Zobrazeno 1 - 10
of 621
pro vyhledávání: '"HspB1"'
Publikováno v:
Open Life Sciences, Vol 19, Iss 1, Pp 639-52 (2024)
The mortality rate of acute-on-chronic liver failure (ACLF) remains significantly elevated; hence, this study aimed to investigate the impact of heat shock protein family B (small) member 1 (HSPB1) on ACLF in vivo and in vitro and the underlying mech
Externí odkaz:
https://doaj.org/article/3592a956615544978593ed662e106c8f
Autor:
Xiaole Meng, Xiao Peng, Wanxin Ouyang, Hui Li, Risi Na, Wenting Zhou, Xuting You, Yuhuan Li, Xin Pu, Ke Zhang, Junjie Xia, Jie Wang, Guohong Zhuang, Huamei Tang, Zhihai Peng
Publikováno v:
Biological Procedures Online, Vol 25, Iss 1, Pp 1-23 (2023)
Abstract Background Musashi-2 (MSI2) is a critical RNA-binding protein (RBP) whose ectopic expression drives the pathogenesis of various cancers. Accumulating evidence suggests that inducing ferroptosis of tumor cells can inhibit their malignant biol
Externí odkaz:
https://doaj.org/article/aa2da4cd9ab64a2baf8d883cbed102f9
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS) are three nervous system diseases that partially overlap clinically and genetically. However, bulk RNA-sequencing did not accurately detect the core p
Externí odkaz:
https://doaj.org/article/c0b88462dead405999d7eb65bb79029c
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-26 (2023)
Abstract Background Glioma exhibit heterogeneous susceptibility for targeted ferroptosis. How circRNAs alterations in glioma promote iron metabolism and ferroptosis defense remains unclarified. Methods The highly enriched circRNAs in glioblastoma (GB
Externí odkaz:
https://doaj.org/article/03c3275a3a0f449c8e0e2cdbd40d8859
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Heat shock protein beta-1 (HSPB1) is a crucial biomarker for pathological processes in various cancers. However, the clinical value and function of HSPB1 in breast cancer has not been extensively explored. Therefore, we adopted a
Externí odkaz:
https://doaj.org/article/2243d4ad82474da2a0a5bbed8e199951
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background FYN is a nonreceptor tyrosine kinase that regulates diverse pathological processes. The pro-cancer role of FYN in multiple malignancies has been elucidated. However, the mechanisms that FYN promotes gastric cancer (GC) progression
Externí odkaz:
https://doaj.org/article/ae9b73fac6164b2186d7a142d62cf1f5
Akademický článek
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Autor:
Wenhan Yang, Kaiping Gao, Youhui Qian, Yongyi Huang, Qin Xiang, Cheng Chen, Qianqian Chen, Yiling Wang, Fuyuan Fang, Qihan He, Siqi Chen, Juan Xiong, Yangchao Chen, Ni Xie, Duo Zheng, Rihong Zhai
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-20 (2022)
Abstract Background Transfer RNA-derived fragments (tRFs) are a new class of small non-coding RNAs. Recent studies suggest that tRFs participate in some pathological processes. However, the biological functions and mechanisms of tRFs in non-small cel
Externí odkaz:
https://doaj.org/article/99052f787ac849929d5bd1ca7b51df9b
Autor:
Mina Nosrati, Neda Shakour, Toktam Sahranavard, Fatemeh Sadabadi, Sara Saffar Soflaei, Hamideh Ghazizadeh, Maryam Mohammadi Bajgiran, Mohamad Reza Latifi, Mohammad Amin Mansouri, Mahmoud Ebrahimi, Mohsen Mouhebati, Seyed Hassan Mirshafee, Masoumeh Haghighi, Reza Assaran Darban, Ensieh Akbarpour, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan
Publikováno v:
Reviews in Clinical Medicine, Vol 9, Iss 1, Pp 28-33 (2022)
Introduction: Diabetes (DM) is a type of metabolic disorder that its types are generated by collectingof genetic and environmental risk agents. Here, the association between HSPB1 polymorphism as a genetic risk factor and DM was investigated. Methods
Externí odkaz:
https://doaj.org/article/7a8cd928bc81476496c39768cc9f0b52
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2737-2742 (2022)
Accumulating studies have demonstrated that hyperbaric oxygen (HBO) treatment alleviates spinal cord injury (SCI). However, the underlying mechanism by which HBO alleviates SCI remains to be elucidated. In this study, we performed genome-wide transcr
Externí odkaz:
https://doaj.org/article/50f77794678a413e9ec45cafd64dba0a