Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Hsing-Jang Liu"'
Publikováno v:
Synlett. 25:543-546
A highly stereoselective annulation reaction of 2-cyano-2-cycloalkenones with the Nazarov reagent catalyzed by 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), leading to densely functionalized bicyclic systems, is developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb71a56dc76a2169ff16d7e5c6c8347
https://doi.org/10.1055/s-0033-1340299
https://doi.org/10.1055/s-0033-1340299
Publikováno v:
Synlett. 23:1653-1656
An operationally simple and highly effective annulation process, making use of ZnCl2-catalyzed Michael addition and K2CO3/NaI-induced cyclization as key manipulations, has been developed to construct various bicyclic systems with a high level of func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d868db98e78e79f4c47a1b1cb543fc97
https://doi.org/10.1055/s-0031-1290386
https://doi.org/10.1055/s-0031-1290386
Publikováno v:
Synlett. 2010:3061-3064
A novel total synthesis of laurencenone C, a chamigrene sesquitepenoid natural product, has been accomplished in 11 steps. In the synthetic sequence, the B-ring of the spirocyclic core was constructed by a one-pot operation involving a Knoevenagel co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e23854134607146f31c1f26260ddb6
https://doi.org/10.1055/s-0030-1259052
https://doi.org/10.1055/s-0030-1259052
Publikováno v:
Synthesis. 2010:4242-4250
Lithium naphthalenide (LN)-induced reductive alkylation/addition reactions of aryl-, pyridyl-, and 2-thienyl-substituted dialkylacetonitriles have been investigated. Upon treatment with LN in THF at -40 ˚C, both aryl and pyridyl precursors could und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::199c47fe48b5aa11f6dc15f48be2b9b1
https://doi.org/10.1055/s-0030-1258301
https://doi.org/10.1055/s-0030-1258301
Publikováno v:
European Journal of Organic Chemistry. 2010:4271-4275
Starting from 4,4-dimethyl-2-cyclohexenone, an enantioselective synthesis of (-)-isopisiferin has been accomplished in 15 steps with an overall yield of 11.4 %. This work not only provides synthetic evidence for confirming the absolute configuration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fde20df5a56870d42a8f48a2493247f
https://doi.org/10.1002/ejoc.201000449
https://doi.org/10.1002/ejoc.201000449
Publikováno v:
European Journal of Organic Chemistry. 2010:3473-3480
The total synthesis of natural lignans 5′-methoxyyatein (1), 5′-methoxyclusin (2), and 4′-hydroxycubebinone (3), in racemic form, has been achieved by a newly developed strategy, wherein lithium naphthalenide induced decyanation was employed as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9970af4e31763db2ae662b76fb5d16bc
https://doi.org/10.1002/ejoc.201000318
https://doi.org/10.1002/ejoc.201000318
Publikováno v:
Tetrahedron. 66:871-877
The Diels–Alder reactions of a variety of acyclic α-cyano α,β-unsaturated ketones 8 have been investigated. With the assistance of boron trichloride, these compounds were found to undergo the cycloaddition readily with dienes to give the corresp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13beb8e74e630256d9a7d39c252298d3
https://doi.org/10.1016/j.tet.2009.11.105
https://doi.org/10.1016/j.tet.2009.11.105
Publikováno v:
Journal of the Chinese Chemical Society. 53:1547-1555
The first series of 5'-triazole cytidines la-d and adenosines 2a-c was prepared and evaluated for inhibitory potency toward a-2,3-sialyltransferase. The synthesis of target compounds was achieved by converting the 5'-alcohol of protected nucleosides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a481400168c37f6c6a8ac695f6e8f2
https://doi.org/10.1002/jccs.200600202
https://doi.org/10.1002/jccs.200600202
Publikováno v:
Synlett. :417-420
Making use of a recently developed intramolecular Friedel-Crafts alkylation process as the key operation, the first total synthesis, in racemic form, of pygmaeocin C has been achieved.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7068c1b78afbce586ffcf15c93b7bce1
https://doi.org/10.1055/s-2004-837222
https://doi.org/10.1055/s-2004-837222
Autor:
Chen-Tso Tseng, Shu-Jen Chen, Shin-Ru Shih, Gholam Hossein Hakimelahi, Kak-Shan Shia, Hsing-Jang Liu
Publikováno v:
Medicinal Research Reviews
The absence of effective vaccines for most viral infections highlights an urgent necessity for the design and development of effective antiviral drugs. Due to the advancement in virology since the late 1980s, several key events in the viral life cycl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036b23186922db5bf1f24a1144f5b352
https://doi.org/10.1002/med.10067
https://doi.org/10.1002/med.10067