Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Hsuan-Yu Peng"'
Autor:
Yu‐Ting Chang, Hsuan‐Yu Peng, Chun‐Mei Hu, Sui‐Chih Tien, Yi‐Ing Chen, Yung‐Ming Jeng, Ming‐Chu Chang
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1628-1647 (2023)
Cancer‐associated fibroblasts (CAFs), a major component of the tumor microenvironment (TME) in pancreatic ductal adenocarcinoma (PDAC), play an important role in tumorigenesis, metastasis, and chemoresistance. Tumor‐derived small extracellular ve
Externí odkaz:
https://doaj.org/article/da4eb509dd15471e9d95bcf9706e728d
Autor:
Hsuan-Yu Peng, Jenn-Ren Hsiao, Sung-Tau Chou, Yuan-Ming Hsu, Guan-Hsun Wu, Yi-Shing Shieh, Shine-Gwo Shiah
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 11, Pp 554-565 (2020)
The cytokine-inducible Src homology 2-containing protein (CISH) is an endogenous suppressors of signal transduction and activator of transcription (STAT) and acts as a key negative regulator of inflammatory cytokine responses. Downregulation of CISH
Externí odkaz:
https://doaj.org/article/9267c7d697d44d3a92d2e4a73c84f69e
Autor:
Shine-Gwo Shiah, Jenn-Ren Hsiao, Hsiao-Ju Chang, Yuan-Ming Hsu, Guan-Hsun Wu, Hsuan-Yu Peng, Sung-Tau Chou, Ching-Chuan Kuo, Jang-Yang Chang
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-13 (2020)
Abstract Background Epigenetic silencing of retinoic acid (RA) signaling-related genes have been linked with the pathogenesis and clinical outcome in oral squamous cell carcinoma (OSCC) carcinogenesis. However, the precise mechanisms underlying the a
Externí odkaz:
https://doaj.org/article/8eb2b9f459944aa48d0ec169c427c2d6
Autor:
Sung-Tau Chou, Hsuan-Yu Peng, Kuan-Chi Mo, Yuan-Ming Hsu, Guan-Hsun Wu, Jenn-Ren Hsiao, Su-Fang Lin, Horng-Dar Wang, Shine-Gwo Shiah
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Discoidin domain receptor-1 (DDR1) tyrosine kinase is highly expressed in a variety of human cancers and involved in various steps of tumorigenesis. However, the precise mechanisms underlying the abnormal expression of DDR1 in ora
Externí odkaz:
https://doaj.org/article/153c868dcc614b069a17bec55af4cc54
TNF-α-induced miR-450a mediates TMEM182 expression to promote oral squamous cell carcinoma motility.
Autor:
En-Wei Hsing, Shine-Gwo Shiah, Hsuan-Yu Peng, Ya-Wen Chen, Chih-Pin Chuu, Jenn-Ren Hsiao, Ping-Chiang Lyu, Jang-Yang Chang
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213463 (2019)
Distant metastasis leads oral cancer patients into a poor survival rate and a high recurrence stage. During tumor progression, dysregulated microRNAs (miRNAs) have been reported to involve tumor initiation and modulate oral cancer malignancy. MiR-450
Externí odkaz:
https://doaj.org/article/b6c5a32b3d324078876fe5fbd106b214
Autor:
Shine-Gwo Shiah, Michael Hsiao, Yi-Shing Shieh, Jang-Yang Chang, Chi-Long Chen, Jenn-Ren Hsiao, Li-Hsing Chi, Yuan-Ming Hsu, Guan-Hsun Wu, Tsung-Ching Lai, Yu-Chan Chang, Hsuan-Yu Peng, Chia-Yi Su, Yuan-Feng Lin, Wei-Min Chang
Supplementary Table 1. Antibodies and Primer list Supplementary Table 2. IPA results for HNSCC upstream transcriptional regulators Supplementary Table 3. Clinical characteristics of RUNX2 in validation HNSCC cohort Supplementary Table 4. Lung colony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31114f34f0d32321f8511610c9e20826
https://doi.org/10.1158/0008-5472.22413744.v1
https://doi.org/10.1158/0008-5472.22413744.v1
Autor:
Shine-Gwo Shiah, Michael Hsiao, Yi-Shing Shieh, Jang-Yang Chang, Chi-Long Chen, Jenn-Ren Hsiao, Li-Hsing Chi, Yuan-Ming Hsu, Guan-Hsun Wu, Tsung-Ching Lai, Yu-Chan Chang, Hsuan-Yu Peng, Chia-Yi Su, Yuan-Feng Lin, Wei-Min Chang
Epigenetic correlates of the head and neck cancer may illuminate its pathogenic roots. Through a gene set enrichment analysis, we found that the oncogenic transcription factor RUNX2 is widely upregulated in the head and neck squamous cell carcinoma (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9076b8cad76aefa7b19a5cfe76bfff4
https://doi.org/10.1158/0008-5472.c.6508803.v1
https://doi.org/10.1158/0008-5472.c.6508803.v1
Autor:
Shine-Gwo Shiah, Michael Hsiao, Yi-Shing Shieh, Jang-Yang Chang, Chi-Long Chen, Jenn-Ren Hsiao, Li-Hsing Chi, Yuan-Ming Hsu, Guan-Hsun Wu, Tsung-Ching Lai, Yu-Chan Chang, Hsuan-Yu Peng, Chia-Yi Su, Yuan-Feng Lin, Wei-Min Chang
Supplementary Figure 1. RUNX2 is nucleus location protein among HNSCC cells. Supplementary Figure 2. RUNX2 was a poor prognostic marker in HNSCC. Supplementary Figure 3. Lung colony formation ability of HNSCC cells. Supplementary Figure 4. RUNX2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013b58691f4f2d07cd893668bd7c13fc
https://doi.org/10.1158/0008-5472.22413747
https://doi.org/10.1158/0008-5472.22413747
Autor:
Hsuan-Yu Peng, Yun-Ching Cheng, Yuan-Ming Hsu, Guan-Hsun Wu, Ching-Chuan Kuo, Jing-Ping Liou, Jang-Yang Chang, Shiow-Lian Catherine Jin, Shine-Gwo Shiah
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158440 (2016)
Microtubule inhibitors have been shown to inhibit Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signal transduction pathway in various cancer cells. However, little is known of the mechanism by which the microtubule i
Externí odkaz:
https://doaj.org/article/ad73fcf91c054cb490d13e16a9687a2c
Autor:
Yuan Ming Hsu, Sung Tau Chou, Jenn Ren Hsiao, Shine Gwo Shiah, Yi Shing Shieh, Hsuan Yu Peng, Guan Hsun Wu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 11, Pp 554-565 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Highlights • Down-regulation of CISH in OSCC tissues and cell lines. • CISH mediates cellular functions through STAT3 inhibition. • MiR-944 regulates cellular functions through direct binding of CISH. • Cigarette smoking-mediated miR-944/CISH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad6b35f71ccd8ad2e44f941f8154f14
http://www.sciencedirect.com/science/article/pii/S1476558620301433
http://www.sciencedirect.com/science/article/pii/S1476558620301433