Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Hsien‐Sung Huang"'
Autor:
Tzu-Yu Chen, Shuan-Pei Lin, De-Fong Huang, Hsien-Sung Huang, Feng-Chiao Tsai, Li-Jen Lee, Hsiang-Yu Lin, Hsiang-Po Huang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-18 (2024)
Abstract Mucopolysaccharidosis (MPS) type II is caused by a deficiency of iduronate-2-sulfatase and is characterized by the accumulation of glycosaminoglycans (GAGs). Without effective therapy, the severe form of MPS II causes progressive neurodegene
Externí odkaz:
https://doaj.org/article/e529a6b8ed7e46a396c2e19ae032fe0f
Autor:
Ming-Yi Chou, Xuhui Cao, Kuan-Chu Hou, Meng-Han Tsai, Chih-Yu Lee, Meng-Fai Kuo, Vin-Cent Wu, Hsin-Yi Huang, Schahram Akbarian, Sheng-Kai Chang, Chung-Yi Hu, Shu-Wha Lin, Hsien-Sung Huang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Knockout of Mir125b-2 in mice leads to defects in hippocampus-related behaviors and affects hippocampal expression of Grin2a and NMDAR-mediated currents.
Externí odkaz:
https://doaj.org/article/77e4e7f104cc405f84d150a69a607e3a
Autor:
Hsin-Hsiung Chen, Hao-Yu Lu, Chao-Hsin Chang, Shih-Hao Lin, Chu-Wei Huang, Po-Han Wei, Yi-Wen Chen, Yi-Rou Lin, Hsien-Sung Huang, Pei-Yu Wang, Yeou-Ping Tsao, Show-Li Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Breast carcinoma-amplified sequence 2 (BCAS2) regulates β-catenin gene splicing. The conditional knockout of BCAS2 expression in the forebrain (BCAS2 cKO) of mice confers impaired learning and memory along with decreased β-caten
Externí odkaz:
https://doaj.org/article/ff43f430a06d49728dfe6ec84acac4b6
Publikováno v:
Cell Reports, Vol 21, Iss 8, Pp 2264-2276 (2017)
Mammalian olfactory bulbs (OBs) require continuous replenishment of interneurons (mainly granule cells [GCs]) to support local circuits throughout life. Two spatiotemporally distinct waves of postnatal neurogenesis contribute to expanding and maintai
Externí odkaz:
https://doaj.org/article/ae05738886c249a897e804972fdc79a7
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192355 (2018)
RBFOX3/NeuN is a neuronal splicing regulator involved in neural circuitry balance, as well as neurogenesis and synaptogenesis. Rbfox3 is expressed in neurons; however, in the retina, expression is restricted to cells in the ganglion cell layer and so
Externí odkaz:
https://doaj.org/article/5e4839540e28454d8fbe5c016a44cf98
Autor:
Chia-Yi Lin, Shih-Chuan Huang, Chun-Che Tung, Chih-Hsuan Chou, Susan Shur-Fen Gau, Hsien-Sung Huang
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163663 (2016)
Genomic imprinting is an epigenetic mechanism causing monoallelic expression in a parent-of-origin-specific manner. Disruption of imprinted genes causes various neurological and psychiatric disorders. However, the role of imprinted genes in the brain
Externí odkaz:
https://doaj.org/article/f4a4fca13fe34b578cd9eff112f760af
Autor:
Yi-Sian Lin, Han-Ying Wang, De-Fong Huang, Pei-Fen Hsieh, Meng-Ying Lin, Chih-Hsuan Chou, I-Ju Wu, Guo-Jen Huang, Susan Shur-Fen Gau, Hsien-Sung Huang
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164164 (2016)
Dysfunction of RBFOX3 has been identified in neurodevelopmental disorders such as autism spectrum disorder, cognitive impairments and epilepsy and a causal relationship with these diseases has been previously demonstrated with Rbfox3 homozygous knock
Externí odkaz:
https://doaj.org/article/60587d07730446e385dd1b9eaeab9202
Autor:
Hsien-Sung Huang, Bong-June Yoon, Sherian Brooks, Robert Bakal, Janet Berrios, Rylan S Larsen, Michael L Wallace, Ji Eun Han, Eui Hwan Chung, Mark J Zylka, Benjamin D Philpot
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98383 (2014)
Genomic imprinting describes an epigenetic process through which genes can be expressed in a parent-of-origin-specific manner. The monoallelic expression of imprinted genes renders them particularly susceptible to disease causing mutations. A large p
Externí odkaz:
https://doaj.org/article/a7b5ea7f69264a6eb7f4b64a19dd775c
Autor:
Hsien-Sung Huang, Schahram Akbarian
Publikováno v:
PLoS ONE, Vol 2, Iss 8, p e809 (2007)
Dysfunction of prefrontal cortex in schizophrenia includes changes in GABAergic mRNAs, including decreased expression of GAD1, encoding the 67 kDa glutamate decarboxylase (GAD67) GABA synthesis enzyme. The underlying molecular mechanisms remain uncle
Externí odkaz:
https://doaj.org/article/dfdeef4ac18b4b578a0b0de544c72abb
Autor:
Hsien-Sung Huang, 黃憲松
88
Bovine pancreatic DNase I is an endonuclease and its molecular weight is 31 kDa. It needs divalent metal ions for its activity, and neutral or mild alkaline pH is an optimal catalytic environment. The Paneth cell of the human small intestinal
Bovine pancreatic DNase I is an endonuclease and its molecular weight is 31 kDa. It needs divalent metal ions for its activity, and neutral or mild alkaline pH is an optimal catalytic environment. The Paneth cell of the human small intestinal
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/20788313529135323002
