Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hsiu Chi Ting"'
Double bonds of unsaturated fatty acids differentially regulate mitochondrial cardiolipin remodeling
Autor:
Hsiu-Chi Ting, Li-Tzu Chen, Jo-Yu Chen, Yi-Li Huang, Rui-Cheng Xin, Jui-Fen Chan, Yuan-Hao Howard Hsu
Publikováno v:
Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Supplemented fatty acids can incorporate into cardiolipin (CL) and affect its remodeling. The change in CL species may alter the mitochondrial membrane composition, potentially disturbing the mitochondrial structure and function d
Externí odkaz:
https://doaj.org/article/1a1cc4165ca341799664d426d13316d0
Publikováno v:
BMC Evolutionary Biology, Vol 18, Iss 1, Pp 1-16 (2018)
Abstract Background Mesoderm is generally considered to be a germ layer that is unique to Bilateria, and it develops into diverse tissues, including muscle, and in the case of vertebrates, the skeleton and notochord. Studies on various deuterostome a
Externí odkaz:
https://doaj.org/article/09bbcf52413948838c6dee883983552e
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background The macrophage plays an important role in innate immunity to induce immune responses. Lipid replacement therapy has been shown to change the lipid compositions of mitochondria and potentially becomes an alternative to reduce the i
Externí odkaz:
https://doaj.org/article/ca9790df0f944a0eb2cc3b960aee0c45
Autor:
Claudia Tonelli, Georgi N. Yordanov, Yuan Hao, Astrid Deschênes, Olaf Klingbeil, Hsiu-Chi Ting, Erin Brosnan, Abishek Doshi, Youngkyu Park, Christopher R. Vakoc, Jonathan Preall, David A. Tuveson
Pancreatic ductal adenocarcinoma (PDA) samples reveal extensive cellular heterogeneity. Using single-cell RNA sequencing, we uncover multiple tumor cell populations distinguished by their differentiation state and associated with different stages of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3d85f6a6d909919c37468361d28378b
https://doi.org/10.1101/2022.03.18.484951
https://doi.org/10.1101/2022.03.18.484951
Autor:
Young-Kyu Park, Kenneth Addison, Keith Rivera, Jennifer S Thalappillil, Tobiloba E. Oni, Linda Van Aelst, Nadia V Prasad, Derek K. Cheng, Hsiu-Chi Ting, Darryl J. Pappin, David A. Tuveson, Brinda Alagesan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance For decades, KRAS interactors have been sought after as potential therapeutic targets in KRAS mutant cancers, especially pancreatic ductal adenocarcinoma (PDAC). Our proximity labeling screen with KRAS in PDAC cells highlights RSK1 as a
Abstract 2974: A complex of tumor-suppressor NF1 and SPRED2 promotes pancreatic cancer tumorigenesis
Publikováno v:
Cancer Research. 82:2974-2974
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with poor prognosis due to late detection and lack of effective therapeutic options. >90% of PDAC tumors are driven by activating mutations in the KRAS oncogene, making it an appea
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113680 (2014)
Cell survival from the arrested state can be a cause of the cancer recurrence. Transition from the arrest state to the growth state is highly regulated by mitochondrial activity, which is related to the lipid compositions of the mitochondrial membran
Externí odkaz:
https://doaj.org/article/032c684b68404418bdcfe210c6c05d11
Autor:
Vladimir A. Tyurin, Bing Liu, Peter S. Timashev, Indira H. Shrivastava, Rosário Domingues, Tamil S. Anthonymuthu, Haider H. Dar, Hsiu-Chi Ting, Alexandr A. Kapralov, Rama K. Mallampalli, Claudette M. St. Croix, Qin Yang, Yulia Y. Tyurina, Liubov A. Ponomareva, Dmitry I. Gabrilovich, Karolina Mikulska-Ruminska, Ivet Bahar, Margarita A Artyukhova, Valerian E. Kagan, Galina V. Shurin, Hülya Bayır, Rina Kim, Joel S. Greenberger, Detcho A. Stoyanovsky, Yijen L. Wu, Yuan Gao
Publikováno v:
Nat Chem Biol
Ferroptotic death is the penalty for losing control over three processes-iron metabolism, lipid peroxidation and thiol regulation-that are common in the pro-inflammatory environment where professional phagocytes fulfill their functions and yet surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a3aeb3819d703311e521f88b0ea9c7
https://europepmc.org/articles/PMC7233108/
https://europepmc.org/articles/PMC7233108/
Autor:
Cody J. Freedman, Jennifer M. Bomberger, Becca A. Flitter, Yohei Doi, Janet S. Lee, Erkan Bayir, Gaowei Mao, Joseph M. Pilewski, Indira H. Shrivastava, Matthew R. Parsek, Valerian E. Kagan, Joel S. Greenberger, Abiola F. Ogunsola, Hong Wang, Haider H. Dar, Rama K. Mallampalli, Theodore R. Holman, Tamil S. Anthonymuthu, Simon C. Watkins, Karolina Mikulska-Ruminska, Yulia Y. Tyurina, Jordan R. Gaston, Claudette M. St. Croix, Hsiu Chi Ting, Ivet Bahar, James Krieger, Catherine R. Armbruster, Alexandr A. Kapralov, Hülya Bayır, Vladimir A. Tyurin
Publikováno v:
Journal of Clinical Investigation. 128:4639-4653
Ferroptosis is a death program executed via selective oxidation of arachidonic acid–phosphatidylethanolamines (AA-PE) by 15-lipoxygenases. In mammalian cells and tissues, ferroptosis has been pathogenically associated with brain, kidney, and liver
Autor:
Ching-Yi Lin, Tzu-Pei Fan, Kuang-Tse Wang, Yi-Hsien Su, Yi-Chih Chen, Hsiu-Chi Ting, Jr-Kai Yu
A defining feature of chordates is the unique presence of a dorsal hollow neural tube that forms by internalization of the ectodermal neural plate specified via inhibition of BMP signaling during gastrulation. While BMP controls dorsoventral (DV) pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806f6a61288cd2a6363a91d7cf9f4f7c
https://europepmc.org/articles/PMC6600983/
https://europepmc.org/articles/PMC6600983/