Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Hsuan-Cheng Huang"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Interstitial lung disease (ILD) is the primary cause of mortality in systemic sclerosis (SSc), an autoimmune disease characterized by tissue fibrosis. SSc-related ILD (SSc-ILD) occurs more frequently in females aged 30–55 years,
Externí odkaz:
https://doaj.org/article/5f193c0c75cf4678a85082159fae9ecc
Autor:
Yih-Yun Sun, Chiao-Yu Hsieh, Jian-Hung Wen, Tzu-Yang Tseng, Jia-Hsin Huang, Yen-Jen Oyang, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117070- (2024)
Predicting drug responses based on individual transcriptomic profiles holds promise for refining prognosis and advancing precision medicine. Although many studies have endeavored to predict the responses of known drugs to novel transcriptomic profile
Externí odkaz:
https://doaj.org/article/1ac26b9e1ba64bd5a69f2e32291be79d
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background The nuclear factor kappa B (NFκB) regulatory pathways downstream of tumor necrosis factor (TNF) play a critical role in carcinogenesis. However, the widespread influence of NFκB in cells can result in off-target effects, making
Externí odkaz:
https://doaj.org/article/1132023f887049e18462a48ec3f52d51
Autor:
Yi-Chun Kao, Yi-Wen Chang, Charles P. Lai, Nai-Wen Chang, Chen-Hao Huang, Chien-Sheng Chen, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstarct Ectopic ATP synthase on the plasma membrane (eATP synthase) has been found in various cancer types and is a potential target for cancer therapy. However, whether it provides a functional role in tumor progression remains unclear. Here, quant
Externí odkaz:
https://doaj.org/article/935dc631597d4e1bb53634e0a697807d
Autor:
Yi-Wen Chang, T. Tony Yang, Min-Chun Chen, Y-geh Liaw, Chieh-Fan Yin, Xiu-Qi Lin-Yan, Ting-Yu Huang, Jen-Tzu Hou, Yi-Hsuan Hung, Chia-Lang Hsu, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Ectopic ATP synthase complex (eATP synthase), located on cancer cell surface, has been reported to possess catalytic activity that facilitates the generation of ATP in the extracellular environment to establish a suitable microenvironment an
Externí odkaz:
https://doaj.org/article/722270eaa3034aba9f1695a66af0cee9
Autor:
Chiao-Hui Hsieh, Chen-Tsung Huang, Yi-Sheng Cheng, Chun-Hua Hsu, Wen-Ming Hsu, Yun-Hsien Chung, Yen-Lin Liu, Tsai-Shan Yang, Chia-Yu Chien, Yu-Hsuan Lee, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115429- (2023)
Neuroblastoma, a childhood cancer affecting the sympathetic nervous system, continues to challenge the development of potent treatments due to the limited availability of druggable targets for this aggressive illness. Recent investigations have uncov
Externí odkaz:
https://doaj.org/article/4b40b94a1f034bc0b617bd5fa477fa59
Autor:
Chiao-Yu Hsieh, Jian-Hung Wen, Shih-Ming Lin, Tzu-Yang Tseng, Jia-Hsin Huang, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 150-157 (2023)
Single-cell RNA sequencing (scRNA-seq) technology allows massively parallel characterization of thousands of cells at the transcriptome level. scRNA-seq is emerging as an important tool to investigate the cellular components and their interactions in
Externí odkaz:
https://doaj.org/article/f9238b3f09bd48209dd6cc3371a95b8e
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 185-201 (2023)
Circular permutation (CP) is a protein sequence rearrangement in which the amino- and carboxyl-termini of a protein can be created in different positions along the imaginary circularized sequence. Circularly permutated proteins usually exhibit conser
Externí odkaz:
https://doaj.org/article/c0ca2f20e5fe484a895ae68dc4d90a71
Autor:
Chia-Lang Hsu, Chieh-Fan Yin, Yi-Wen Chang, Ya-Chih Fan, Shih-Han Lin, Yu-Ching Wu, Hsuan-Cheng Huang, Hsueh-Fen Juan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-10 (2022)
Abstract The small nucleolar RNA host gene 1 (SNHG1) is a novel oncogenic long non-coding RNA (lncRNA) aberrantly expressed in different tumor types. We previously found highly expressed SNHG1 was associated with poor prognosis and MYCN status in neu
Externí odkaz:
https://doaj.org/article/c47c26a408c14356b4e2e7bbad30aa47
Autor:
Wen-Hsuan Yu, Chia-Lang Hsu, Chen-Ching Lin, Yen-Jen Oyang, Hsueh-Fen Juan, Hsuan-Cheng Huang
Publikováno v:
BMC Medical Genomics, Vol 14, Iss S3, Pp 1-12 (2022)
Abstract Background Recently, non-coding RNAs are of growing interest, and more scientists attach importance to research on their functions. Long non-coding RNAs (lncRNAs) are defined as non-protein coding transcripts longer than 200 nucleotides. We
Externí odkaz:
https://doaj.org/article/237fff6bc81242afba8cca2ad1fd089f