Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hsin-Sheng Wang"'
Autor:
Yu-Sheng Chao, Wen-Tai Li, Chungming Chang, Ching Ping Chen, Heng Liang Lin, Hsin Sheng Wang, Chiung-Tong Chen, Chen Lung Huang, Chu Chung Lin, Chien-Chang Shen, Jen Shin Song, Chi Hung Lin, Huan Yi Tseng, Tung Wei Chen, Jiunn Jye Chuu, Der Ren Hwang, Chih Bo Hu, Chiung Yi Huang
Publikováno v:
Journal of Medicinal Chemistry. 53:2409-2417
2-Amino-1-arylidenaminoimidazoles, a novel class of orally (po) active microtubule-destabilizing anticancer agents, were synthesized. The compounds were designed from a hit compound identified in a drug discovery platform by using cancer cell-based h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4813c824d6ab69512226f2b0400c351
https://doi.org/10.1021/jm901501s
https://doi.org/10.1021/jm901501s
Autor:
Chien-Ming Li, Tien-Yi Lee, Yu-Sheng Chao, Chi-Yen Chang, Teng-Kuang Yeh, Hsin-Sheng Wang, Chiung-Tong Chen, Chen-Lung Huang, Jiuun-Jye Chuu, Ching-Ping Chen, Chin-Tarng Lin, Chungming Chang, Jang Yang Chang, Chien-Chang Shen
Publikováno v:
Pharmacological Research. 61:108-115
DB-67 and its lactone homolog DB-91 are derivatives of topoisomerase I inhibitor camptothecin (CPT) with silyl moiety, which may exhibit a slower inactivation process by changed kinetics of protein binding and/or hydrolysis of its lactone ring and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8750e202453d27f4cc1b23f063c32b4f
https://doi.org/10.1016/j.phrs.2009.07.005
https://doi.org/10.1016/j.phrs.2009.07.005
Autor:
Chung-Nien Chang, Yen-Ting Yeh, Ting-Yueh Tsai, Mohane Selvaraj Coumar, Hsu Tsu, Weir-Torn Jiaang, Su-Ying Wu, Ying-Ying Chang, Yuan-Shou Chen, Ke-Ta Lin, Shiow-Ju Lee, Ssu-Hui Wu, Wei Cheng Chen, Hsing Pang Hsieh, Yu-Sheng Chao, Hsin-Sheng Wang, Chiung-Tong Chen, Kuo-His Kao, I-Lin Lu, Chia-Hui Chien, Xin Chen
Publikováno v:
Journal of Medicinal Chemistry. 49:373-380
Dipeptidyl peptidase IV (DPP-IV) inhibitors are expected to become a new type of antidiabetic drugs. Most known DPP-IV inhibitors often resemble the dipeptide cleavage products, with a proline mimic at the P1 site. As off-target inhibitions of DPP8 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2331bd9789f263cefe4020c050cead5
https://doi.org/10.1021/jm0507781
https://doi.org/10.1021/jm0507781
Publikováno v:
ASSAY and Drug Development Technologies. 2:31-38
Angiogenesis plays a major role in many physiological and pathological processes. Pathological development of diseased conditions like growth and metastasis of solid tumors and psoriasis is associated with angiogenesis. Assays developed, thus far, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a9fb5bdedd4ab09d997561f38c1153
https://doi.org/10.1089/154065804322966298
https://doi.org/10.1089/154065804322966298
Autor:
Ching-Ping, Chen, Chih-Bo, Hu, Kai-Chia, Yeh, Jen-Shin, Song, Teng-Kuang, Yeh, Fei-Feng, Tung, Ling-Ling, Hwang, Huan-Yi, Tseng, Yu-Chen, Huang, Horng-Shing, Shy, Su-Huei, Hsieh, Chien-Chang, Shen, Hsin-Sheng, Wang, Hsing-Pang, Hsieh, Jing-Ping, Liou, Yu-Sheng, Chao, Chiung-Tong, Chen
Publikováno v:
Anticancer research. 30(7)
Antimitotic tubulin-binding BPR0L075 is structurally analogous to the vascular-disrupting combretastatin A-4.In vitro/in vivo models of endothelial cells cultures, Matrigel plug assay, tumor-bearing nude mice, and murine leukemia cells-inoculated mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b405b895e6900337a3c961ae3e9ab5b2
https://pubmed.ncbi.nlm.nih.gov/20683017
https://pubmed.ncbi.nlm.nih.gov/20683017
Autor:
Chen-Lung Huang, Mei-Hua Tsou, Chiung-Tong Chen, Hsin-Sheng Wang, Jiunn-Jye Chuu, Jacqueline Ming Liu, Ching-Ping Chen
Publikováno v:
Journal of biomedical science. 14(2)
Cancer has been the leading cause of death in Taiwan over the past two decades and liver cancer is the leading cause of all cancer deaths in Taiwan with a trend of increase in incidence. Therapeutic options and efficacy for liver cancer have been lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04c367efbff8753dac2709fb8dcaa1a
https://pubmed.ncbi.nlm.nih.gov/17206490
https://pubmed.ncbi.nlm.nih.gov/17206490
Autor:
Jiunn-Jye Chuu, Liu, Jacqueline Ming, Mei-Hua Tsou, Chen-Lung Huang, Ching-Ping Chen, Hsin-Sheng Wang, Chiung-Tong Chen
Publikováno v:
Journal of Biomedical Science; Mar2007, Vol. 14 Issue 2, p233-244, 12p, 1 Color Photograph, 3 Graphs
Publikováno v:
Assay & Drug Development Technologies; Feb2004, Vol. 2 Issue 1, p31-38, 8p