Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hsueh-Fu Wu"'
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 102970- (2024)
Summary: Assessing the development and function of the sympathetic nervous system in diseases on a large scale is challenging. Here, we present a protocol to generate human pluripotent stem cell (hPSC)-derived postganglionic sympathetic neurons (symN
Externí odkaz:
https://doaj.org/article/94aea56badb84f178b2821f33c73839d
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 4, Pp 779-783 (2023)
Alzheimer’s disease is a neurodegenerative disease that affected over 6.5 million people in the United States in 2021, with this number expected to double in the next 40 years without any sort of treatment. Due to its heterogeneity and complexity,
Externí odkaz:
https://doaj.org/article/e39b2e6538fa4da2bee28d51b99a080a
Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models
Autor:
Hsueh-Fu Wu, Wenxin Yu, Kenyi Saito-Diaz, Chia-Wei Huang, Joseph Carey, Frances Lefcort, Gerald W. Hart, Hong-Xiang Liu, Nadja Zeltner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Sympathetic neurons are affected in familial dysautonomia, a rare disease associated with a mutation in ELP1, but the mechanisms are not fully understood. Here the authors show, using neurons derived from participants with familial dysauotnomia, that
Externí odkaz:
https://doaj.org/article/0aa61b6874b840a68056479fc501db76
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
O-GlcNAcylation is a post-translational modification (PTM) that regulates a wide range of cellular functions and has been associated with multiple metabolic diseases in various organs. The sympathetic nervous system (SNS) is the efferent portion of t
Externí odkaz:
https://doaj.org/article/d0edf94f88504e9db6a15704a368b4d2
Autor:
Chia‐Wei Huang, Nicholas C. Rust, Hsueh‐Fu Wu, Amelia Yin, Nadja Zeltner, Hang Yin, Gerald W. Hart
Publikováno v:
Alzheimer's & Dementia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ab2e3f45d89c1368d3371c1c9faf3f1
https://doi.org/10.1002/alz.13058
https://doi.org/10.1002/alz.13058
Publikováno v:
Neural regeneration research. 18(4)
Alzheimer's disease is a neurodegenerative disease that affected over 6.5 million people in the United States in 2021, with this number expected to double in the next 40 years without any sort of treatment. Due to its heterogeneity and complexity, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7954c564f77eff705458da59fd03823
https://pubmed.ncbi.nlm.nih.gov/36204837
https://pubmed.ncbi.nlm.nih.gov/36204837
Autor:
Olga Amaral, Enrico Bertini, José Bragança, Esra Cagavi, Claudia Compagnucci, Ana Duarte, Julian A. Gingold, Subhajit Giri, Mo-Fan Huang, Shilpa Iyer, Yoon-Young Jang, Dung-Fang Lee, Justin Lowenthal, Brigitte Malgrange, Fibi Meshrkey, Ryuji Morizane, Ozlem Mutlu Burnaz, Lon Kai Pang, Mezthly Pena, Raj R. Rao, Diogo Ribeiro, Renato Santos, Marco Tartaglia, Gordon F. Tomaselli, Tamara Traitteur, Leslie Tung, Heidi Ulrichs, Yichen Wang, Franklin D. West, Hsueh Fu Wu, Brenda Yang, Nadja Zeltner, Chengcheng Zhang, Ruiying Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e1f9cf3f4253c68cf9068ccd2b34f9
https://doi.org/10.1016/b978-0-323-85767-3.01002-1
https://doi.org/10.1016/b978-0-323-85767-3.01002-1
Familial dysautonomia (FD) is a rare neurodevelopmental and neurodegenerative disorder that affects the sympathetic nervous system. Patients harbor a mutation in ELP1 yet, how loss of Elp1 affects the function of symNs remains unresolved. Such an und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d60c1b5fdd9df37fa1b5f3ff77b14904
https://doi.org/10.21203/rs.3.rs-1024649/v1
https://doi.org/10.21203/rs.3.rs-1024649/v1
Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia models
Autor:
Hsueh-Fu Wu, Wenxin Yu, Kenyi Saito-Diaz, Chia-Wei Huang, Joseph Carey, Frances Lefcort, Gerald W. Hart, Hong-Xiang Liu, Nadja Zeltner
Publikováno v:
Nature communications. 13(1)
Familial dysautonomia (FD), a rare neurodevelopmental and neurodegenerative disorder affects the sympathetic and sensory nervous system. Although almost all patients harbor a mutation in ELP1, it remains unresolved exactly how function of sympathetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57a79623f67267848cd751701b10130
https://pubmed.ncbi.nlm.nih.gov/36396637
https://pubmed.ncbi.nlm.nih.gov/36396637