Zobrazeno 1 - 10
of 1 720
pro vyhledávání: '"Hu ZHOU"'
Autor:
Jing Yu, Xiuqi Gui, Yunhao Zou, Qian Liu, Zhicheng Yang, Jusheng An, Xuan Guo, Kaihua Wang, Jiaming Guo, Manni Huang, Shuhan Zhou, Jing Zuo, Yimin Chen, Lu Deng, Guangwen Yuan, Ning Li, Yan Song, Jia Jia, Jia Zeng, Yuxi Zhao, Xianming Liu, Xiaoxian Du, Yansheng Liu, Pei Wang, Bing Zhang, Li Ding, Ana I. Robles, Henry Rodriguez, Hu Zhou, Zhen Shao, Lingying Wu, Daming Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Although the incidence of cervical cancer (CC) has been reduced in high-income countries due to human papillomavirus (HPV) vaccination and screening strategies, it remains a significant public health issue that poses a threat to women’s he
Externí odkaz:
https://doaj.org/article/59efc1d3d966428eb81d5a48b4ce3781
Publikováno v:
Zhongguo Jianchuan Yanjiu, Vol 19, Iss 5, Pp 122-130 (2024)
ObjectivesThis study proposes a structural strain test method for investigating the buckling pressure of a composite shell in a high hydrostatic pressure water environment and the effects of different initial defects. MethodsA high hydrostatic pressu
Externí odkaz:
https://doaj.org/article/ace41957da7d43d3abfe685967394ae1
Autor:
Xiuqi Gui, Jing Huang, Linjie Ruan, Yanjun Wu, Xuan Guo, Ruifang Cao, Shuhan Zhou, Fengxiang Tan, Hongwen Zhu, Mushan Li, Guoqing Zhang, Hu Zhou, Lixing Zhan, Xin Liu, Shiqi Tu, Zhen Shao
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-30 (2024)
Abstract Isobaric labeling-based mass spectrometry (ILMS) has been widely used to quantify, on a proteome-wide scale, the relative protein abundance in different biological conditions. However, large-scale ILMS data sets typically involve multiple ru
Externí odkaz:
https://doaj.org/article/fe7c834f206441fa942fc533108154fe
Publikováno v:
Noise and Health, Vol 26, Iss 122, Pp 396-402 (2024)
The developing brain is significantly affected by long-term exposure to noise at an early age, leading to functional disorders such as learning and memory impairments. Gastrodin (GAS), a natural organic compound, is an extraction of phenolic glycosid
Externí odkaz:
https://doaj.org/article/fc98e3dabfd841d9b84c91fb361edaf9
Autor:
Sanfeng Dong, Hui Huang, Jintian Li, Xiaomei Li, Samuel Jacob Bunu, Yun Yang, Yong Zhang, Qi Jia, Zhijian Xu, Yingxia Li, Hu Zhou, Bo Li, Weiliang Zhu
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Multi-functional cysteine-targeting covalent warheads possess significant therapeutic potential in medicinal chemistry and chemical biology. Herein, we present novel unsaturated and asymmetric ketone (oxazolinosene) scaffolds that selectivel
Externí odkaz:
https://doaj.org/article/12c83f9003c94331982b31a3e3224e5e
Autor:
Tao Zhang, Zilu Pan, Jing Gao, Qingqing Wu, Gang Bai, Yan Li, Linjiang Tong, Fang Feng, Mengzhen Lai, Yingqiang Liu, Peiran Song, Yi Ning, Haotian Tang, Wen Luo, Yi Chen, Yan Fang, Hui Zhang, Qiupei Liu, Yudi Zhang, Hua Wang, Zhiwei Chen, Meiyu Geng, Hongbin Ji, Guilong Zhao, Hu Zhou, Jian Ding, Hua Xie
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Third-generation EGFR tyrosine kinase inhibitors (TKIs), exemplified by osimertinib, have demonstrated promising clinical efficacy in the treatment of non-small cell lung cancer (NSCLC). Our previous work has identified ASK120067 as a novel
Externí odkaz:
https://doaj.org/article/ac02c35257c841fd98b81773c3a5ce01
Autor:
Fanwei Huang, Liang He, Wei Li, Xiaoyuan Huang, Tao Zhang, Munawaer Muaibati, Hu Zhou, Shimin Chen, Wenhui Yang, Fan Yang, Liang Zhuang, Ting Hu
Publikováno v:
Infectious Agents and Cancer, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background This study aimed to investigate whether persistent human papillomavirus integration at the same loci (PHISL) before and after treatment can predict recurrent/residual disease in women with CIN2-3. Methods A total of 151 CIN2-3 wom
Externí odkaz:
https://doaj.org/article/310281b570ed45179a2af525e10b8cd5
Autor:
Boning Niu, Tianyi Tian, Lu Wang, Yinmei Tian, Tian Tian, Yuanyuan Guo, Hu Zhou, Zhiping Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3711-3729 (2024)
SMAD4 deficiency in colorectal cancer (CRC) is highly correlated with liver metastasis and high mortality, yet there are few effective precision therapies available. Here, we show that CCR1+-granulocytic myeloid-derived suppressor cells (G-MDSCs) are
Externí odkaz:
https://doaj.org/article/8b51300b9e334222810942d71f64f05f
Publikováno v:
Zhongguo Jianchuan Yanjiu, Vol 19, Iss 3, Pp 86-95 (2024)
ObjectiveThis paper aims to reveal the influence of the afterburning effect of explosive materials in confined space explosion. MethodsA series of TNT blast tests are performed in a confined cabin filled with two different atmospheres, air and nitrog
Externí odkaz:
https://doaj.org/article/98f309dc368f4308986a62b76d81769c
Autor:
Shirong Li, Wangxiao Xia, Bin Sun, Weiyan Peng, Dong Yang, Jing Gao, Shuai He, Hua Yang, Yongjie Zhu, Hu Zhou, Tingxiu Xiang, Qingpeng Kong, Xudong Zhao
Publikováno v:
Genes and Diseases, Vol 11, Iss 6, Pp 101123- (2024)
FK506-binding protein 9 (FKBP9) is involved in tumor malignancy by resistance to endoplasmic reticulum (ER) stress, and the up-regulation of FKBP9 is associated with patients' poor prognosis. The current knowledge of the molecular mechanisms is still
Externí odkaz:
https://doaj.org/article/d59738ad010d48d8b2c5ff30b389a16f