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Akademický článek

A chimeric nuclease substitutes a phage CRISPR-Cas system to provide sequence-specific immunity against subviral parasites

Autor: Zachary K Barth, Maria HT Nguyen, Kimberley D Seed

Publikováno v: eLife, Vol 10 (2021)

Mobile genetic elements, elements that can move horizontally between genomes, have profound effects on their host's fitness. The phage-inducible chromosomal island-like element (PLE) is a mobile element that integrates into the chromosome of Vibrio c

Externí odkaz: https://doaj.org/article/ac909c46f0ff45d68da1fa93f65ade29

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Meshfree simulation of progressive damage in composite laminates using discrete element analysis

Autor: Johannes Reiner, Nhu HT Nguyen

Publikováno v: Journal of Composite Materials. 57:1135-1148

This study presents a Discrete Element Method (DEM) for a meshfree progressive failure analysis of IM7/8552 carbon fibre reinforced polymer laminates at the macroscale. By implementing a cohesive contact model to describe progressive damage, experime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::032c7cbbf0f8c78308ce541191d4594c
https://doi.org/10.1177/00219983221149792

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A phage weaponizes a satellite recombinase to subvert viral restriction

Autor: Maria HT Nguyen, Zoe Netter, Angus Angermeyer, Kimberley D. Seed

Publikováno v: Nucleic acids research, vol 50, iss 19

Bacteria can acquire mobile genetic elements (MGEs) to combat infection by viruses (phages). Satellite viruses, including the PLEs (phage-inducible chromosomal island-like elements) in epidemic Vibrio cholerae, are MGEs that restrict phage replicatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e793891e7fc9acf2c7cd4acb1e41020b
https://doi.org/10.1093/nar/gkac845

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Akademický článek

Carvedilol improves glucose tolerance and insulin sensitivity in treatment of adrenergic overdrive in high fat diet-induced obesity in mice.

Autor: Linh V Nguyen, Quang V Ta, Thao B Dang, Phu H Nguyen, Thach Nguyen, Thi Van Huyen Pham, Trang Ht Nguyen, Stephen Baker, Trung Le Tran, Dong Joo Yang, Ki Woo Kim, Khanh V Doan

Publikováno v: PLoS ONE, Vol 14, Iss 11, p e0224674 (2019)

Catecholamine excess reflecting an adrenergic overdrive of the sympathetic nervous system (SNS) has been proposed to link to hyperleptinemia in obesity and may contribute to the development of metabolic disorders. However, relationship between the ca

Externí odkaz: https://doaj.org/article/c9a1864045ae49d3b550fbfdb619acf8

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240 Risks and benefits of systematic lymphadenectomy during interval debulking surgery for advanced high grade serous ovarian cancer

Autor: MA Le Frere Belda, Louise Benoit, A S Bats, Nicolas Delanoy, HT Nguyen Xuan, J Zerbib, Enrica Bentivegna, Henri Azaïs, Laure Fournier, Meriem Koual

Publikováno v: Ovarian cancer.

Introduction/Background* Recent findings have suggested that lymphadenectomy during primary cytoreductive surgery (CRS) in patients with ovarian cancer was not associated with an improve in survival, at the expense of a high morbidity. The aim of our

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::777b668e0cdb7da24a7a70e83d0d38a4
https://doi.org/10.1136/ijgc-2021-esgo.365

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236 What can we learn from the 10 mm lymph node size cut-off on the CT in advanced ovarian cancer at the time of interval debulking surgery?

Autor: J Zerbib, Henri Azaïs, HT Nguyen Xuan, Laure Fournier, A S Bats, Louise Benoit, Nicolas Delanoy, Enrica Bentivegna, Meriem Koual, MA Le Frere Belda

Publikováno v: Ovarian cancer.

Introduction/Background* The benefit of a systematic lymphadenectomy is still debated in patients undergoing neo-adjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) in ovarian cancer (OC). The objective of this study was to eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::458cdcde1367dafaf9cb14056809b17e
https://doi.org/10.1136/ijgc-2021-esgo.363

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