Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hsin-Yue Tsai"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010869 (2023)
Metabolic pathways are known to sense the environmental stimuli and result in physiological adjustments. The responding processes need to be tightly controlled. Here, we show that upon encountering P. aeruginosa, C. elegans upregulate the transcripti
Externí odkaz:
https://doaj.org/article/111b29fbc95a4d84a0fafa0175493d41
Autor:
Chia-Ching Lin, Yi-Ru Shen, Chi-Chih Chang, Xiang-Yi Guo, Yun-Yun Young, Ting-Yu Lai, I-Shing Yu, Chih-Yuan Lee, Tsung-Hsien Chuang, Hsin-Yue Tsai, Li-Chung Hsu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Terminal uridyltransferase 7 (TUT7) adds U-tails on diverse RNAs to promote degradation. Here the authors show that TUT7 is induced upon LPS treatment in macrophages and promotes decay of Regnase-1, thereby regulating the expression of a subset of cy
Externí odkaz:
https://doaj.org/article/e58f9225379f4a8285ee08d23b8361aa
Publikováno v:
Science Advances. 8
Small RNAs regulate spermatogenesis across species ranging from Caenorhabditis elegans to humans. In C. elegans , two Argonaute proteins, ALG-3 and ALG-4, and their associated alg-3/4 26G-small RNAs are essential for spermiogenesis at 25°C. The alg-
Publikováno v:
Science advances. 8(32)
Small RNAs regulate spermatogenesis across species ranging from
Autor:
Chi-Chih Chang, Chia-Ching Lin, Li-Chung Hsu, Yi-Ru Shen, Tsung-Hsien Chuang, Ting-Yu Lai, I-Shing Yu, Chih-Yuan Lee, Hsin-Yue Tsai, Xiang-Yi Guo, Yun-Yun Young
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications
Nature Communications
Different levels of regulatory mechanisms, including posttranscriptional regulation, are needed to elaborately regulate inflammatory responses to prevent harmful effects. Terminal uridyltransferase 7 (TUT7) controls RNA stability by adding uridines t
Autor:
Ting-Ying Huang, Jin-Chuan Sheu, Huai-Jen Tsai, Cheng-Yung Lin, Hung-Chieh Lee, Jia-Rung Hu, Hsin-Yue Tsai, Chuan-Yang Fu, Kai-Yin Lo
Publikováno v:
The EMBO Journal
Upstream open reading frames (uORFs) are known to negatively affect translation of the downstream ORF. The regulatory proteins involved in relieving this inhibition are however poorly characterized. In response to cellular stress, eIF2α phosphorylat
Publikováno v:
Science Advances. 8/12/2022, Vol. 8 Issue 32, p1-15. 15p.
Publikováno v:
Journal of the American Chemical Society. 138(7)
The mechanism of DNA polymerase (pol) fidelity is of fundamental importance in chemistry and biology. While high-fidelity pols have been well studied, much less is known about how some pols achieve medium or low fidelity with functional importance. H
Publikováno v:
RNA Biology
Ribosome biogenesis governs protein synthesis. NIFK is transactivated by c-Myc, the key regulator of ribosome biogenesis. The biological function of human NIFK is not well established, except that it has been shown to interact with Ki67 and NPM1. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a24d7ab8982674d20924cbc3abb2404
Publikováno v:
Proceedings of the National Academy of Sciences. 103:16147-16152
RNase P, which catalyzes the magnesium-dependent 5′-end maturation of tRNAs in all three domains of life, is composed of one essential RNA and a varying number of protein subunits depending on the source: at least one in bacteria, four in archaea,