Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Hsu Hsin Chen"'
Autor:
Bing Wu, Hayley M. Bennett, Xin Ye, Akshayalakshmi Sridhar, Celine Eidenschenk, Christine Everett, Evgeniya V. Nazarova, Hsu-Hsin Chen, Ivana K. Kim, Margaret Deangelis, Leah A. Owen, Cynthia Chen, Julia Lau, Minyi Shi, Jessica M. Lund, Ana Xavier-Magalhães, Neha Patel, Yuxin Liang, Zora Modrusan, Spyros Darmanis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Multiomic profiling of single cells by sequencing is a powerful technique for investigating cellular diversity. Existing droplet-based microfluidic methods produce many cell-free droplets, underutilizing bead barcodes and reagents. Combinato
Externí odkaz:
https://doaj.org/article/8f7c0a3ec95940b8a83501d58f25ab55
Autor:
Luz D. Orozco, Hsu-Hsin Chen, Christian Cox, Kenneth J. Katschke, Jr., Rommel Arceo, Carmina Espiritu, Patrick Caplazi, Sarajane Saturnio Nghiem, Ying-Jiun Chen, Zora Modrusan, Amy Dressen, Leonard D. Goldstein, Christine Clarke, Tushar Bhangale, Brian Yaspan, Marion Jeanne, Michael J. Townsend, Menno van Lookeren Campagne, Jason A. Hackney
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112298- (2023)
Externí odkaz:
https://doaj.org/article/50149307557045f491296fd14962a70c
Autor:
Luz D. Orozco, Hsu-Hsin Chen, Christian Cox, Kenneth J. Katschke, Jr., Rommel Arceo, Carmina Espiritu, Patrick Caplazi, Sarajane Saturnio Nghiem, Ying-Jiun Chen, Zora Modrusan, Amy Dressen, Leonard D. Goldstein, Christine Clarke, Tushar Bhangale, Brian Yaspan, Marion Jeanne, Michael J. Townsend, Menno van Lookeren Campagne, Jason A. Hackney
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1246-1259.e6 (2020)
Summary: Age-related macular degeneration (AMD) is a leading cause of vision loss. To better understand disease pathogenesis and identify causal genes in GWAS loci for AMD risk, we present a comprehensive database of human retina and retinal pigment
Externí odkaz:
https://doaj.org/article/1d550e817e174a2695fd2849cb2c4767
Autor:
Chao-Yu, Liu, Hsu-Hsin, Chen
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2560
Transcriptome profiling at single-cell resolution allows us to identify and assess functional cell types and cellular states, including those within degenerating ocular tissues in retinitis pigmentosa. The technology is particularly valuable when stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da41a7bbd8043729019d252fab69df84
https://pubmed.ncbi.nlm.nih.gov/36481908
https://pubmed.ncbi.nlm.nih.gov/36481908
Autor:
Chao-Yu Liu, Hsu-Hsin Chen
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626504
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d54be96f83cbe85e51bf0ced83a8868f
https://doi.org/10.1007/978-1-0716-2651-1_30
https://doi.org/10.1007/978-1-0716-2651-1_30
Autor:
Luz D. Orozco, Leah Owen, Jeffrey Hofmann, Amy D. Stockwell, Jianhua Tao, Susan Haller, Vineeth T. Mukundan, Christine Clarke, Jessica Lund, Akshayalakshmi Sridhar, Julie L. Barr, Rylee A. Zavala, Elijah C. Graves, Charles Zhang, Nadine Husami, Robert Finley, Elizabeth Au, John H. Lillvis, Michael H. Farkas, Akbar Shakoor, Richard M. Sherva, Ivana K. Kim, Joshua S. Kaminker, Michael J. Townsend, Lindsay A. Farrer, Brian L. Yaspan, Hsu-Hsin Chen, Margaret M. DeAngelis
Age-related Macular Degeneration (AMD) is a leading cause of blindness, affecting 200 million people worldwide. We present a comprehensive molecular atlas for different stages of AMD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07fcd58dd2422fa1d90174ae6aa8727
Autor:
Hsu-Hsin Chen, Maaike Welling, Donald B. Bloch, Javier Muñoz, Edwin Mientjes, Xinjie Chen, Cody Tramp, Jie Wu, Akiko Yabuuchi, Yu-Fen Chou, Christa Buecker, Adrian Krainer, Rob Willemsen, Albert J. Heck, Niels Geijsen
Publikováno v:
Stem Cell Reports, Vol 3, Iss 5, Pp 892-904 (2014)
The scarcity of primordial germ cells (PGCs) in the developing mammalian embryo hampers robust biochemical analysis of the processes that underlie early germ cell formation. Here, we demonstrate that DAZL, a germ cell-specific RNA binding protein, is
Externí odkaz:
https://doaj.org/article/25751e2151664c4a85e351f61e3f039b
Autor:
Luz D. Orozco, Leah A. Owen, Jeffrey Hofmann, Amy D. Stockwell, Jianhua Tao, Susan Haller, Vineeth T. Mukundan, Christine Clarke, Jessica Lund, Akshayalakshmi Sridhar, Oleg Mayba, Julie L. Barr, Rylee A. Zavala, Elijah C. Graves, Charles Zhang, Nadine Husami, Robert Finley, Elizabeth Au, John H. Lillvis, Michael H. Farkas, Akbar Shakoor, Richard Sherva, Ivana K. Kim, Joshua S. Kaminker, Michael J. Townsend, Lindsay A. Farrer, Brian L. Yaspan, Hsu-Hsin Chen, Margaret M. DeAngelis
Publikováno v:
Cell Genomics. :100302
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5019f5766a9bcf8ae4ba1059a766b93
https://doi.org/10.1016/j.xgen.2023.100302
https://doi.org/10.1016/j.xgen.2023.100302
Autor:
Anneke I. den Hollander, Robert F. Mullins, Luz D. Orozco, Andrew P. Voigt, Hsu-Hsin Chen, Tobias Strunz, Felix Grassmann, Jonathan L. Haines, Jonas J.W. Kuiper, Santa J. Tumminia, Rando Allikmets, Gregory S. Hageman, Dwight Stambolian, Caroline C.W. Klaver, Jef D. Boeke, Hao Chen, Lee Honigberg, Suresh Katti, Kelly A. Frazer, Bernhard H.F. Weber, Michael B. Gorin
Publikováno v:
Experimental Eye Research, 225
Experimental Eye Research, 225:109248. Academic Press
Experimental Eye Research, 225:109248. Academic Press
Genomic studies in age-related macular degeneration (AMD) have identified genetic variants that account for the majority of AMD risk. An important next step is to understand the functional consequences and downstream effects of the identified AMD-ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d947d06bcb1649a9c0ededef4e755a54
https://doi.org/10.1016/j.exer.2022.109248
https://doi.org/10.1016/j.exer.2022.109248
Autor:
Libo Wang, Margery A. Connelly, Anne G. Ostermeyer, Hsu-hsin Chen, David L. Williams, Deborah A. Brown
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 4, Pp 807-815 (2003)
Free cholesterol (FC) has been reported to efflux from cells through caveolae, which are 50–100 nm plasma membrane pits. The 22 kDa protein caveolin-1 is concentrated in caveolae and is required for their formation. The HDL scavenger receptor BI (S
Externí odkaz:
https://doaj.org/article/60ead82cd5d447d88c58fef88d7a8c4f