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SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.

Autor: Lu Q; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA; The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA., Liu J; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA; The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA., Zhao S; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Gomez Castro MF; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Laurent-Rolle M; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA., Dong J; Ab Studio, Inc., Hayward, CA 94545, USA., Ran X; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Damani-Yokota P; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Tang H; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Karakousi T; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA; The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA., Son J; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Kaczmarek ME; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Zhang Z; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA; The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA., Yeung ST; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., McCune BT; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Chen RE; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Tang F; BIOPIC, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing 100871, China., Ren X; BIOPIC, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing 100871, China., Chen X; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Hsu JCC; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA., Teplova M; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA; The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA., Huang B; Ab Studio, Inc., Hayward, CA 94545, USA., Deng H; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Long Z; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Mudianto T; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Jin S; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Lin P; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Du J; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Zang R; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Su TT; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA., Herrera A; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Zhou M; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Yan R; Joint Research Center of Hangzhou First Hospital Group and Westlake University, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Cui J; Kactus Biosystems Co., Ltd., Shanghai 201114, China., Zhu J; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Zhou Q; Joint Research Center of Hangzhou First Hospital Group and Westlake University, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China., Wang T; Quantitative Biomedical Research Center, Department of Population and Data Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Ma J; Department of Computer Science, Purdue University, West Lafayette, IN 47907, USA., Koralov SB; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Zhang Z; BIOPIC, Beijing Advanced Innovation Center for Genomics, School of Life Sciences, Peking University, Beijing 100871, China., Aifantis I; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Segal LN; Division of Pulmonary and Critical Care Medicine, New York University School of Medicine, New York, NY 10016, USA., Diamond MS; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA., Khanna KM; The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Stapleford KA; Department of Microbiology, New York University Grossman School of Medicine, New York, NY 10016, USA., Cresswell P; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519, USA., Liu Y; Ab Studio, Inc., Hayward, CA 94545, USA., Ding S; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: siyuan.ding@wustl.edu., Xie Q; Westlake Laboratory of Life Sciences and Biomedicine, Center for Infectious Diseases Research, Zhejiang Provincial Laboratory of Life Sciences and Biomedicine, Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China; Institute of Basics Medical Sciences, Westlake Institute for Advanced Study, School of Life Sciences, Westlake University, Hangzhou, Zhejiang Province 310024, China. Electronic address: xieqi@westlake.edu.cn., Wang J; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA; The Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA. Electronic address: jun.wang@nyulangone.org.

Publikováno v: Immunity [Immunity] 2021 Jun 08; Vol. 54 (6), pp. 1304-1319.e9. Date of Electronic Publication: 2021 May 09.

Precision spherical nucleic acids for delivery of anticancer drugs.

Autor: Bousmail D; Department of Chemistry , Centre for Self-Assembled Chemical Structures (CSACS) , McGill University , 801 Sherbrooke St. W. , Montreal , Canada . Email: hanadi.sleiman@mcgill.ca., Amrein L; Department of Oncology , Jewish General Hospital , 3755 Cote Sainte-Catherine Rd. , Montreal , Canada . Email: lpanasci@hotmail.com., Fakhoury JJ; Department of Chemistry , Centre for Self-Assembled Chemical Structures (CSACS) , McGill University , 801 Sherbrooke St. W. , Montreal , Canada . Email: hanadi.sleiman@mcgill.ca., Fakih HH; Department of Chemistry , Centre for Self-Assembled Chemical Structures (CSACS) , McGill University , 801 Sherbrooke St. W. , Montreal , Canada . Email: hanadi.sleiman@mcgill.ca., Hsu JCC; Department of Chemistry , Centre for Self-Assembled Chemical Structures (CSACS) , McGill University , 801 Sherbrooke St. W. , Montreal , Canada . Email: hanadi.sleiman@mcgill.ca., Panasci L; Department of Oncology , Jewish General Hospital , 3755 Cote Sainte-Catherine Rd. , Montreal , Canada . Email: lpanasci@hotmail.com., Sleiman HF; Department of Chemistry , Centre for Self-Assembled Chemical Structures (CSACS) , McGill University , 801 Sherbrooke St. W. , Montreal , Canada . Email: hanadi.sleiman@mcgill.ca.

Publikováno v: Chemical science [Chem Sci] 2017 Sep 01; Vol. 8 (9), pp. 6218-6229. Date of Electronic Publication: 2017 Jul 05.