Zobrazeno 1 - 10
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pro vyhledávání: '"Hsiu-Ho Chen"'
Autor:
Chih-Shone Lee, Hsiu-Ho Chen
Publikováno v:
Journal of the Chinese Chemical Society. 41:187-190
Enantiomers of β-lactams bearing aryl, furyl or styryl substituents in the 4-position were chromatographically separated by means of high-performance liquid chromatography on chiral column packed with amino acid-derived chiral stationary phase. Sepa
Publikováno v:
Steroids. 58:414-422
Several 7α-thiosubstituted derivatives of androstenedione have demonstrated effective inhibition of aromatase, the cytochrome P450 enzyme complex responsible for the biosynthesis of estrogens. Introduction of an additional double bond in the A ring
Autor:
Hsiu-Ho Chen, Chih-Shone Lee
Publikováno v:
Journal of the Chinese Chemical Society. 40:169-174
Enantioselective synthesis of optically active β-lactam via ester enolate-imine condensation using homochiral ester 16 and imine 17 provided β-lactam 18a in 77% cc. Lactam 18a, carried C(3) functionality on β-lactam nuclei, provided a potential pr
Autor:
Robert W. Brueggemeier, Hsiu-Ho Chen
Publikováno v:
Steroids. 55:123-127
Effective aromatase inhibitors have been developed that contain aryl functionalities at the 7 alpha-position of the steroid nucleus. The exact interactions of 7 alpha-substituted androstenediones with the active site of aromatase is unknown. Fluoresc
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 37(3)
Androstenedione analogs containing 7 alpha-substituents have proven to be potent inhibitors of aromatase both in vitro and in vivo. Several of these agents have exhibited higher affinity for the enzyme complex than the substrate. In order to examine
Publikováno v:
Archiv der Pharmazie. 312:776-780
Es wird die Darstellung einiger kondensierter Perimidin-Derivate und ihre Prufung auf anorektische Wirkung beschrieben. Die wirksamste Substanz 4c zeigte keine ZNS-Wirkung und dies weist darauf hin, das diese Derivate einen anderen anorektischen Wirk
Autor:
Kang‐Chien Liu, Hsiu‐Ho Chen
Publikováno v:
Archiv der Pharmazie. 318:468-470
Autor:
Hsiu-Ho Chen, Kang-Chien Liu
Publikováno v:
Chemischer Informationsdienst. 15
Autor:
Hsiu‐Ho Chen, Kang‐Chien Liu
Publikováno v:
Chemischer Informationsdienst. 16
Autor:
Hsiu-Ho Chen, Kang-Chien Liu
Publikováno v:
Journal of Heterocyclic Chemistry. 22:1363-1364
Refluxing 2-hydrazinoperimidine (1) with excess amount of diethyl oxalate (2a) gave ethyl 1H-1,2,4-triazolo[4,3-a]perimidine-3-carboxylate (4a) in 84% yield. On the other hand, heating 1 with ethyl pyruvate (2b) in glacial acetic acid afforded 3-meth