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IFNgamma-Induced IFIT5 Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer via miRNA Processing

Autor: Lo UG, Pong RC, Yang D, Gandee L, Hernandez E, Dang A, Lin CJ, Santoyo J, Ma S, Sonavane R, Huang J, Tseng SF, Moro L, Arbini AA, Kapur P, Raj GV, He D, Lai CH, Lin H, Hsieh JT.

Publikováno v: Cancer research (Chic. Ill., Online) (2019).
info:cnr-pdr/source/autori:Lo UG, Pong RC, Yang D, Gandee L, Hernandez E, Dang A, Lin CJ, Santoyo J, Ma S, Sonavane R, Huang J, Tseng SF, Moro L, Arbini AA, Kapur P, Raj GV, He D, Lai CH, Lin H, Hsieh JT./titolo:IFNgamma-Induced IFIT5 Promotes Epithelial-to-Mesenchymal Transition in Prostate Cancer via miRNA Processing/doi:/rivista:Cancer research (Chic. Ill., Online)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume

IFNgamma, a potent cytokine known to modulate tumor immunity and tumoricidal effects, is highly elevated in patients with prostate cancer after radiation. In this study, we demonstrate that IFN? can induce epithelial-to-mesenchymal transition (EMT) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::33b95f0e91c067ed3a9c49ed6adf7c1d
http://www.cnr.it/prodotto/i/433436

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The mitochondrial genome encodes abundant small noncoding RNAs

Autor: Ro S, Ma HY, Park C, Ortogero N, Song R, Hennig GW, Zheng H, Lin YM, Moro L, Hsieh JT, Yan W

Publikováno v: Cell Research 23 (2013): 759–774.
info:cnr-pdr/source/autori:Ro S, Ma HY, Park C, Ortogero N, Song R, Hennig GW, Zheng H, Lin YM, Moro L, Hsieh JT, Yan W/titolo:The mitochondrial genome encodes abundant small noncoding RNAs./doi:/rivista:Cell Research/anno:2013/pagina_da:759/pagina_a:774/intervallo_pagine:759–774/volume:23

Small noncoding RNAs identified thus far are all encoded by the nuclear genome. Here, we report that the murine and human mitochondrial genomes encode thousands of small noncoding RNAs, which are predominantly derived from the sense transcripts of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::2d75cf7d578b269528df1e0e21afc432
https://publications.cnr.it/doc/258658

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Skp2 overexpression is associated with loss of BRCA2 protein in human prostate cancer

Autor: Arbini AA, Greco M, Yao JL, Bourne P, Marra E, Hsieh JT, di Sant'agnese PA, Moro L.

Publikováno v: The American journal of pathology
178 (2011): 2367–2376.
info:cnr-pdr/source/autori:Arbini AA, Greco M, Yao JL, Bourne P, Marra E, Hsieh JT, di Sant'agnese PA, Moro L./titolo:Skp2 overexpression is associated with loss of BRCA2 protein in human prostate cancer/doi:/rivista:The American journal of pathology (Print)/anno:2011/pagina_da:2367/pagina_a:2376/intervallo_pagine:2367–2376/volume:178

BRCA2 (breast cancer 2, early onset) is a tumor suppressor gene that confers increased susceptibility for prostate cancer (PCa). Previous in vitro experiments demonstrated that Skp2, an E3 ubiquitin ligase aberrantly overexpressed in PCa, is involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::c9ba5a326061078079284e309e456da7
https://publications.cnr.it/doc/12926

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Aromatase deficiency inhibits the permeability transition in mouse liver mitochondria

Autor: Moro L, Arbini AA, Hsieh JT, Ford J, Simpson ER, Hajibeigi A, Oz OK

Publikováno v: Endocrinology (Philadelphia) 151 (2010): 1643–1652.
info:cnr-pdr/source/autori:Moro L, Arbini AA, Hsieh JT, Ford J, Simpson ER, Hajibeigi A, Oz OK/titolo:Aromatase deficiency inhibits the permeability transition in mouse liver mitochondria/doi:/rivista:Endocrinology (Philadelphia)/anno:2010/pagina_da:1643/pagina_a:1652/intervallo_pagine:1643–1652/volume:151

Lack of estrogens affects male physiology in a number of ways, including severe changes in liver metabolism that result in lipid accumulation and massive hepatic steatosis. Here we investigated whether estrogen deficiency may alter the functionality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::f6aaaeb32223e411910de7fbac691e2f
https://publications.cnr.it/doc/12900

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