Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Hsiu-Ming SHIH"'
Autor:
Hsieh-Tsung Shen, Chin-Sheng Hung, Clilia Davis, Chih-Ming Su, Li-Min Liao, Hsiu-Ming Shih, Kuan-Der Lee, Muhamad Ansar, Ruo-Kai Lin
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 571 (2024)
Breast cancer is a leading cause of cancer mortality in women worldwide. Using the Infinium MethylationEPIC BeadChip, we analyzed plasma sample methylation to identify the SRCIN1 gene in breast cancer patients. We assessed SRCIN1-related roles and pa
Externí odkaz:
https://doaj.org/article/0673084bb3234102bbb1eac3a4244be8
Autor:
Tsan-Tzu Yang, Ming-Feng Chiang, Che-Chang Chang, Shii-Yi Yang, Shih-Wen Huang, Nan-Shih Liao, Hsiu-Ming Shih, Wei Hsu, Kuo-I Lin
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The molecular mechanisms contributing to the regulation of Th17-mediated inflammation remain underexplored. We here report a SUMO-specific protease (SENP)2-mediated pathway induced in pathogenic Th17 cells that restricts the pathogenesis of
Externí odkaz:
https://doaj.org/article/70266b1582b0403d8359af9113548e48
Autor:
Hsuan-Yin Ma, Chun-Yi Lu, Kuo-Chien Tsao, Hsiu-Ming Shih, Ai-Ling Cheng, Li-Min Huang, Luan-Yin Chang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 51, Iss 5, Pp 608-613 (2018)
Objectives: Enterovirus 71 (EV71) may cause neurological and fatal cases. EV71 3C plays an important role on viral replication and possess proteolysis activity. To delineate pathogenesis of EV71 virulence, we studied EV71 3C genetics, protease activi
Externí odkaz:
https://doaj.org/article/6f8cc7a631cb46e1a73f0f99145d5386
Autor:
Yung-Lin Hsieh, Fang-Yi Su, Li-Kai Tsai, Chien-Chang Huang, Yi-Ling Ko, Li-Wen Su, Kai-Yun Chen, Hsiu-Ming Shih, Chun-Mei Hu, Wen-Hwa Lee
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2134-2143.e7 (2019)
Summary: Amyotrophic lateral sclerosis (ALS), the most common motor neuron disease, usually occurs in middle-aged people. However, the molecular basis of age-related cumulative stress in ALS pathogenesis remains elusive. Here, we found that mice defi
Externí odkaz:
https://doaj.org/article/22eb0f2bbc8d4995b37c7c23f0680a3f
Autor:
Ching‐Yu Lin, Shun‐Tai Yang, Shing‐Chuan Shen, Yi‐Chen Hsieh, Fei‐Ting Hsu, Cheng‐Yu Chen, Yung‐Hsiao Chiang, Jian‐Ying Chuang, Kai‐Yun Chen, Tsung‐I Hsu, Wan‐Chong Leong, Yu‐Kai Su, Wei‐Lun Lo, Yi‐Shian Yeh, Yudha Nur Patria, Hsiu‐Ming Shih, Che‐Chang Chang, Szu‐Yi Chou
Publikováno v:
Molecular Oncology, Vol 12, Iss 5, Pp 756-771 (2018)
Glioblastoma multiforme (GBM) is a highly malignant type of brain tumor found in humans. GBM cells reproduce quickly, and the median survival time for patients after therapy is approximately 1 year with a high relapse rate. Current therapies and diag
Externí odkaz:
https://doaj.org/article/bc535ccfd9814d4ca341a341e8391a1e
Autor:
Yu-Ping Chiang, Wang-Huei Sheng, Pei-Lan Shao, Ya-Hui Chi, Yi-Ming Arthur Chen, Szu-Wei Huang, Hsiu-Ming Shih, Luan-Yin Chang, Chun-Yi Lu, Shan-Chwen Chang, Chien-Ching Hung, Li-Min Huang
Publikováno v:
EBioMedicine, Vol 1, Iss 2, Pp 126-132 (2014)
Individual differences in susceptibility to human immunodeficiency virus type 1 (HIV-1) infection have been of interest for decades. We aimed to determine the contribution of large isoform of Mammalian DnaJ (MRJ-L), a HIV-1 Vpr-interacting cellular p
Externí odkaz:
https://doaj.org/article/0900fece302e4518bcb74d64bccaac1d
Autor:
Yik-Khuan Ho, Huijun Zhi, Tara Bowlin, Batsukh Dorjbal, Subha Philip, Muhammad Atif Zahoor, Hsiu-Ming Shih, Oliver John Semmes, Brian Schaefer, J N Mark Glover, Chou-Zen Giam
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005102 (2015)
Human T lymphotropic virus type 1 (HTLV-1) trans-activator/oncoprotein, Tax, impacts a multitude of cellular processes, including I-κB kinase (IKK)/NF-κB signaling, DNA damage repair, and mitosis. These activities of Tax have been implicated in the
Externí odkaz:
https://doaj.org/article/7c698414eeb1451a976c7c249cd70b63
Autor:
Kai-Yun Chen, Chung-Che Wu, Cheng-Fu Chang, Yuan-Hao Chen, Wen-Ta Chiu, Ya-Hsin Lou, Yen-Hua Chen, Hsiu-Ming Shih, Yung-Hsiao Chiang
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Etk/Bmx (epithelial and endothelial tyrosine kinase, also known as BMX), a member of the Tec (tyrosine kinase expressed in hepatocellular carcinoma) family of protein-tyrosine kinases, is an important regulator of signal transduction for the activati
Externí odkaz:
https://doaj.org/article/4513f5bfdaad42be91d6f97e0e6bf8ea
Autor:
John Chung-Che Wu, Kai-Yun Chen, Yu-Wen Yu, Song-Wei Huang, Hsiu-Ming Shih, Wen-Ta Chiu, Yung-Hsiao Chiang, Chia-Yang Shiau
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39226 (2012)
BackgroundMuch recent research effort in traumatic brain injury (TBI) has been devoted to the discovery of a reliable biomarker correlating with severity of injury. Currently, no consensus has been reached regarding a representative marker for trauma
Externí odkaz:
https://doaj.org/article/9cfe0a01ea4a48318b21378619c8350a
Publikováno v:
PLoS Pathogens, Vol 7, Iss 4, p e1002025 (2011)
Activation of I-κB kinases (IKKs) and NF-κB by the human T lymphotropic virus type 1 (HTLV-1) trans-activator/oncoprotein, Tax, is thought to promote cell proliferation and transformation. Paradoxically, expression of Tax in most cells leads to dra
Externí odkaz:
https://doaj.org/article/5901072cfa5e45d69dff8ea53ca48eda