Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Hsien-Sheng Yin"'
Autor:
Wan-Xuan Ho, Wen-Ting Chen, Chih-Hsuan Lien, Hsin-Yu Yang, Kuan-Hung Chen, Yu-Fan Wei, Meng-Han Wang, I-Ting Ko, Fan-Gang Tseng, Hsien-Sheng Yin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9959 (2022)
We previously developed chicken interleukin-1β (IL-1β) mutants as single-dose adjuvants that induce protective immunity when co-administered with an avian vaccine. However, livestock such as pigs may require a vaccine adjuvant delivery system that
Externí odkaz:
https://doaj.org/article/149448dcdfef4926bf619d9c0ef42f6f
Autor:
Wen-Ting Chen, Hsin-Yu Yang, Chih-Yu Lin, Yi-Zong Lee, Szu-Chin Ma, Wei-Cheng Chen, Hsien-Sheng Yin
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1671 (2020)
Glutamine synthetase (GS) catalyzes the condensation of ammonia and glutamate, along with ATP, to form glutamine. Despite extensive studies on GSs from eukaryotes and prokaryotes, the roles of the N-terminus and other structural features in catalysis
Externí odkaz:
https://doaj.org/article/e1971c8dde6745dfa6d173245acade5a
Autor:
Wen-Ting Chen, Yi-Le Wu, Ting Chen, Chao-Sheng Cheng, Hong-Lin Chan, Hsiu-Chuan Chou, Yi-Wen Chen, Hsien-Sheng Yin
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92154 (2014)
BACKGROUND: Avian reovirus (ARV) is a member of the Orthoreovirus genus in the Reoviridae family. It is the etiological agent of several diseases, among which viral arthritis and malabsorption syndrome are the most commercially important, causing con
Externí odkaz:
https://doaj.org/article/6bcc349b5bbc488abc6f16a101aa8178
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74271 (2013)
Helicobacter pylori is a major etiologic agent associated with the development and maintenance of human gastritis. The goal of this study was to develop novel antibiotics against H. pylori, and we thus targeted H. pylori phosphopantetheine adenylyltr
Externí odkaz:
https://doaj.org/article/e32793031e884074a8590a198b978139
Publikováno v:
Biochemical and Biophysical Research Communications. 477:794-800
Helicobacter pylori is a notorious human pathogen and the appearance of antibiotic resistance of this bacterium has posed a serious threat to human health. Lipopolysaccharide (LPS) is a key virulence factor and plays important roles in pathogenesis o
Autor:
Hsien-Sheng Yin1,2, Xiaolin Wn2, Paterson, Reay G.2, Lamb, Robert A.1,2, Jardetzky, Theodore S.2
Publikováno v:
Nature. 1/5/2006, Vol. 439 Issue 7072, p38-44. 7p. 5 Diagrams, 1 Chart.
Autor:
Lee-Wei Yang, Emmanuel Oluwatobi Salawu, Ting Chen, Xinquan Wang, Wen-Ting Chen, Yuan-Yu Chang, Shih-Che Sue, Hsien-Sheng Yin, Dongli Wang, Yi-Zong Lee, Wen-Yang Huang
Publikováno v:
Scientific Reports
Receptor-binding and subsequent signal-activation of interleukin-1 beta (IL-1β) are essential to immune and proinflammatory responses. We mutated 12 residues to identify sites important for biological activity and/or receptor binding. Four of these
Autor:
Yu-Wen Chen, Ping-Chiang Lyu, Yong-Chun Luo, Chao-Sheng Cheng, Wen-Ting Chen, Hsien-Sheng Yin, Chih-Hao Chen
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 30:488-502
Phosphopantetheine adenylyltransferase (PPAT) catalyses the penultimate step in coenzyme A biosynthesis in bacteria and is therefore a candidate target for antibacterial drug development. We randomly mutated the residues in the Helicobacter pylori PP
Publikováno v:
Process Biochemistry. 45:1057-1064
The single chain chicken interleukin-12 (chIL-12)- or mature chIL-18-encoding region was cloned into the nonessential gene F11L of fowlpox virus (FPV) to generate the recombinant (r) FPV/chIL-12 (rFPV/chIL-12) or rFPV/chIL-18 for rchIL-12 or rchIL-18
Publikováno v:
Journal of General Virology. 88:1797-1805
Analysis of the amino acid sequence of core protein μA of avian reovirus has indicated that it may share similar functions to protein μ2 of mammalian reovirus. Since μ2 displayed both nucleotide triphosphatase (NTPase) and RNA triphosphatase (RTPa