Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Hsin-Kai Liao"'
Autor:
Yanjiao Shao, Canzhao Liu, Hsin-Kai Liao, Ran Zhang, Baolei Yuan, Hanyan Yang, Ronghui Li, Siting Zhu, Xi Fang, Concepcion Rodriguez Esteban, Ju Chen, Juan Carlos Izpisua Belmonte
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Dilated cardiomyopathy (DCM) is one of the most common causes of heart failure. Multiple identified mutations in nexilin (NEXN) have been suggested to be linked with severe DCM. However, the exact association between multiple muta
Externí odkaz:
https://doaj.org/article/11999baaed2c4ab9b5d8511020581917
Autor:
Haisong Liu, Ronghui Li, Hsin-Kai Liao, Zheying Min, Chao Wang, Yang Yu, Lei Shi, Jiameng Dan, Alberto Hayek, Llanos Martinez Martinez, Estrella Nuñez Delicado, Juan Carlos Izpisua Belmonte
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Human pluripotent stem cell (hPSC) derived pancreatic beta cells are a promising and potentially limitless source for cell replacement therapy. Here the authors perform stage-wise chemical screening to develop an improved protocol for hPSC differenti
Externí odkaz:
https://doaj.org/article/e0538b6a302e489391b9de003c23bba8
Autor:
Chao Wang, Ruben Rabadan Ros, Paloma Martinez-Redondo, Zaijun Ma, Lei Shi, Yuan Xue, Isabel Guillen-Guillen, Ling Huang, Tomoaki Hishida, Hsin-Kai Liao, Estrella Nuñez Delicado, Concepcion Rodriguez Esteban, Pedro Guillen-Garcia, Pradeep Reddy, Juan Carlos Izpisua Belmonte
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Short term systemic expression of the reprogramming factors Oct-3/4, Sox2, Klf4, c-Myc (OSKM) rejuvenates aging cells and promotes tissue regeneration. Here the authors show that myofiber-specific expression of OSKM accelerates muscle regeneration by
Externí odkaz:
https://doaj.org/article/ec46029f8e914da49e6eeddd4f0bc4ed
Autor:
Noriko Ichino, MaKayla R Serres, Rhianna M Urban, Mark D Urban, Anthony J Treichel, Kyle J Schaefbauer, Lauren E Tallant, Gaurav K Varshney, Kimberly J Skuster, Melissa S McNulty, Camden L Daby, Ying Wang, Hsin-kai Liao, Suzan El-Rass, Yonghe Ding, Weibin Liu, Jennifer L Anderson, Mark D Wishman, Ankit Sabharwal, Lisa A Schimmenti, Sridhar Sivasubbu, Darius Balciunas, Matthias Hammerschmidt, Steven Arthur Farber, Xiao-Yan Wen, Xiaolei Xu, Maura McGrail, Jeffrey J Essner, Shawn M Burgess, Karl J Clark, Stephen C Ekker
Publikováno v:
eLife, Vol 9 (2020)
One key bottleneck in understanding the human genome is the relative under-characterization of 90% of protein coding regions. We report a collection of 1200 transgenic zebrafish strains made with the gene-break transposon (GBT) protein trap to simult
Externí odkaz:
https://doaj.org/article/304fac055ae14ae1937ee0f79c8cd7bc
Autor:
Jui-Chieh Chen, Li-Li Chiu, Kuang-Lun Lee, Wei-Ning Huang, Jiing-Guang Chuang, Hsin-Kai Liao, Lu-Ping Chow
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34627 (2012)
BACKGROUND: Pen c 13, identified as a 33-kDa alkaline serine protease, is a major allergen secreted by Penicillium citrinum. Detailed knowledge about the epitopes responsible for IgE binding would help inform the diagnosis/prognosis of fungal allergy
Externí odkaz:
https://doaj.org/article/36561fd002a24ad1921f62a6b4052456
Autor:
Maura McGrail, Julia M Hatler, Xianyan Kuang, Hsin-Kai Liao, Kishore Nannapaneni, Kristin E Noack Watt, Juli D Uhl, David A Largaespada, Erik Vollbrecht, Todd E Scheetz, Adam J Dupuy, Jesse M Hostetter, Jeffrey J Essner
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18826 (2011)
Large-scale sequencing of human cancer genomes and mouse transposon-induced tumors has identified a vast number of genes mutated in different cancers. One of the outstanding challenges in this field is to determine which genes, when mutated, contribu
Externí odkaz:
https://doaj.org/article/2527c50033bc4acc9c059bfb44b5c54e
Autor:
Hsin-Kai Liao, 廖信凱
97
The criterion for the fruit harvesting depends on the maturity of the fruit, blight and infection. The experiences of farmers based on the appearance of the fruit and the intuition of them are usually employed to evaluate the harvesting time
The criterion for the fruit harvesting depends on the maturity of the fruit, blight and infection. The experiences of farmers based on the appearance of the fruit and the intuition of them are usually employed to evaluate the harvesting time
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/61261766180660708471
Autor:
Hsin-Kai Liao, 廖信凱
88
Allergic patients tend to mount immunoglobulin E responses against allergens that originate from pollen, mites, animal dander and molds. These allergic patients with specific IgE antibodies show severe clinical symptoms (allergic rhinitis, co
Allergic patients tend to mount immunoglobulin E responses against allergens that originate from pollen, mites, animal dander and molds. These allergic patients with specific IgE antibodies show severe clinical symptoms (allergic rhinitis, co
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/69145262424363558438
Autor:
Llanos Martinez Martinez, Zheying Min, Alberto Hayek, Haisong Liu, Estrella Nuñez Delicado, Lei Shi, Chao Wang, Ronghui Li, Juan Carlos Izpisua Belmonte, Jiameng Dan, Hsin-Kai Liao, Yang Yu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Human pluripotent stem cell (hPSC)-derived pancreatic β cells are an attractive cell source for treating diabetes. However, current derivation methods remain inefficient, heterogeneous, and cell line dependent. To address these issues, we first devi
Autor:
Concepcion Rodriguez Esteban, Juan Carlos Izpisua Belmonte, Ruben Rabadan Ros, Pedro Guillén-García, Tomoaki Hishida, Pradeep Reddy, Ling Huang, Yuan Xue, Hsin Kai Liao, Isabel Guillen-Guillen, Lei Shi, Chao Wang, Zaijun Ma, Paloma Martinez-Redondo, Estrella Nuñez Delicado
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Short-term, systemic expression of the Yamanaka reprogramming factors (Oct-3/4, Sox2, Klf4 and c-Myc [OSKM]) has been shown to rejuvenate aging cells and promote tissue regeneration in vivo. However, the mechanisms by which OSKM promotes tissue regen