Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Hsiao-Ping H. Moore"'
Autor:
Gopal Iyer, Shimon Weiss, Hsiao-Ping H. Moore, Fabien Pinaud, Emmanuel Margeat, Xavier Michalet
Publikováno v:
Traffic. 10:691-712
Recent experimental developments have led to a revision of the classical fluid mosaic model proposed by Singer and Nicholson more than 35 years ago. In particular, it is now well established that lipids and proteins diffuse heterogeneously in cell pl
Publikováno v:
Journal of Biological Chemistry. 284:3049-3057
Cellular lipid metabolism is regulated in part by protein-protein interactions near the surface of intracellular lipid droplets. This work investigated functional interactions between Abhd5, a protein activator of the lipase Atgl, and Mldp, a lipid d
Autor:
Robert B. Silver, Hsiao Ping H Moore, Emilio P. Mottillo, James G. Granneman, David A. Bernlohr
Publikováno v:
Journal of Biological Chemistry. 280:43109-43120
Adipocytes serve as the principal energy reservoir of the body; however, the subcellular organization of the machinery regulating lipid trafficking and metabolism is poorly understood. Mobilization of stored triglyceride is thought be controlled by i
Publikováno v:
Journal of the American Chemical Society. 126:6115-6123
Synthetic phytochelatin-related peptides are used as an organic coat on the surface of colloidal CdSe/ZnS semiconductor nanocrystals synthesized from hydrophobic coordinating trioctyl phosphine oxide (TOPO) solvents. The peptides are designed to bind
Intracellular lipolysis is an important cellular process in key metabolic tissues, and while much is known about the enzymatic basis of lipolysis, our understanding of how these processes are organized and regulated within cells is incomplete. Lipoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf26550fc743b7306e154289cb3119c6
https://doi.org/10.1016/b978-0-12-800280-3.00015-3
https://doi.org/10.1016/b978-0-12-800280-3.00015-3
Publikováno v:
American Journal of Physiology-Cell Physiology. 281:C908-C921
Work addressing whether cystic fibrosis transmembrane conductance regulator (CFTR) plays a role in regulating organelle pH has remained inconclusive. We engineered a pH-sensitive excitation ratiometric green fluorescent protein (pHERP) and targeted i
Autor:
Michael Grabe, Terry E. Machen, Stephen R. Adams, Minnie M. Wu, Hsiao-Ping H. Moore, Roger Y. Tsien
Publikováno v:
Journal of Biological Chemistry. 276:33027-33035
A precise pH gradient between organelles of the regulated secretory pathway is required for sorting and processing of prohormones. We studied pH regulation in live endocrine cells by targeting biotin-based pH indicators to cellular organelles express
Autor:
William S. Trimble, Hsiao-Ping H. Moore, Alan D. Schreiber, Xiao-Rong Peng, Sergio Grinstein, Lydia Bajno
Publikováno v:
Journal of Cell Biology. 149:697-706
Phagocytosis involves the receptor-mediated extension of plasmalemmal protrusions, called pseudopods, which fuse at their tip to engulf a particle. Actin polymerizes under the nascent phagosome and may propel the protrusion of pseudopods. Alternative
Autor:
Stephen R. Adams, Hsiao-Ping H. Moore, Roger Y. Tsien, Markku S. Kulomaa, Juan Llopis, Minnie M. Wu, Terry E. Machen, J. Michael McCaffery
Publikováno v:
Chemistry & Biology. 7(3):197-209
Background: Mammalian organelles of the secretory pathway are of differing pH. The pH values form a decreasing gradient: the endoplasmic reticulum (ER) is nearly neutral, the Golgi is mildly acidic and the secretory granules are more acidic still (
Publikováno v:
American Journal of Physiology-Cell Physiology. 277:C361-C372
Stimulation of the gastric parietal cell results in a massive redistribution of H+-K+-ATPase from cytoplasmic tubulovesicles to the apical plasma membrane. Previous studies have implicated the small GTPase rab11 in this process. Using matrix-assisted