Prognostic Significance of O-GlcNAc and PKM2 in Hormone Receptor-Positive and HER2-Nonenriched Breast Cancer

Autor: Wen-Ling Kuo, Lin-Lu Tseng, Che-Chang Chang, Chih-Jung Chen, Mei-Ling Cheng, Hsin-Hung Cheng, Meng-Jen Wu, Yu-Lun Chen, Ruei-Ting Chang, Hsiang-Yu Tang, Yong-Chen Hsu, Wen-Jye Lin, Cheng-Yuan Kao, Wen-Ping Hsieh, Hsing-Jien Kung, Wen-Ching Wang

Publikováno v: Diagnostics, Vol 11, Iss 8, p 1460 (2021)

Predictive metabolic biomarkers for the recurrent luminal breast cancer (BC) with hormone receptor (HR)-positive and human epidermal growth factor receptor type 2 (HER2)-negative are lacking. High levels of O-GlcNAcylation (O-GlcNAc) and pyruvate kin

Externí odkaz: https://doaj.org/article/6fd67ce731a940518ea085135d1a71b6

Targeting the histone demethylase PHF8-mediated PKCα-Src-PTEN axis in HER2-negative gastric cancer

Autor: Ta Sen Yeh, Shih Chiang Huang, Wen-Ching Wang, Hsin Hung Cheng, Ya Yun Syu, Lin Lu Tseng, Chiou-Hwa Yuh, Hsing Jien Kung, Chih Pin Chuu

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Significance Gastric cancer (GC), a deadly malignancy in the world, particularly in East Asia, remains a major clinical challenge given a lack of effective targeted treatments for advanced HER2-negative cases (80 to 88%). This work uncovers a PHF8/c-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d6267c68403e89831f8f44441e7234
https://doi.org/10.1073/pnas.1919766117

Development of a strategic policy for unmanned autonomous ships: a study on Taiwan

Autor: Kwan Ouyang, Hsin-Hung Cheng

Publikováno v: Maritime Policy & Management. 48:316-330

This study established a model for developing a strategic policy for unmanned autonomous ships. The decision matrix was used to develop policy programs, and SWOT analysis was employed to summarize ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62827aa3342c8c46809833e3095c3733
https://doi.org/10.1080/03088839.2020.1768315

Prognostic Significance of O-GlcNAc and PKM2 in Hormone Receptor-Positive and HER2-Nonenriched Breast Cancer

Autor: Meng Jen Wu, Yong Chen Hsu, Hsin Hung Cheng, Mei Ling Cheng, Yu Lun Chen, Chih Jung Chen, Wen-Ping Hsieh, Wen-Ching Wang, Hsing Jien Kung, Cheng Yuan Kao, Hsiang Yu Tang, Lin Lu Tseng, Che Chang Chang, Wen Jye Lin, Wen Ling Kuo, Ruei Ting Chang

Publikováno v: Diagnostics
Volume 11
Issue 8
Diagnostics, Vol 11, Iss 1460, p 1460 (2021)

Predictive metabolic biomarkers for the recurrent luminal breast cancer (BC) with hormone receptor (HR)-positive and human epidermal growth factor receptor type 2 (HER2)-negative are lacking. High levels of O-GlcNAcylation (O-GlcNAc) and pyruvate kin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59493dccb344e2c8e567b1da5b4ef6af

KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis

Autor: Wei Yang Sit, Ta Sen Yeh, Meng Chen Wu, Chih Pin Chuu, Tsan Jan Chen, Hsing Jien Kung, Hsin Hung Cheng, Wen-Ching Wang, Yi Chen Li, Shu Chien

Publikováno v: Cell death & disease, vol 10, iss 2
Wu, Meng-Chen; Cheng, Hsin-Hung; Yeh, Ta-Sen; Li, Yi-Chen; Chen, Tsan-Jan; Sit, Wei Yang; et al.(2019). KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis.. Cell death & disease, 10(2), 68. doi: 10.1038/s41419-019-1305-y. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/4gf145s4
Cell Death and Disease, Vol 10, Iss 2, Pp 1-15 (2019)
Cell Death & Disease

KDM4/JMJD2 Jumonji C-containing histone lysine demethylases (KDM4A–D) constitute an important class of epigenetic modulators in the transcriptional activation of cellular processes and genome stability. Interleukin-8 (IL-8) is overexpressed in gast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f65763fdbc7191beeb0f61e1986f60
https://escholarship.org/uc/item/4gf145s4