Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Hsiung-Lin Tu"'
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109486- (2024)
Summary: Nuclear factor kappa B (NF-κB) is a key regulator in immune signaling and is known to exhibit a digital activation pattern. Yet the molecular basis underlying the heterogeneity in NF-κB activation at single-cell level is not entirely under
Externí odkaz:
https://doaj.org/article/f4788d32d9334588a647fbd05626f697
Publikováno v:
Advanced Science, Vol 10, Iss 31, Pp n/a-n/a (2023)
Abstract In this study, the potential of complex emulsions is investigated as transducers in sensing applications. Complex emulsions are stabilized without external detergents by developing a novel α‐cyanostilbene substituted with PEG and semi‐p
Externí odkaz:
https://doaj.org/article/064a8512ea6845699f9689756de891d5
Autor:
Sofani Tafesse Gebreyesus, Asad Ali Siyal, Reta Birhanu Kitata, Eric Sheng-Wen Chen, Bayarmaa Enkhbayar, Takashi Angata, Kuo-I Lin, Yu-Ju Chen, Hsiung-Lin Tu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Single-cell proteomics is an emerging approach to characterize cell-to-cell differences. Here, the authors develop chips that enable complete proteomic sample processing down to the single-cell level and integrate them with DIA-MS into a streamlined
Externí odkaz:
https://doaj.org/article/c870dbda5f3d411cb7ec0f7263b78694
Autor:
Da-Wei Lin, Yang Liu, Yue-Qi Lee, Po-Jiun Yang, Chia-Tse Ho, Jui-Chung Hong, Jye-Chian Hsiao, Der-Chien Liao, An-Jou Liang, Tzu-Chiao Hung, Yu-Chuan Chen, Hsiung-Lin Tu, Chao-Ping Hsu, Hsiao-Chun Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Establishing protein gradients for asymmetric cell division is fundamental across all kingdoms of life. Here the authors construct asymmetric cell division in E. coli by localizing the expression of RNA polymerase using an orthogonal unipolar scaffol
Externí odkaz:
https://doaj.org/article/20f384df5ff3448aad9923a8582fa11c
Autor:
Jing Lin, Christian Jordi, Minjun Son, Hoang Van Phan, Nir Drayman, Mustafa Fatih Abasiyanik, Luke Vistain, Hsiung-Lin Tu, Savaş Tay
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Digital proximity ligation assay (dPLA) can measure proteins and mRNAs in single cells, but is not compatible with cell imaging and cannot quantify rare proteins due to a high dilution factor. Here the authors present an automated microfluidic device
Externí odkaz:
https://doaj.org/article/1a00989204844592904106524e044438
Autor:
Hsiung-Lin Tu, 涂熊林
93
Mesostructured nanocomposite with complete pore-filling of fluorescent molucules is an interesting subject since such hybrid materials would provide greater control over the molecular alignment and stability. In this thesis, we tried to prepa
Mesostructured nanocomposite with complete pore-filling of fluorescent molucules is an interesting subject since such hybrid materials would provide greater control over the molecular alignment and stability. In this thesis, we tried to prepa
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/54050168477815850040
Autor:
Sofani Tafesse Gebreyesus, Gul Muneer, Chih-Cheng Huang, Asad Ali Siyal, Mihir Anand, Yu-Ju Chen, Hsiung-Lin Tu
Publikováno v:
Lab on a Chip. 23:1726-1751
This article covers exciting developments of recent microfluidics-based single-cell proteomics methods and their utilizations to tackle important biological questions for both basic and translational research.
Publikováno v:
ACS Sensors.
Publikováno v:
Biomicrofluidics
Interactions of the cell with its environment are mediated by the cell membrane and membrane-localized molecules. Supported lipid bilayers have enabled the recapitulation of the basic properties of cell membranes and have been broadly used to further
Publikováno v:
Lab on a Chip. 22:2540-2548
Spatially organized molecular interactions are fundamental features underlying many biochemical processes in cells. These spatially defined reactions are essential to ensure high signaling specificity and are indispensable for maintaining cell functi