Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Hsiu Hua Ma"'
Autor:
I-Jung Lee, Yu-Hua Lan, Ping-Yi Wu, Yan-Wei Wu, Yu-Hung Chen, Sheng-Che Tseng, Tzu-Jiun Kuo, Cheng-Pu Sun, Jia-Tsrong Jan, Hsiu-Hua Ma, Chun-Che Liao, Jian-Jong Liang, Hui-Ying Ko, Chih-Shin Chang, Wen-Chun Liu, Yi-An Ko, Yen-Hui Chen, Zong-Lin Sie, Szu-I Tsung, Yi-Ling Lin, I-Hsuan Wang, Mi-Hua Tao
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTNumerous vaccines have been developed to address the current COVID-19 pandemic, but safety, cross-neutralizing efficacy, and long-term protectivity of currently approved vaccines are still important issues. In this study, we developed a subun
Externí odkaz:
https://doaj.org/article/b226ffaca06841fa8ad7defca441cd0e
Autor:
Shiou-Chih Hsu, Kun-Hsien Lin, Yung-Chieh Tseng, Yang-Yu Cheng, Hsiu-Hua Ma, Ying-Chun Chen, Jia-Tsrong Jan, Chung-Yi Wu, Che Ma
Publikováno v:
Vaccines, Vol 12, Iss 6, p 569 (2024)
An incomplete Freund’s adjuvant elicited an overt pathogenesis in vaccinated mice following the intranasal challenge of A/California/07/2009 (H1N1) virus despite the induction of a higher specific antibody titer than other adjuvanted formulations.
Externí odkaz:
https://doaj.org/article/d17f26fc2c5c4ce69acf0dcfc0b1c176
Autor:
I-Jung Lee, Cheng-Pu Sun, Ping-Yi Wu, Yu-Hua Lan, I-Hsuan Wang, Wen-Chun Liu, Joyce Pei-Yi Yuan, Yu-Wei Chang, Sheng-Che Tseng, Szu-I Tsung, Yu-Chi Chou, Monika Kumari, Yin-Shiou Lin, Hui-Feng Chen, Tsung-Yen Chen, Chih-Chao Lin, Chi-Wen Chiu, Chung-Hsuan Hsieh, Cheng-Ying Chuang, Chao-Min Cheng, Hsiu-Ting Lin, Wan-Yu Chen, Fu-Fei Hsu, Ming-Hsiang Hong, Chun-Che Liao, Chih-Shin Chang, Jian-Jong Liang, Hsiu-Hua Ma, Ming-Tsai Chiang, Hsin-Ni Liao, Hui-Ying Ko, Liang-Yu Chen, Yi-An Ko, Pei-Yu Yu, Tzu-Jing Yang, Po-Cheng Chiang, Shang-Te Hsu, Yi-Ling Lin, Chong-Chou Lee, Han-Chung Wu, Mi-Hua Tao
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-13 (2022)
Abstract Background With the continuous emergence of new SARS-CoV-2 variants that feature increased transmission and immune escape, there is an urgent demand for a better vaccine design that will provide broader neutralizing efficacy. Methods We repo
Externí odkaz:
https://doaj.org/article/f52cdfcd615b49699347c79554e26b54
Autor:
Chia-En Lien, Yi-Jiun Lin, Charles Chen, Wei-Cheng Lian, Tsun-Yung Kuo, John D. Campbell, Paula Traquina, Meei-Yun Lin, Luke Tzu-Chi Liu, Ya-Shan Chuang, Hui-Ying Ko, Chun-Che Liao, Yen-Hui Chen, Jia-Tsrong Jan, Hsiu-Hua Ma, Cheng-Pu Sun, Yin-Shiou Lin, Ping-Yi Wu, Yu-Chiuan Wang, Mi-Hua Tao, Yi-Ling Lin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract The COVID-19 pandemic presents an unprecedented challenge to global public health. Rapid development and deployment of safe and effective vaccines are imperative to control the pandemic. In the current study, we applied our adjuvanted stable
Externí odkaz:
https://doaj.org/article/97e4b89a509c4a8585861a8a1abe0884
Autor:
Cheng-Pu Sun, Jia-Tsrong Jan, I-Hsuan Wang, Hsiu-Hua Ma, Hui-Ying Ko, Ping-Yi Wu, Tzu-Jiun Kuo, Hsin-Ni Liao, Yu-Hua Lan, Zong-Lin Sie, Yen-Hui Chen, Yi-An Ko, Chun-Che Liao, Liang-Yu Chen, I-Jung Lee, Szu-I Tsung, Yun-Ju Lai, Ming-Tsai Chiang, Jian-Jong Liang, Wen-Chun Liu, Jing-Rong Wang, Joyce Pei-Yi Yuan, Yin-Shiou Lin, Yi-Ching Tsai, Shie-Liang Hsieh, Chia-Wei Li, Han-Chung Wu, Tai-Ming Ko, Yi-Ling Lin, Mi-Hua Tao
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009758 (2021)
Since the pandemic of COVID-19 has intensely struck human society, small animal model for this infectious disease is in urgent need for basic and pharmaceutical research. Although several COVID-19 animal models have been identified, many of them show
Externí odkaz:
https://doaj.org/article/4c7d04f4f9e34a85ac0d0588129271b2
Autor:
Rakesh Kulkarni, Wen-Ching Chen, Ying Lee, Chi-Fei Kao, Shiu-Lok Hu, Hsiu-Hua Ma, Jia-Tsrong Jan, Chun-Che Liao, Jian-Jong Liang, Hui-Ying Ko, Cheng-Pu Sun, Yin-Shoiou Lin, Yu-Chiuan Wang, Sung-Chan Wei, Yi-Ling Lin, Che Ma, Yu-Chan Chao, Yu-Chi Chou, Wen Chang
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257191 (2021)
COVID-19 in humans is caused by Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that belongs to the beta family of coronaviruses. SARS-CoV-2 causes severe respiratory illness in 10-15% of infected individuals and mortality in 2-3%. Vacci
Externí odkaz:
https://doaj.org/article/6a4e62dbbd994a8fa9659f32ad19f2bf
Autor:
Hsiang‐Chi Huang, Shih‐Han Wang, Guo‐Chen Fang, Wen‐Cheng Chou, Chun‐Che Liao, Cheng‐Pu Sun, Jia‐Tsrong Jan, Hsiu‐Hua Ma, Hui‐Ying Ko, Yi‐An Ko, Ming‐Tsai Chiang, Jian‐Jong Liang, Chun‐Tse Kuo, Te‐An Lee, Diego Morales‐Scheihing, Chen‐Yang Shen, Shih‐Yu Chen, Louise D. McCullough, Lu Cui, Gerlinde Wernig, Mi‐Hua Tao, Yi‐Ling Lin, Yao‐Ming Chang, Shu‐Ping Wang, Yun‐Ju Lai, Chia‐Wei Li
Publikováno v:
Journal of Medical Virology. 95
Patients with severe COVID-19 often suffer from lymphopenia, which is linked to T cell sequestration, cytokine storm and mortality. However, it remains largely unknown how SARS-CoV-2 induces lymphopenia. Here, we studied the transcriptomic profile an
Autor:
I-Jung Lee, Yu-Hua Lan, Ping-Yi Wu, Yan-Wei Wu, Yu-Hung Chen, Sheng-Che Tseng, Tzu-Jiun Kuo, Cheng-Pu Sun, Jia-Tsrong Jan, Hsiu-Hua Ma, Chun-Che Liao, Jian-Jong Liang, Hui-Ying Ko, Chih-Shin Chang, Wen-Chun Liu, Yi-An Ko, Yen-Hui Chen, Zong-Lin Sie, Szu-I Tsung, Yi-Ling Lin, I-Hsuan Wang, Mi-Hua Tao
Publikováno v:
Emerging Microbes & Infections. 12
Numerous vaccines have been developed to address the current COVID-19 pandemic, but safety, cross-neutralizing efficacy, and long-term protectivity of currently approved vaccines are still important issues. In this study, we developed a subunit vacci
Autor:
Charles Chen, Wei Cheng Lian, Tsun Yung Kuo, Meei Yun Lin, Paula Traquina, Ya-Shan Chuang, Yi Jiun Lin, Jia Tsrong Jan, Yen-Hui Chen, Yu Chiuan Wang, Chia En Lien, John D. Campbell, Chun Che Liao, Luke Tzu Chi Liu, Mi-Hua Tao, Yi-Ling Lin, Yin Shiou Lin, Hsiu Hua Ma, Hui Ying Ko, Ping-Yi Wu, Cheng Pu Sun
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Scientific Reports
Scientific Reports
The COVID-19 pandemic presents an unprecedented challenge to global public health. Rapid development and deployment of safe and effective vaccines are imperative to control the pandemic. In the current study, we applied our adjuvanted stable prefusio
Autor:
Han-Yi Huang, Hsin-Yu Liao, Xiaorui Chen, Szu-Wen Wang, Cheng-Wei Cheng, Md. Shahed-Al-Mahmud, Yo-Min Liu, Arpita Mohapatra, Ting-Hua Chen, Jennifer M. Lo, Yi-Min Wu, Hsiu-Hua Ma, Yi-Hsuan Chang, Ho-Yang Tsai, Yu-Chi Chou, Yi-Ping Hsueh, Ching-Yen Tsai, Pau-Yi Huang, Sui-Yuan Chang, Tai-Ling Chao, Han-Chieh Kao, Ya-Min Tsai, Yen-Hui Chen, Chung-Yi Wu, Jia-Tsrong Jan, Ting-Jen Rachel Cheng, Kuo-I Lin, Che Ma, Chi-Huey Wong
Publikováno v:
Science translational medicine. 14(639)
A major challenge to end the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to develop a broadly protective vaccine that elicits long-term immunity. As the key immunogen, the viral surface spike (S) protein is freq