Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Hsin-wen Chang"'
Autor:
Jared Liu, Hsin-Wen Chang, Robby Grewal, Daniel D. Cummins, Audrey Bui, Kristen M. Beck, Sahil Sekhon, Di Yan, Zhi-Ming Huang, Timothy H. Schmidt, Eric J. Yang, Isabelle M. Sanchez, Mio Nakamura, Shrishti Bhattarai, Quinn Thibodeaux, Richard Ahn, Mariela Pauli, Tina Bhutani, Michael D. Rosenblum, Wilson Liao
Publikováno v:
JID Innovations, Vol 2, Iss 3, Pp 100094- (2022)
The IL-17A inhibitor secukinumab is efficacious for the treatment of psoriasis. To better understand its mechanism of action, we investigated its impact on psoriatic lesions from 15 patients with moderate-to-severe plaque psoriasis undergoing secukin
Externí odkaz:
https://doaj.org/article/1a03535c7ee84f7383f2188a5262f2a2
Autor:
Hsin-Wen Chang, Di Yan, Rasnik Singh, Audrey Bui, Kristina Lee, Alexa Truong, Jeffrey M. Milush, Ma Somsouk, Wilson Liao
Publikováno v:
JID Innovations, Vol 2, Iss 3, Pp 100115- (2022)
Psoriasis is a chronic, inflammatory skin disease that affects 2‒3% of the global population. Besides skin manifestations, patients with psoriasis have increased susceptibility to a number of comorbidities, including psoriatic arthritis, cardiovasc
Externí odkaz:
https://doaj.org/article/4ca4fd47407a45c8b3277afac6d34ca5
Autor:
Samuel Alber, Sugandh Kumar, Jared Liu, Zhi-Ming Huang, Diana Paez, Julie Hong, Hsin-Wen Chang, Tina Bhutani, Lianne S. Gensler, Wilson Liao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Ankylosing spondylitis (AS) is an immune-mediated inflammatory disorder that primarily affects the axial skeleton, especially the sacroiliac joints and spine. This results in chronic back pain and, in extreme cases, ankylosis of the spine. Despite it
Externí odkaz:
https://doaj.org/article/e76897a280d742da817cf559ed5e71a1
Autor:
Jared Liu, Sugandh Kumar, Julie Hong, Zhi-Ming Huang, Diana Paez, Maria Castillo, Maria Calvo, Hsin-Wen Chang, Daniel D. Cummins, Mimi Chung, Samuel Yeroushalmi, Erin Bartholomew, Marwa Hakimi, Chun Jimmie Ye, Tina Bhutani, Mehrdad Matloubian, Lianne S. Gensler, Wilson Liao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Early diagnosis of psoriatic arthritis (PSA) is important for successful therapeutic intervention but currently remains challenging due, in part, to the scarcity of non-invasive biomarkers. In this study, we performed single cell profiling of transcr
Externí odkaz:
https://doaj.org/article/434161d42b6749f3aff3bfd04adb92e7
Autor:
Sithembiso Tiyandza Dlamini, Kyaw Moe Htet, Ei Chue Chue Theint, Wei-Ming Li, Hsin-Wen Chang, Hung-Pin Tu
Publikováno v:
Life, Vol 12, Iss 11, p 1881 (2022)
We investigated the role of vitamin D in the risk of tuberculosis (TB) among patients with end-stage kidney disease (ESKD). The retrospective cohort was conducted with data of 20,985 patients with kidney disease and 20,985 controls without kidney dis
Externí odkaz:
https://doaj.org/article/fdc995f1107c4937a1156e08f155540e
Publikováno v:
Case Studies in Business, Industry & Government Statistics. 2021, Vol. 8, p1-13. 13p.
Publikováno v:
R Journal. Dec2020, Vol. 12 Issue 2, p107-119. 13p.
Autor:
Hsin-Wen Chang, Di Yan, Rasnik Singh, Jared Liu, Xueyan Lu, Derya Ucmak, Kristina Lee, Ladan Afifi, Douglas Fadrosh, John Leech, Kimberly S. Vasquez, Margaret M. Lowe, Michael D. Rosenblum, Tiffany C. Scharschmidt, Susan V. Lynch, Wilson Liao
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-27 (2018)
Abstract Background Psoriasis impacts 1–3% of the world’s population and is characterized by hyper-proliferation of keratinocytes and increased inflammation. At the molecular level, psoriasis is commonly driven by a Th17 response, which serves as
Externí odkaz:
https://doaj.org/article/f8fdd4e7c60946e9b2b66a032d2f0a36
Autor:
Hsin-wen Chang, Ian W. McKeague
Publikováno v:
Journal of the Royal Statistical Society Series B: Statistical Methodology. 84:1947-1968
This paper develops a nonparametric inference framework that is applicable to occupation time curves derived from wearable device data. These curves consider all activity levels within the range of device readings, which is preferable to the practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2bef122bf488a02cc2313311085bd97
https://doi.org/10.1111/rssb.12543
https://doi.org/10.1111/rssb.12543
Autor:
Rasnik K. Singh, Hsin-Wen Chang, Di Yan, Kristina M. Lee, Derya Ucmak, Kirsten Wong, Michael Abrouk, Benjamin Farahnik, Mio Nakamura, Tian Hao Zhu, Tina Bhutani, Wilson Liao
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Recent studies have suggested that the intestinal microbiome plays an important role in modulating risk of several chronic diseases, including inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and cancer. At the s
Externí odkaz:
https://doaj.org/article/d13043be556f4ffdaf12dbfdc4baf729