Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Hu Lin Jiang"'
Autor:
Shobha Regmi, Shiva Pathak, Dinesh Chaudhary, Jong Oh Kim, Joo-Won Nam, Hyung-Sik Kim, Hu-Lin Jiang, Dongryeol Ryu, Jong-Hyuk Sung, Simmyung Yook, Jee-Heon Jeong
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Background Stem cell therapy is a promising alternative for inflammatory diseases and tissue injury treatment. Exogenous delivery of mesenchymal stem cells is associated with instant blood-mediated inflammatory reactions, mechanical stress d
Externí odkaz:
https://doaj.org/article/f36d3fe33ba34887bba91935c167f7da
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Non-small cell lung cancer (NSCLC) shows high drug resistance and leads to low survival due to the high level of mutated Tumor Protein p53 (TP53). Cisplatin is a first-line treatment option for NSCLC, and the p53 mutation is a major factor i
Externí odkaz:
https://doaj.org/article/1e69bc703a6140a1a2e5af77e5e2a22a
Autor:
Liang Qi, Bo‐Wen Duan, Hui Wang, Yan‐Jun Liu, Han Han, Meng‐Meng Han, Lei Xing, Hu‐Lin Jiang, Stephen J. Pandol, Ling Li
Publikováno v:
Advanced Science, Vol 11, Iss 19, Pp n/a-n/a (2024)
Abstract Pancreatic fibrosis (PF) is primarily characterized by aberrant production and degradation modes of extracellular matrix (ECM) components, resulting from the activation of pancreatic stellate cells (PSCs) and the pathological cross‐linking
Externí odkaz:
https://doaj.org/article/f55b8429f5cf4eb486e2d2cbd8cea183
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 415-431 (2023)
Pulmonary fibrosis (PF) is an interstitial lung disease with complex pathological mechanism, and there is currently a lack of therapeutics that can heal it completely. Using gene therapy with drugs provides promising therapeutic strategies for synerg
Externí odkaz:
https://doaj.org/article/e95649a27d964aaaa9d1c325aca8a490
Autor:
Bo‐Wen Duan, Yan‐Jun Liu, Xue‐Na Li, Meng‐Meng Han, Hao‐Yuan Yu, He‐Yuan Hong, Ling‐Feng Zhang, Lei Xing, Hu‐Lin Jiang
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract In advanced liver fibrosis (LF), macrophages maintain the inflammatory environment in the liver and accelerate LF deterioration by secreting proinflammatory cytokines. However, there is still no effective strategy to regulate macrophages bec
Externí odkaz:
https://doaj.org/article/b6200080e8964a80b3cfa51699c19533
Autor:
Ying Sun, Lei Xing, Jun Luo, Ming‐Tao Yu, Xiao‐Jie Wang, Yi Wang, Tian‐Jiao Zhou, Hu‐Lin Jiang
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Circulating tumor cells (CTCs) and tumor‐derived exosomes (TDEs) play an irreplaceable role in the metastatic cascade and preventing them from reaching distant organs via blood circulation helps to reduce the probability of cancer recurren
Externí odkaz:
https://doaj.org/article/27d384d194ee4d5b966fef4f35b190d5
Autor:
Hua Jin, Yoonjeong Jang, Nian Cheng, Qing Li, Peng-Fei Cui, Zhi-Wei Zhou, Hu-Lin Jiang, Myung-Haing Cho, Kenneth D. Westover, Qun-You Tan, Cheng-Xiong Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Abstract Background miRNAs play crucial role in the progression of K-Ras-mutated nonsmall cell lung cancer (NSCLC). However, most studies have focused on miRNAs that target K-Ras. Here, we investigated miRNAs regulated by mutant K-Ras and their funct
Externí odkaz:
https://doaj.org/article/7b3a3c05b70c4aa2aaa96faea1c11380
Autor:
Tian-Tian Zhao, Tian-Jiao Zhou, Chen Zhang, Ying-Xuan Liu, Wen-Jia Wang, Chengjun Li, Lei Xing, Hu-Lin Jiang
Publikováno v:
Molecular Pharmaceutics. 20:2612-2623
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eda65004a4a47c859010b71251a45db3
https://doi.org/10.1021/acs.molpharmaceut.3c00068
https://doi.org/10.1021/acs.molpharmaceut.3c00068
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-10 (2018)
Abstract Heat shock protein 90 (Hsp90) is a critical molecular chaperone protein that regulates the folding, maturation, and stability of a wide variety of proteins. In recent years, the development of Hsp90-directed inhibitors has grown rapidly, and
Externí odkaz:
https://doaj.org/article/2107bca6f9494db5b9cf96b33a96cb65
Autor:
Ming-Yuan, Yang, Yi-Jun, Lin, Meng-Meng, Han, Yu-Yang, Bi, Xing-Yue, He, Lei, Xing, Jee-Heon, Jeong, Tian-Jiao, Zhou, Hu-Lin, Jiang
Publikováno v:
Journal of Controlled Release. 351:623-637
Idiopathic pulmonary fibrosis (IPF) is a fibrotic interstitial lung disease in which collagen progressively deposits in the supporting framework of the lungs. The pathological collagen creates a recalcitrant barrier in mesenchyme for drug penetration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38d650798ca358496fdc0d78126f41e
https://doi.org/10.1016/j.jconrel.2022.09.054
https://doi.org/10.1016/j.jconrel.2022.09.054