Zobrazeno 1 - 10
of 327
pro vyhledávání: '"Hsueh Fen Juan"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Interstitial lung disease (ILD) is the primary cause of mortality in systemic sclerosis (SSc), an autoimmune disease characterized by tissue fibrosis. SSc-related ILD (SSc-ILD) occurs more frequently in females aged 30–55 years,
Externí odkaz:
https://doaj.org/article/5f193c0c75cf4678a85082159fae9ecc
Autor:
Hsiao-Han Lin, Cheng-Wei Chang, Yu-Ting Liao, Shauh-Der Yeh, Hsiu-Ping Lin, Hui-Min Ho, Chantal Hoi-Yin Cheung, Hsueh-Fen Juan, Yi-Rong Chen, Yu-Wen Su, Li-Mei Chen, Tse-Hua Tan, Wen-Jye Lin
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract DUSP22, an atypical dual-specificity phosphatase enzyme, plays a significant role in regulating multiple kinase signaling pathways by dephosphorylation. Our study demonstrated that decreased DUSP22 expression is associated with shorter disea
Externí odkaz:
https://doaj.org/article/9070ec439dfa49ff8d34cbdafe135424
Autor:
Yi-Chun Kao, Yi-Wen Chang, Charles P. Lai, Nai-Wen Chang, Chen-Hao Huang, Chien-Sheng Chen, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstarct Ectopic ATP synthase on the plasma membrane (eATP synthase) has been found in various cancer types and is a potential target for cancer therapy. However, whether it provides a functional role in tumor progression remains unclear. Here, quant
Externí odkaz:
https://doaj.org/article/935dc631597d4e1bb53634e0a697807d
Autor:
Yi-Wen Chang, T. Tony Yang, Min-Chun Chen, Y-geh Liaw, Chieh-Fan Yin, Xiu-Qi Lin-Yan, Ting-Yu Huang, Jen-Tzu Hou, Yi-Hsuan Hung, Chia-Lang Hsu, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Ectopic ATP synthase complex (eATP synthase), located on cancer cell surface, has been reported to possess catalytic activity that facilitates the generation of ATP in the extracellular environment to establish a suitable microenvironment an
Externí odkaz:
https://doaj.org/article/722270eaa3034aba9f1695a66af0cee9
Autor:
Chiao-Hui Hsieh, Chen-Tsung Huang, Yi-Sheng Cheng, Chun-Hua Hsu, Wen-Ming Hsu, Yun-Hsien Chung, Yen-Lin Liu, Tsai-Shan Yang, Chia-Yu Chien, Yu-Hsuan Lee, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115429- (2023)
Neuroblastoma, a childhood cancer affecting the sympathetic nervous system, continues to challenge the development of potent treatments due to the limited availability of druggable targets for this aggressive illness. Recent investigations have uncov
Externí odkaz:
https://doaj.org/article/4b40b94a1f034bc0b617bd5fa477fa59
Autor:
Chiao-Yu Hsieh, Jian-Hung Wen, Shih-Ming Lin, Tzu-Yang Tseng, Jia-Hsin Huang, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 150-157 (2023)
Single-cell RNA sequencing (scRNA-seq) technology allows massively parallel characterization of thousands of cells at the transcriptome level. scRNA-seq is emerging as an important tool to investigate the cellular components and their interactions in
Externí odkaz:
https://doaj.org/article/f9238b3f09bd48209dd6cc3371a95b8e
Autor:
Chia-Lang Hsu, Chieh-Fan Yin, Yi-Wen Chang, Ya-Chih Fan, Shih-Han Lin, Yu-Ching Wu, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-10 (2022)
Abstract The small nucleolar RNA host gene 1 (SNHG1) is a novel oncogenic long non-coding RNA (lncRNA) aberrantly expressed in different tumor types. We previously found highly expressed SNHG1 was associated with poor prognosis and MYCN status in neu
Externí odkaz:
https://doaj.org/article/c47c26a408c14356b4e2e7bbad30aa47
Autor:
Wen-Hsuan Yu, Chia-Lang Hsu, Chen-Ching Lin, Yen-Jen Oyang, Hsueh-Fen Juan, Hsuan-Cheng Huang
Publikováno v:
BMC Medical Genomics, Vol 14, Iss S3, Pp 1-12 (2022)
Abstract Background Recently, non-coding RNAs are of growing interest, and more scientists attach importance to research on their functions. Long non-coding RNAs (lncRNAs) are defined as non-protein coding transcripts longer than 200 nucleotides. We
Externí odkaz:
https://doaj.org/article/237fff6bc81242afba8cca2ad1fd089f
Publikováno v:
BMC Medical Genomics, Vol 14, Iss S3, Pp 1-15 (2021)
Abstract Background Increasing amount of long non-coding RNAs (lncRNAs) have been found involving in many biological processes and played salient roles in cancers. However, up until recently, functions of most lncRNAs in lung cancer have not been ful
Externí odkaz:
https://doaj.org/article/68951ebfe7914f829bff3b00b6595ec7
Publikováno v:
BMC Genomics, Vol 22, Iss S3, Pp 1-8 (2021)
Abstract Background A new class of regulatory elements called super-enhancers, comprised of multiple neighboring enhancers, have recently been reported to be the key transcriptional drivers of cellular, developmental, and disease states. Results Here
Externí odkaz:
https://doaj.org/article/984823a71155488da684c57a2649353d