Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Hsiao‐Sheng Liu"'
Autor:
Pei‐Wen Lin, Man‐Ling Chu, Yu‐Wen Liu, Yu‐Cing Chen, Yao‐Hsiang Shih, Sheng‐Hui Lan, Shang‐Ying Wu, I‐Ying Kuo, Hong‐Yi Chang, Hsiao‐Sheng Liu, Ying‐Ray Lee
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 642-649 (2024)
Abstract Autophagy can be classified as degradative and secretory based on distinct functions. The small GTPase proteins Rab8a and Rab37 are responsible for secretory autophagy‐mediated exocytosis of IL‐1β, insulin, and TIMP1 (tissue inhibitor o
Externí odkaz:
https://doaj.org/article/e258c7ae7ddd4ed3a3137a5a976dbe9c
Autor:
Hsiao‐Sheng Liu, Yin‐Ping Wang, Pei‐Wen Lin, Man‐Ling Chu, Sheng‐Hui Lan, Shan‐Ying Wu, Ying‐Ray Lee, Hong‐Yi Chang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 631-641 (2024)
Abstract Autophagy is a self‐recycling machinery to maintain cellular homeostasis by degrading harmful materials in the cell. Autophagy‐related gene 5 (Atg5) is required for autophagosome maturation. However, the role of Atg5 in tumorigenesis und
Externí odkaz:
https://doaj.org/article/f842293ee22c4ac499453b39c2812390
Autor:
Thi-Huong Nguyen, Huey-Jiun Ko, Po-Yu Tsai, Tai-Shan Cheng, Thu-Ha Tran, Ly Hien Doan, Michael Hsiao, Peter Mu-Hsin Chang, Hsiao-Sheng Liu, Yi-Ren Hong, Chi-Ying F. Huang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Colorectal cancer (CRC) is one of the primary contributors to cancer-related fatalities, with up to 80% of advanced CRC cases exhibiting mutations in the p53 gene. Unfortunately, the development of new compounds targeting mutant p53 is quite limited.
Externí odkaz:
https://doaj.org/article/175e1107fd754719a53e6fa4e741b36b
Autor:
Sin-Yu Chen, Yi-Ling Chen, Po-Chen Li, Tai-Shan Cheng, Yeh-Shiu Chu, Yi-Shan Shen, Hsin-Tung Chen, Wei-Ni Tsai, Chien-Ling Huang, Martin Sieber, Yuan-Chieh Yeh, Hsiao-Sheng Liu, Chi-Ling Chiang, Chih-Hung Chang, Andrew S. Lee, Yen-Han Tseng, Ly James Lee, Hsiu-Jung Liao, Hon-Kan Yip, Chi-Ying F. Huang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-18 (2024)
Abstract Background Acute lung injury (ALI) is a life-threatening respiratory condition characterized by severe inflammation and lung tissue damage, frequently causing rapid respiratory failure and long-term complications. The microRNA let-7a-5p is i
Externí odkaz:
https://doaj.org/article/9dec6478d6d34d14974d0294891227b6
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Colorectal cancer (CRC) is a highly prevalent cancer type with limited targeted therapies available and 5-year survival rate, particularly for late-stage patients. There have been numerous attempts to repurpose drugs to tackle thi
Externí odkaz:
https://doaj.org/article/82dd31a911264a7fbbfb2385751a9d13
Autor:
Man‐Ling Chu, Pei‐Wen Lin, Yu‐Wen Liu, Shan‐Ying Wu, Sheng‐Hui Lan, Chun‐Li Su, Hsiao‐Sheng Liu
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 5, Pp 489-500 (2023)
Abstract Formosanin C (FC) is a natural compound extracted from Paris formosana Hayata with anticancer activity. FC induces both autophagy and apoptosis in human lung cancer cells. FC‐induced depolarization of mitochondrial membrane potential (MMP)
Externí odkaz:
https://doaj.org/article/4d919fd7ccc7474c9776b02b6282a07f
Autor:
Shan-Ying Wu, Jia-Wen Chen, Hsi-Yu Liu, Yi-Ching Wang, Yeh-Shiu Chu, Chi-Ying Huang, Kai-Ying Lan, Hsiao-Sheng Liu, Sheng-Hui Lan
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1), an inflammatory cytokine, under serum-depleted conditions which leads to suppression of lung cancer cell metastasis has been reported. Starvation is als
Externí odkaz:
https://doaj.org/article/7903b545231c4c54a14c56fea5a03f20
Autor:
Hong-Yi Chang, Chi-Hua Lee, Yi-Syuan Li, Jing-Tong Huang, Sheng-Hui Lan, Yi-Fang Wang, Wu-Wei Lai, Yi-Ching Wang, Yan-Ju Lin, Hsiao-Sheng Liu, Hung-Chi Cheng
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is widely prevalent in Taiwan, and high metastatic spread of ESCC leads to poor survival rate. Fibronectin (FN) assembly on the cell membrane may induce ESCC mobility. MicroRNAs (MiRNAs) a
Externí odkaz:
https://doaj.org/article/7d791233644e407588c6f294fa56885a
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 36, Iss 11, Pp 911-919 (2020)
Abstract We previously reported that dengue virus (DENV)‐induced autophagy plays a promoting role in viral replication and pathogenesis both in vitro and in vivo. Although it is known that DENV infection increases glycolysis, which promotes viral r
Externí odkaz:
https://doaj.org/article/8e62004f53da45b1aad2343d943728b4
Autor:
Yuan-Chieh Yeh, Ly Hien Doan, Zi-Yi Huang, Li-Wei Chu, Tzu-Hau Shi, Ying-Ray Lee, Cheng-Tao Wu, Chao-Hsiung Lin, Shu-Tuan Chiang, Hui-Kang Liu, Tsung-Hsien Chuang, Yueh-Hsin Ping, Hsiao-Sheng Liu, Chi-Ying F. Huang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
COVID-19 is threatening human health worldwide but no effective treatment currently exists for this disease. Current therapeutic strategies focus on the inhibition of viral replication or using anti-inflammatory/immunomodulatory compounds to improve
Externí odkaz:
https://doaj.org/article/4d184f88a03e480a94e0605248bc7332