Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hua‐Lan Wu"'
Autor:
Jian Liu, Hao Chen, Shuang‐Hu Wang, Quan Zhou, Pei‐Wu Geng, Yun‐Fang Zhou, Hua‐Lan Wu, Hai‐Feng Shi, Fang Wang, Jie‐Fu Yang, Jian‐Ping Cai, Da‐Peng Dai
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 1, Pp n/a-n/a (2021)
Abstract Cytochrome P450 2C9 (CYP2C9) is one of the most important drugs metabolizing enzymes and accounts for the metabolism of about 13%–17% of clinical drugs. Like other members in CYP2 family, CYP2C9 gene exhibits great genetic polymorphism amo
Externí odkaz:
https://doaj.org/article/eccf81e4a97a46aab0c14e33eab9a56f
Autor:
Hua-Lan Wu, Xinlong Zhao, Jiefu Yang, Jia Chong, Anxu Zhao, Da-Peng Dai, You Lü, Dongxu Wang, Hao Chen, Ruoyun Yin
Publikováno v:
Pharmacogenomics. 21:1021-1031
Aim: Gene polymorphisms are critical in warfarin dosing variation. Here, the role of rare CYP2C9 alleles on warfarin doses in Chinese Han patients was investigated. Methods: A retrospective study recruited 681 warfarin treated atrial fibrillation pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb2257b7b18976068aa99f5110826eb2
https://doi.org/10.2217/pgs-2020-0051
https://doi.org/10.2217/pgs-2020-0051
Autor:
Da-Peng Dai, Hua-Lan Wu, Hui Jiang, Hao Chen, Quan Zhou, Junpeng Liu, Feifei Chen, Jia Chong, Shuanghu Wang, Jiefu Yang, Yunfang Zhou, Minghui Du, You Lü
Publikováno v:
Pharmaceutical Biology, Vol 58, Iss 1, Pp 630-635 (2020)
Pharmaceutical Biology
article-version (VoR) Version of Record
Pharmaceutical Biology
article-version (VoR) Version of Record
Context Rivaroxaban and ticagrelor are two common drugs for the treatment of atrial fibrillation and acute coronary syndrome. However, the drug–drug interaction between them is still unknown. Objective To investigate the effects of ticagrelor on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c690d8af0bb753ba2ceec522c9ffc852
https://doaj.org/article/6e8c3613c83c425c847cb050c63cc770
https://doaj.org/article/6e8c3613c83c425c847cb050c63cc770
Autor:
Da‐Peng Dai, Jiefu Yang, Shuanghu Wang, Fang‐Ling Zhao, Hao Chen, Quan Zhou, Jia Chong, Yunfang Zhou, Haifeng Shi, Peiwu Geng, Hua-Lan Wu, Fang Wang
Publikováno v:
Pharmacology Research & Perspectives
Food–drug interactions are reported to have some impacts on the pharmacokinetics and pharmacodynamics of various oral drugs. To better understand the effects of naringenin, one natural product in many fruits, on the pharmacokinetics of rivaroxaban,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4fd5103f1afc4be548bb3722fbb021e
http://europepmc.org/articles/PMC8099043
http://europepmc.org/articles/PMC8099043
Autor:
You Lü, Peiwu Geng, Jiefu Yang, Shuanghu Wang, Jian Liu, Shan Zhou, Hua-Lan Wu, Jia Chong, Dapeng Dai, Hao Chen, Jian-Ping Cai, Quan Zhou
Publikováno v:
Chemico-biological interactions. 327
Warfarin is the most commonly used anticoagulant in the clinical treatment of thromboembolic diseases. The dose of warfarin varies significantly within populations, and the dose is closely related to the genetic polymorphisms of the CYP2C9 and VKORC1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b57a358a08e45e69d272861c30e1c293
https://pubmed.ncbi.nlm.nih.gov/32531309
https://pubmed.ncbi.nlm.nih.gov/32531309