Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hsiao D. Lieu"'
Autor:
Arun J. Sanyal, Lei Ling, Ulrich Beuers, Alex M. DePaoli, Hsiao D. Lieu, Stephen A. Harrison, Gideon M. Hirschfield
Publikováno v:
JHEP Reports, Vol 3, Iss 3, Pp 100255- (2021)
Summary: Background & Aims: Higher serum bile acid levels are associated with an increased risk of cirrhosis and liver-related morbidity and mortality. Herein, we report secondary analyses of aldafermin, an engineered analogue of the gut hormone fibr
Externí odkaz:
https://doaj.org/article/ccc082e5733f41d1b166976e660a219c
Autor:
Duy M. Dinh, Alex M. DePaoli, Rohit Loomba, Stephen A. Harrison, Lei Ling, Arun J. Sanyal, Hsiao D. Lieu
Publikováno v:
Hepatology (Baltimore, Md.)
Background and aims The composition of the human gut microbiota is linked to health and disease, and knowledge of the impact of therapeutics on the microbiota is essential to decipher their biological roles and to gain new mechanistic insights. Here
Autor:
Stephen A Harrison, Manal F Abdelmalek, Guy Neff, Nadege Gunn, Cynthia D Guy, Naim Alkhouri, Mustafa R Bashir, Bradley Freilich, Anita Kohli, Arun Khazanchi, Muhammad Y Sheikh, Mark Leibowitz, Mary E Rinella, Mohammad S Siddiqui, Mark Kipnes, Sam E Moussa, Ziad H Younes, Meena Bansal, Seth J Baum, Brian Borg, Peter J Ruane, Paul J Thuluvath, Mildred Gottwald, Mujib Khan, Charles Chen, Liza Melchor-Khan, William Chang, Alex M DePaoli, Lei Ling, Hsiao D Lieu
Publikováno v:
The lancet. Gastroenterologyhepatology. 7(7)
Non-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis, inflammation, and injury, and is associated with an increased risk of liver transplantation and death. NASH affects more than 16 million people in the USA, and there is no ap
Autor:
Hsiao D. Lieu, Gideon M. Hirschfield, Arun J. Sanyal, Stephen A. Harrison, Lei Ling, Ulrich Beuers, Alex M. DePaoli
Publikováno v:
JHEP Reports
JHEP Reports, Vol 3, Iss 3, Pp 100255-(2021)
JHEP Reports, 3(3):100255. Elsevier
JHEP Reports, Vol 3, Iss 3, Pp 100255-(2021)
JHEP Reports, 3(3):100255. Elsevier
Summary Background & Aims Higher serum bile acid levels are associated with an increased risk of cirrhosis and liver-related morbidity and mortality. Herein, we report secondary analyses of aldafermin, an engineered analogue of the gut hormone fibrob
Autor:
Kristin Nelson, Hsiao D. Lieu, Mildred Gottwald, James F. Trotter, Guy W. Neff, Nadege Gunn, Alex M. DePaoli, Sam E. Moussa, Ziad Younes, Andrew Yan, Mustafa R. Bashir, Angelo H. Paredes, Juan P. Frias, William C.G. Chang, Cynthia D. Guy, Stephen A. Harrison, Lei Ling, Anita Kohli
Publikováno v:
Gastroenterology. 160(1)
Background & Aims Aldafermin, an engineered analog of fibroblast growth factor 19, inhibits bile acid synthesis and regulates metabolic homeostasis. We report results from a 24-week, phase 2 study, with serial liver biopsies, of patients with nonalco
Autor:
Chad Moretz, Hsiao D. Lieu, Frank R. Ernst, Douglas E. Faries, Mark B. Effron, Zhenxiang Zhao, JP Bae, Craig Lipkin
To compare 30 and 90 day real-world acute myocardial infarction (AMI) and bleeding related rehospitalization rates in acute coronary syndrome (ACS) patients receiving percutaneous coronary intervention (PCI; ACS-PCI) treated with clopidogrel or prasu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6ec181f13de3df58fd62906313fba5
Autor:
Douglas E. Faries, Craig Lipkin, Chad Moretz, Zhenxiang Zhao, Hsiao D. Lieu, Mark B. Effron, Frank R. Ernst, JP Bae
Publikováno v:
American Journal of Health-System Pharmacy. 73:395-403
Purpose Results of a study of bleeding events and other inhospital outcomes with the use of clopidogrel versus prasugrel in patients with acute coronary syndrome (ACS) managed with percutaneous coronary intervention (PCI) are reported. Methods Demogr
Autor:
Won Chan Lee, Hsiao D. Lieu, Mark B. Effron, Jingsong Lu, Yajun Zhu, Mitch DeKoven, Swapna Karkare, Cynthia Larmore, Cliff Molife, George W. Vetrovec
Publikováno v:
Catheterization and Cardiovascular Interventions. 88:535-544
Objectives: The 30-day clinical outcomes with prasugrel or ticagrelor were comparedusing a US payer database in patients with acute coronary syndrome (ACS) undergoingpercutaneous coronary intervention (PCI).Background: Prasugrel and ticagrelor dem-on
Autor:
Hsiao D. Lieu, Gregory S. Thomas, Charles E. Phelps, John A. McPherson, Alexandra J. Lansky, Pamela S. Douglas, Joseph A. Ladapo, Susan E. Daniels, Michael Elashoff, Szilard Voros, Mary E. Winn, Andrea Johnson, Timothy M. Bateman, Steven A. Rosenberg
Publikováno v:
Circulation: Cardiovascular Genetics. 6:154-162
Background— Obstructive coronary artery disease diagnosis in symptomatic patients often involves noninvasive testing before invasive coronary angiography. A blood-based gene expression score (GES) was previously validated in nondiabetic patients re
Autor:
Eric J. Topol, Robert S. Schwartz, Alexandra J. Lansky, Bradley O. Brown, Stephen G. Ellis, Ron Waksman, Michael Elashoff, John A. McPherson, Hsiao D. Lieu, Steven A. Rosenberg, William E. Kraus, Szilard Voros
Publikováno v:
Journal of Cardiovascular Translational Research
The majority of first-time angiography patients are without obstructive coronary artery disease (CAD). A blood gene expression score (GES) for obstructive CAD likelihood was validated in the PREDICT study, but its relation to major adverse cardiovasc