Výsledky vyhledávání - "Hsiou-Chi Liou"

Akademický článek

Targeting metabolism and survival in chronic lymphocytic leukemia and Richter syndrome cells by a novel NF-κB inhibitor

Autor: Tiziana Vaisitti, Federica Gaudino, Samedy Ouk, Maria Moscvin, Nicoletta Vitale, Sara Serra, Francesca Arruga, Johannes L. Zakrzewski, Hsiou-Chi Liou, John N. Allan, Richard R. Furman, Silvia Deaglio

Publikováno v: Haematologica, Vol 102, Iss 11 (2017)

IT-901 is a novel and selective NF-κB inhibitor with promising activity in pre-clinical models. Here we show that treatment of chronic lymphocytic leukemia cells (CLL) with IT-901 effectively interrupts NF-κB transcriptional activity. CLL cells exp

Externí odkaz: https://doaj.org/article/a351e1cc81144e6dbdf1474fed71fa32

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Akademický článek

RNAi-mediated c-Rel silencing leads to apoptosis of B cell tumor cells and suppresses antigenic immune response in vivo.

Autor: Wenzhi Tian, Hsiou-Chi Liou

Publikováno v: PLoS ONE, Vol 4, Iss 4, p e5028 (2009)

c-Rel is a member of the Rel/NF-kappaB transcription factor family and is predominantly expressed in lymphoid and myeloid cells, playing a critical role in lymphocyte proliferation and survival. Persistent activation of the c-Rel signal transduction

Externí odkaz: https://doaj.org/article/2d3354d1182245598cd6a92a01066302

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