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pro vyhledávání: '"Htet Ng"'
Autor:
Tuan Nguyen, Sai Li, Jeremy T-H Chang, John W. Watters, Htet Ng, Adewola Osunsade, Yael David, Shixin Liu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here the authors used single-molecule imaging and manipulation to study the mechanical effects of transcription factor Sox2 co-condensation with DNA and chromatin. They found that Sox2 condensates exert a high level of mechanical stress on DNA, but t
Externí odkaz:
https://doaj.org/article/a5fc41cecb574669a410977790cd6293
Autor:
Tuan Nguyen, Sai Li, Jeremy T-H Chang, John W. Watters, Htet Ng, Adewola Osunsade, Yael David, Shixin Liu
Publikováno v:
Nature communications. 13(1)
Formation of biomolecular condensates constitutes an emerging mechanism for transcriptional regulation. Recent studies suggest that the co-condensation between transcription factors (TFs) and DNA can generate mechanical forces driving genome rearrang