. Methods and Results In our in v
Externí odkaz:
https://doaj.org/article/28c047bf3bcc43a08d5cba7615ec9b33