Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hsiuyi Tseng"'
Autor:
Levi A. Garraway, Gad Getz, Meenhard Herlyn, Reinhard Dummer, Todd R. Golub, Matthew Meyerson, Roman K. Thomas, William R. Sellers, Glenn Dranoff, F. Stephen Hodi, Casey Gates, Hsiuyi Tseng, Heidi Greulich, Elisabeth Laine, Jennifer M. Marmion, Whei Feng, Wendy Winckler, Rameen Beroukhim, Alissa C. Baker, William M. Lin
The classification of human tumors based on molecular criteria offers tremendous clinical potential; however, discerning critical and “druggable” effectors on a large scale will also require robust experimental models reflective of tumor genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116fa90cddfa9dcfe67f41cce7326a9a
https://doi.org/10.1158/0008-5472.c.6497147.v1
https://doi.org/10.1158/0008-5472.c.6497147.v1
Supplementary Information from Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma
Autor:
Levi A. Garraway, Gad Getz, Meenhard Herlyn, Reinhard Dummer, Todd R. Golub, Matthew Meyerson, Roman K. Thomas, William R. Sellers, Glenn Dranoff, F. Stephen Hodi, Casey Gates, Hsiuyi Tseng, Heidi Greulich, Elisabeth Laine, Jennifer M. Marmion, Whei Feng, Wendy Winckler, Rameen Beroukhim, Alissa C. Baker, William M. Lin
Supplementary Information from Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f7aa981e17f5ada0bcdb0a25354968
https://doi.org/10.1158/0008-5472.22373603
https://doi.org/10.1158/0008-5472.22373603
Autor:
Lian Xu, Sigitas Verselis, Hsiuyi Tseng, Robert Manning, Leukothea Ioakimidis, Steven P. Treon, C. A. Hanzis, Zachary R. Hunter, Barry Turnbull, Patricia Sheehy, Christopher J. Patterson, Guang Yang, Edward A. Fox
Publikováno v:
British Journal of Haematology. 154:223-228
The incorporation of rituximab into various regimens has improved depth of response in Waldenstrom macroglobulinaemia (WM), though the impact of achieving better responses remains to be determined. We examined response depth on progression-free survi
Autor:
Casey Gates, William M. Lin, Whei Feng, Levi A. Garraway, Matthew Meyerson, Todd R. Golub, Jennifer M. Marmion, F. Stephen Hodi, Meenhard Herlyn, William R. Sellers, Rameen Beroukhim, Gad Getz, Roman K. Thomas, Heidi Greulich, Wendy Winckler, Glenn Dranoff, Alissa C. Baker, Reinhard Dummer, Elisabeth Laine, Hsiuyi Tseng
Publikováno v:
Cancer research
The classification of human tumors based on molecular criteria offers tremendous clinical potential; however, discerning critical and “druggable” effectors on a large scale will also require robust experimental models reflective of tumor genomic
Autor:
Hsiuyi Tseng, Yangsheng Zhou, Christopher J. Patterson, Bangmin Zhu, Jenny Sun, Lian Xu, Kaveh Maghsoudi, Nikhil C. Munshi, Guang Yang, Xia Liu, Bryan Ciccarelli, Mariateresa Fulciniti, Steven P. Treon, Zachary R. Hunter, Ping Gong
Publikováno v:
Leukemialymphoma. 52(9)
Histone deacetylases (HDACs) are aberrantly expressed, and inhibitors of HDACs induce apoptosis in lymphoplasmacytic cells (LPCs) in Waldenstrom macroglobulinemia (WM). The molecular profile by which these agents induce apoptosis in WM LPCs remains t
Autor:
Steven P, Treon, Guang, Yang, Christine, Hanzis, Leukothea, Ioakimidis, Sigitas J, Verselis, Edward A, Fox, Lian, Xu, Zachary R, Hunter, Hsiuyi, Tseng, Robert J, Manning, Christopher J, Patterson, Patricia, Sheehy, Barry, Turnbull
Publikováno v:
British journal of haematology. 154(2)
The incorporation of rituximab into various regimens has improved depth of response in Waldenstrom macroglobulinaemia (WM), though the impact of achieving better responses remains to be determined. We examined response depth on progression-free survi
Autor:
Bryan Ciccarelli, Hsiuyi Tseng, Yang Cao, Leukothea Ioakimidis, Steven P. Treon, Christopher J. Patterson, Jenny Sun, Xia Liu, Zachary R. Hunter, Patricia Sheehy, Yangsheng Zhou, Scott J. Rodig, Lian Xu, Robert Manning, Guang Yang, Christina Hanzis
Publikováno v:
Clinical lymphoma, myelomaleukemia. 11(1)
Waldenstrom's macroglobulinemia (WM) patients often present with anemia as their primary disease manifestation that may be related to hepcidin, an important regulator of iron homeostasis. We therefore determined hepcidin levels in 53 WM patients, and
Autor:
Christopher J. Patterson, Guang Yang, Xia Liu, Bryan Ciccarelli, Leukothea Ioakimidis, Steven P. Treon, Yangsheng Zhou, Ping Gong, Jenny Sun, Lian Xu, Robert Manning, Hsiuyi Tseng, Evdoxia Hatjiharissi
Publikováno v:
Clinical lymphomamyeloma. 9(1)
Backgound: The assessment of disease burden is often difficult in patients with Waldenstrom’s macroglobulinemia (WM) who receive rituximab due to the induction of an IgM flare, and following the removal of serum IgM by plasmapheresis. Soluble CD27
Autor:
Rosalia Rabinovsky, Lucia E. Rameh, Jesse S. Boehm, Piyush Gupta, Peter Sandy, Anna C. Schinzel, David A. Barbie, Tyler Jacks, Krishna Murthi Vasudevan, Bhaskar Dutta, Gordon B. Mills, Jessica J. Kim, Aysegul A. Sahin, Bryan T. Hennessy, Panisa Pochanard, Levi A. Garraway, Michael A. Davies, David E. Root, Ana M. Gonzalez-Angulo, Katherine Stemke-Hale, Yiling Lu, Hsiuyi Tseng, Serena J. Silver, Eric S. Lander, So Young Kim, Ana Lluch, Corwin Joy, William R. Sellers, William C. Hahn, Jan H. Reiling, Chontelle J. McNear, Ian F. Dunn, Qing Sheng, Sebastian Hoersch
Publikováno v:
Cancer cell. 16(1)
SummaryDysregulation of the phosphatidylinositol 3-kinase (PI3K) signaling pathway occurs frequently in human cancer. PTEN tumor suppressor or PIK3CA oncogene mutations both direct PI3K-dependent tumorigenesis largely through activation of the AKT/PK
Autor:
Jingrui Jiang, Steven P. Treon, Yangsheng Zhou, Megan Lewicki, Robert Manning, Hsiuyi Tseng, Guang Yang, Christopher J. Patterson, Yang Cao, Jenny Sun, Christina Hanzis, Zachary R. Hunter, Xia Liu, Lian Xu, Philip Brodsky
Publikováno v:
Blood. 116:1912-1912
Abstract 1912 Background: Waldenstrom's Macroglobulinemia (WM) is a rare low grade non-Hodgkin's lymphoma characterized by the accumulation of IgM secreting lymphoplasmacytic cells in (LPC) the bone marrow, an elevated serum IgM, and frequently accom