Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hsun Lun A. Huang"'
Publikováno v:
British Journal of Clinical Pharmacology. 68:381-385
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT? • Sotrastaurin is an investigational protein kinase C inhibitor. This represents a new mechanism of action for immunosuppression to prevent acute rejection after organ transplantation. In vitro experiments
Autor:
Gilbert Lefèvre, Françoise Pommier, Silke Appel-Dingemanse, Heinz Schmidli, M. T. Leibowitz, Albert Enz, Steve Maton, S. S. Jhee, Hsun-Lun Aaron Huang, Larry Ereshefsky, Greg Sedek
Publikováno v:
Clinical Pharmacology & Therapeutics. 83:106-114
A transdermal patch has been developed for the cholinesterase inhibitor rivastigmine. This study investigated the pharmacokinetics and pharmacodynamics of rivastigmine and NAP226-90, and compared drug exposure between patch and capsule administration
Autor:
Billy Amzal, Francois Mercier, Gilbert Lefèvre, Silke Appel-Dingemanse, Heinz Schmidli, Hsun-Lun Aaron Huang
Publikováno v:
Current Medical Research and Opinion. 23:3199-3204
The rivastigmine transdermal patch is the first transdermal treatment for Alzheimer's disease (AD) and dementia associated with Parkinson's disease. The objective of this study was to evaluate the pharmacokinetics of rivastigmine following transderma
Autor:
Hsun Lun A. Huang, Hrayr S. Karagueuzian, Carlos Blanche, Alfredo Trento, Wen Cheng, Robert M. Kass, Rahul N. Doshi, Peng Sheng Chen, Tsu Juey Wu, C. Thomas Peter
Publikováno v:
Journal of Cardiovascular Electrophysiology. 13:571-577
Activations in Permanent Atrial Fibrillation.Introduction: Activation patterns during permanent atrial fibrillation (AF) in patients with organic heart diseases are unclear. Methods and Results: We studied six patients with permanent AF and organic h
Autor:
Chih Tai Ting, Tsu Juey Wu, Michael C. Fishbein, Masaaki Yashima, Hrayr S. Karagueuzian, James J.C. Ong, Rahul N. Doshi, Hsun Lun A. Huang, Peng Sheng Chen, Che Ming Chang
Publikováno v:
Circulation. 103:1157-1163
Background —In dogs, chronic rapid pacing may result in sustained atrial fibrillation (AF). However, activation patterns in pacing-induced sustained AF are unclear. Methods and Results —We induced sustained AF (>48 hours) in 6 dogs by rapid pacin
Autor:
James N. Weiss, Hrayr S. Karagueuzian, Gregory A. Fishbein, Shien-Fong Lin, Charles D. Swerdlow, Peng Sheng Chen, Olga Voroshilovsky, Zhilin Qu, Alan Garfinkel, Hsun Lun A. Huang, Toshihiko Ohara, Moon Hyoung Lee
Publikováno v:
Circulation. 102:1569-1574
Background —The mechanisms by which 60-Hz alternating current (AC) can induce ventricular fibrillation (VF) are unknown. Methods and Results —We studied 7 isolated perfused swine right ventricles in vitro. The action potential duration restitutio
Autor:
William P. Dole, Sujata Vaidyanathan, Hans Armin Dieterich, Yeh Cm, Marie-Noelle Bizot, Hsun-Lun Aaron Huang, Dan Howard
Publikováno v:
Current medical research and opinion. 24(9)
Aliskiren is a direct renin inhibitor approved for the treatment of hypertension. This study investigated the effects of aliskiren on the pharmacokinetics and pharmacodynamics of a single dose of acenocoumarol in healthy volunteers.This two-sequence,
Autor:
Greg Sedek, Gilbert Lefèvre, Hsun-Lun Aaron Huang, Beate Kiese, Marc Saltzman, Mitchell Rosenberg, Peter Fordham
Publikováno v:
Journal of clinical pharmacology. 47(4)
A patch formulation of rivastigmine, an inhibitor of acetylcholinesterase and butyrylcholinesterase, is under development. The current objective was to evaluate the pharmacokinetic profile and patch adhesiveness following application at the upper bac
Autor:
François Mercier, Gilbert Lefèvre, Hsun-Lun Aaron Huang, Heinz Schmidli, Billy Amzal, Silke Appel-Dingemanse
Publikováno v:
Current Medical Research & Opinion; Dec2007, Vol. 23 Issue 12, p3199-3204, 6p