Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hsin-Yao Tsai"'
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
ObjectiveSchizophrenia is a chronic debilitating neurobiological disorder of aberrant synaptic connectivity and synaptogenesis. Postsynaptic density (PSD)–related proteins in N-methyl-D-aspartate receptor–postsynaptic signaling complexes are cruc
Externí odkaz:
https://doaj.org/article/0bfb7ddbc75f43d99cdec9b3867e3a32
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4498 (2022)
Arc/Arg3.1 (activity-regulated cytoskeletal-associated protein (ARC)) is a critical regulator of long-term synaptic plasticity and is involved in the pathophysiology of schizophrenia. The functions and mechanisms of human ARC action are poorly unders
Externí odkaz:
https://doaj.org/article/e202d6d433254e3f875b3b514788049e
Autor:
Tsung-Ming Hu, Hsiang-Sheng Chung, Lieh-Yung Ping, Shih-Hsin Hsu, Hsin-Yao Tsai, Shaw-Ji Chen, Min-Chih Cheng
Publikováno v:
Brain Sciences, Vol 10, Iss 8, p 545 (2020)
Valproic acid (VPA) is a multifunctional medication used for the treatment of epilepsy, mania associated with bipolar disorder, and migraine. The pharmacological effects of VPA involve a variety of neurotransmitter and cell signaling systems, but the
Externí odkaz:
https://doaj.org/article/97eae980d52948ee945ccc73959121ca
Autor:
Jun-Ming Li, Chao-Lin Lu, Min-Chih Cheng, Sy-Ueng Luu, Shih-Hsin Hsu, Tsung-Ming Hu, Hsin-Yao Tsai, Chia-Hsiang Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85373 (2014)
Aberrant synaptic dysfunction is implicated in the pathogenesis of schizophrenia. The DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 (SAPAP2) located at the post-synaptic density of neuronal cells is involved in the neuronal synaptic func
Externí odkaz:
https://doaj.org/article/2bec6857ddc84dc684adf701675b0846
Autor:
Hsin-Yao Tsai, 蔡心堯
94
The wind-wave numerical model was broadly applied to wave prediction. A discussion of the effect due to wind, tide, and current is proceeded by SWAN model which the tide and current data are simulated by POM model. The variation of the wave h
The wind-wave numerical model was broadly applied to wave prediction. A discussion of the effect due to wind, tide, and current is proceeded by SWAN model which the tide and current data are simulated by POM model. The variation of the wave h
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/28634032184632576308
Publikováno v:
Psychiatric genetics. 33(1)
The alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors significantly regulate the synaptic transmission and functions of various synaptic receptors. This study aimed to identify single nucleotide mutations in the glutamate recepto
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 5; Pages: 783
Schizophrenia is a complex mental disorder with a genetic component. The GRIK gene family encodes ionotropic glutamate receptors of the kainate subtype, which are considered candidate genes for schizophrenia. We screened for rare and pathogenic mutat
Autor:
Fu-Yu Cheng, Shih-Hsin Hsu, Min-Chih Cheng, Shaw-Ji Chen, Ying-Chieh Wang, Hsin-Yao Tsai, Chia-Hsiang Chen
Publikováno v:
Schizophrenia research. 235
Publikováno v:
Psychiatry research. 300
GNB1L haploinsufficiency caused by 22q11.2 deletion syndrome may contribute to schizophrenia pathophysiology. We resequenced the protein-coding sequences of GNB1L in 553 patients with schizophrenia and 535 controls from Taiwan. Four common single-nuc
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics, Vol 11 (2020)
ObjectiveSchizophrenia is a chronic debilitating neurobiological disorder of aberrant synaptic connectivity and synaptogenesis. Postsynaptic density (PSD)–related proteins in N-methyl-D-aspartate receptor–postsynaptic signaling complexes are cruc