Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hsin Hsueh Shen"'
Autor:
Hsin Hsueh Shen, Stephen J. Peterson, Lars Bellner, Abu Choudhary, Lior Levy, Leah Gancz, Ariel Sasson, Joseph Trainer, Rita Rezzani, Abraham Resnick, David E. Stec, Nader G. Abraham
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 489 (2020)
Excessive lipid accumulation in white adipose tissue (WAT) results in adipocyte hypertrophy and chronic low-grade inflammation, which is the major cause of obesity-associated insulin resistance and consequent metabolic disease. The development of bei
Externí odkaz:
https://doaj.org/article/03d85f2dfcdf48f38702a1bc3f5b5d7a
Autor:
Shieh-Yang Huang, Ming-Ting Chung, Ching-Wen Kung, Shu-Ying Chen, Yi-Wen Chen, Tong Pan, Pao-Yun Cheng, Hsin-Hsueh Shen, Yen-Mei Lee
Publikováno v:
Journal of Obesity & Metabolic Syndrome, Vol 33, Iss 2, Pp 177-188 (2024)
Background : AMP-activated protein kinase (AMPK) is a key enzyme for cellular energy homeostasis and improves metabolic disorders. Brown and beige adipose tissues exert thermogenesis capacities to dissipate energy in the form of heat. Here, we invest
Externí odkaz:
https://doaj.org/article/d4b5a6e3db3d413f96a5229e58304255
Publikováno v:
Journal of Medical Sciences, Vol 41, Iss 3, Pp 146-152 (2021)
Background: Estrogen deficiency is one of the main causes of cardiovascular diseases (CVDs) after menopause, accompanied with the upregulation of oxidative stress. Two isoforms of heme oxygenase (HO), HO-1 and HO-2, have been implicated in the cytopr
Externí odkaz:
https://doaj.org/article/fbc4417c527642c5a321e45a74946d19
Autor:
Je-Ming Hu, Chih-Hsueng Hsu, Yu-Chun Lin, Ching-Wen Kung, Shu-Ying Chen, Wen-Ting Lin, Pao-Yun Cheng, Hsin-Hsueh Shen, Yen-Mei Lee
Publikováno v:
International Journal of Hyperthermia, Vol 38, Iss 1, Pp 862-874 (2021)
Objective: Heat stroke (HS) elicits the systemic inflammatory responses that result in multiple organ dysfunction (MOD). Heat shock response and autophagy are activated during heat stress for removal of damaged organelles and proteins, emerging as a
Externí odkaz:
https://doaj.org/article/9ac4aaaf7ceb4066b8be6bcbb84fa04a
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Sepsis is defined as a life-threatening organ dysfunction syndrome with high morbidity and mortality caused by bacterial infection. The major characteristics of sepsis are systemic inflammatory responses accompanied with elevated oxidative stress, le
Externí odkaz:
https://doaj.org/article/96dba3e0499f403c888cc070e257ba5d
Autor:
Maayan Waldman, Shailendra P. Singh, Hsin-Hsueh Shen, Ragin Alex, Rita Rezzani, Gaia Favero, Edith Hochhauser, Ran Kornowski, Michael Arad, Stephen J. Peterson
Publikováno v:
Cells, Vol 11, Iss 19, p 3060 (2022)
Objective: NOV/CCN3 is an adipocytokine recently linked to obesity, insulin resistance, and cardiometabolic dysfunction. NOV is manufactured and secreted from adipose tissue, with blood levels highly correlated with BMI. NOV levels are increased in o
Externí odkaz:
https://doaj.org/article/9bec420800fe42f580535701fc370b2a
Autor:
Hsin-Hsueh Shen, Chien-Yi Yang, Ching-Wen Kung, Shu-Ying Chen, Hong-Min Wu, Pao-Yun Cheng, Kwok-Keung Lam, Yen-Mei Lee
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-12 (2019)
Abstract Background Loss of ovarian function, as in menopause or after ovariectomy (OVX), is closely associated with obesity and white adipose tissue (WAT) inflammation. Estrogen replacement protects against postmenopausal obesity but increases the r
Externí odkaz:
https://doaj.org/article/e01a016ffc074400932849e3def5051b
Autor:
Hsin-Hsueh Shen, Yu-Shiuan Tseng, Ni-Chun Kuo, Ching-Wen Kung, Sherif Amin, Kwok-Keung Lam, Yen-Mei Lee
Publikováno v:
Mediators of Inflammation, Vol 2019 (2019)
Heat stroke (HS) is a life-threatening illness and defined as when body temperature elevates above 40°C accompanied by the systemic inflammatory response syndrome that results in multiple organ dysfunctions. α-Lipoic acid (ALA) acts as a cofactor o
Externí odkaz:
https://doaj.org/article/3dde23c7962e47b280a64bba9cef975c
Publikováno v:
Antioxidants, Vol 9, Iss 10, p 924 (2020)
Magnolol (MG) is the main active compound of Magnolia officinalis and exerts a wide range of biological activities. In this study, we investigated the effects of MG using tyloxapol (Tylo)-induced (200 mg/kg, i.p.) hyperlipidemia in rats and palmitic
Externí odkaz:
https://doaj.org/article/5f5d32e737fc47cab1445c4163a0ebfc
Autor:
Marco Raffaele, Maria Licari, Sherif Amin, Ragin Alex, Hsin-hsueh Shen, Shailendra P. Singh, Luca Vanella, Rita Rezzani, Francesca Bonomini, Stephen J. Peterson, David E. Stec, Nader G. Abraham
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5469 (2020)
Aim: Obesity is associated with metabolic syndrome, hypertension, dyslipidemia, nonalcoholic fatty liver disease (NAFLD), and type 2 diabetes. In this study, we investigated whether the dietary supplementation of pomegranate seed oil (PSO) exerted a
Externí odkaz:
https://doaj.org/article/321f47741d0b4829b4f7a5c7f500019f