Association of IgG1 Antibody Clearance with FcγRIIA Polymorphism and Platelet Count in Infliximab-Treated Patients

Autor: Gilles, Thibault, Gilles, Paintaud, Hsueh Cheng, Sung, Laurie, Lajoie, Edouard, Louis, The Getaid, Celine, Desvignes, Hervé, Watier, Valérie, Gouilleux-Gruart, David, Ternant

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 6051, p 6051 (2021)

The FcγRIIA/CD32A is mainly expressed on platelets, myeloid and several endothelial cells. Its affinity is considered insufficient for allowing significant binding of monomeric IgG, while its H131R polymorphism (histidine >
arginine at positi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c2acb1ffb913b634ed36a566a2048b42

ADAM17-Mediated Shedding of FcγRIIIA on Human NK Cells: Identification of the Cleavage Site and Relationship with Activation

Autor: Thierry Moreau, Hsueh Cheng Sung, Laurie Lajoie, Nicolas Congy-Jolivet, Valérie Gouilleux-Gruart, Frank Peiretti, Béatrice Clémenceau, Henri Vié, Elodie Sicard, Armelle Bolzec, Gilles Thibault

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2014, 192 (2), pp.741-751. ⟨10.4049/jimmunol.1301024⟩

FcγRIIIA/CD16A, the low-affinity receptor for the IgG Fc portion expressed on human CD56dim NK cells and involved in Ab-dependent cell cytotoxicity, is shed upon NK cell activation. We found that recombinant a disintegrin and metalloprotease (ADAM)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23e45b428473bd0a570dcd21540f5a7
https://hal.archives-ouvertes.fr/hal-02389220

Transcriptional regulation during CD8 T-cell immune responses

Autor: Ivana, Munitic, César, Evaristo, Hsueh Cheng, Sung, Benedita, Rocha

Publikováno v: Advances in experimental medicine and biology. 684

Naïve CD8 T cells differentiate in response to antigen stimulation. They acquire the capacity to express multiple effector molecules and mediate effector functions that contribute to infection control. Once antigen loads are reduced they revert prog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3922dc911d86b63f7722e750bd7f92e7
https://pubmed.ncbi.nlm.nih.gov/20795537

Repeated decrease of CD4+ T-cell counts in patients with rheumatoid arthritis over multiple cycles of rituximab treatment.

Autor: Lavielle, Matthieu, Mulleman, Denis, Goupille, Philippe, Bahuaud, Clément, Hsueh Cheng Sung, Watier, Hervé, Thibault, Gilles

Publikováno v: Arthritis Research & Therapy; 10/28/2016, Vol. 18, p1-9, 9p, 2 Charts, 6 Graphs

Cognate antigen stimulation generates potent CD8+ inflammatory effector cells.

Autor: Hsueh-Cheng Sung, Lemos, Sara, Ribeiro-Santos, Patricia, Kozryska, Kateryna, Vasseur, Florence, Legrand, Agnes, Charbit, Alain, Rocha, Benedita, Evaristo, Cesar

Publikováno v: Frontiers in Immunology; Nov2013, Vol. 4, preceding p1-16, 26p